Patents by Inventor William Zuercher

William Zuercher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE
    Publication number: 20240208910
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Application
    Filed: October 20, 2023
    Publication date: June 27, 2024
    Applicant: Dermavant Sciences GmbH
    Inventors: Channa K. JAYAWICKREME, Susan H. SMITH, Cunyu ZHANG, William ZUERCHER
  • Isoquinoline compounds and their use in treating AhR imbalance
    Patent number: 11827605
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: November 28, 2023
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Channa K. Jayawickreme, Susan H. Smith, Cunyu Zhang, William Zuercher
  • ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE
    Publication number: 20230124135
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Application
    Filed: October 28, 2022
    Publication date: April 20, 2023
    Applicant: Dermavant Sciences GmbH
    Inventors: Channa K. JAYAWICKREME, Susan H. SMITH, Cunyu ZHANG, William ZUERCHER
  • Isoquinoline compounds and their use in treating AhR imbalance
    Patent number: 11548853
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: January 10, 2023
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Channa K. Jayawickreme, Susan H. Smith, Cunyu Zhang, William Zuercher
  • ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE
    Publication number: 20220153703
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 19, 2022
    Inventors: Channa K. JAYAWICKREME, Susan H. SMITH, Cunyu ZHANG, William ZUERCHER
  • Isoquinoline compounds and their use in treating AhR imbalance
    Patent number: 11267788
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: March 8, 2022
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Channa K. Jayawickreme, Susan H. Smith, Cunyu Zhang, William Zuercher
  • ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE
    Publication number: 20220017468
    Abstract: The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
    Type: Application
    Filed: May 27, 2021
    Publication date: January 20, 2022
    Inventors: Channa K. JAYAWICKREME, Susan H. SMITH, Cunyu ZHANG, William ZUERCHER
  • Chemical Compounds
    Publication number: 20080221176
    Abstract: This invention relates to compounds that are modulators of the liver X receptors (LXRs), and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: August 23, 2006
    Publication date: September 11, 2008
    Inventors: John Loren Collins, Eugene Lee Stewart, William Zuercher, Esther Chao, Robert Wiethe, Justin Caravella
  • Chemical Compounds
    Publication number: 20070213348
    Abstract: The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
    Type: Application
    Filed: May 14, 2007
    Publication date: September 13, 2007
    Inventors: Jonathan Britton, Jing Fang, Dennis Heyer, Aaron Miller, Frank Navas, Terrence Smalley, William Zuercher, Subba Katamreddy
  • Substituted Quinoline Compounds For Use As Selective Estrogen Receptor Modulator
    Publication number: 20070203180
    Abstract: The present invention relates to novel compounds of formula (I) with a variety of therapeutic uses, more particularly novel substituted quinoline compounds particularly useful for selective estrogen receptor modulation.
    Type: Application
    Filed: February 22, 2005
    Publication date: August 30, 2007
    Inventors: William Hoekstra, Aaron Miller, William Zuercher, Harikrishna Patel
  • Cycloalkylidene compounds as modulators of estrogen receptor
    Publication number: 20070155839
    Abstract: The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
    Type: Application
    Filed: July 27, 2004
    Publication date: July 5, 2007
    Inventors: Jonathan Britton, Jing Fang, Dennis Heyer, Aaron Miller, Frank Navas, Terrence Smalley, William Zuercher, Subba Katamreddy