Patents by Inventor Williamson Z. Bradford

Williamson Z. Bradford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Administering Pirfenidone Therapy
    Publication number: 20160228423
    Abstract: The disclosure relates to improved methods of administering pirfenidone therapy when ciprofloxacin is administered concomitantly.
    Type: Application
    Filed: April 13, 2016
    Publication date: August 11, 2016
    Inventor: Williamson Z. Bradford
  • PIRFENIDONE THERAPY AND INDUCERS OF CYTOCHROME P450
    Publication number: 20150342941
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Application
    Filed: August 13, 2015
    Publication date: December 3, 2015
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • PIRFENIDONE AND ANTI-FIBROTIC THERAPY IN SELECTED PATIENTS
    Publication number: 20150164874
    Abstract: The present invention relates to methods of treating pulmonary fibrosis with pirfenidone and/or other agents.
    Type: Application
    Filed: May 25, 2012
    Publication date: June 18, 2015
    Applicant: INTERMUNE, INC.
    Inventor: Williamson Z. Bradford
  • PIRFENIDONE THERAPY AND INDUCERS OF CYTOCHROME P450
    Publication number: 20150111899
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Application
    Filed: December 23, 2014
    Publication date: April 23, 2015
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Methods of Administering Pirfenidone Therapy
    Publication number: 20140350060
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
    Type: Application
    Filed: August 8, 2014
    Publication date: November 27, 2014
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Methods of administering pirfenidone therapy
    Patent number: 8778947
    Abstract: The disclosure relates to improved methods of administering pirfenidone therapy when ciprofloxacin is administered concomitantly.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: July 15, 2014
    Assignee: Intermune, Inc.
    Inventor: Williamson Z. Bradford
  • Pirfenidone therapy and inducers of cytochrome P450
    Patent number: 8754109
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: June 17, 2014
    Assignee: Intermune, Inc.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Pirfenidone Treatment for Patients with Atypical Liver Function
    Publication number: 20140073673
    Abstract: Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.
    Type: Application
    Filed: November 12, 2013
    Publication date: March 13, 2014
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Swarcberg
  • METHODS OF ADMINISTERING PIRFENIDONE THERAPY
    Publication number: 20140066484
    Abstract: The disclosure relates to improved methods of administering pirfenidone therapy when ciprofloxacin is administered concomitantly.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 6, 2014
    Applicant: INTERMUNE, INC.
    Inventor: Williamson Z. Bradford
  • Method of providing pirfenidone therapy to a patient
    Patent number: 8420674
    Abstract: The invention relates to methods for decreasing adverse events associated with pirfenidone (5-methyl-1-phenyl-2-(1H)-pyridone) therapy. The invention discloses an optimized dose escalation scheme that results in the patient having increased tolerance to adverse events associated with the administration of pirfenidone. The invention also discloses a starter pack that may be used in conjunction with the dose escalation scheme.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: April 16, 2013
    Assignee: Intermune, Inc.
    Inventor: Williamson Z. Bradford
  • PIRFENIDONE THERAPY AND INDUCERS OF OF CYTOCHROME P450
    Publication number: 20130045997
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Application
    Filed: December 3, 2010
    Publication date: February 21, 2013
    Applicant: INTERMUNE, INC
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Method of Administering Pirfenidone Therapy
    Publication number: 20130030024
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
    Type: Application
    Filed: December 3, 2010
    Publication date: January 31, 2013
    Applicant: INTERMUNE ,INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Pirfenidone Therapy and Inducers of Cytochrome P450
    Publication number: 20120088801
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Application
    Filed: December 15, 2011
    Publication date: April 12, 2012
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • PIRFENIDONE TREATMENT FOR PATIENTS WITH ATYPICAL LIVER FUNCTION
    Publication number: 20120077850
    Abstract: Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.
    Type: Application
    Filed: December 6, 2011
    Publication date: March 29, 2012
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Methods of Administering Pirfenidone Therapy
    Publication number: 20120015985
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
    Type: Application
    Filed: September 26, 2011
    Publication date: January 19, 2012
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Methods of Administering Pirfenidone Therapy
    Publication number: 20110319453
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
    Type: Application
    Filed: September 2, 2011
    Publication date: December 29, 2011
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Pirfenidone Treatment for Patients with Atypical Liver Function
    Publication number: 20110263656
    Abstract: Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.
    Type: Application
    Filed: November 9, 2009
    Publication date: October 27, 2011
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • PIRFENIDONE THERAPY AND INDUCERS OF CYTOCHROME P450
    Publication number: 20110172277
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with pirfenidone and CYP inducers, such as smoking.
    Type: Application
    Filed: January 8, 2010
    Publication date: July 14, 2011
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • METHODS OF ADMINISTERING PIRFENIDONE THERAPY
    Publication number: 20110166186
    Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.
    Type: Application
    Filed: March 16, 2011
    Publication date: July 7, 2011
    Applicant: INTERMUNE, INC.
    Inventors: Williamson Z. Bradford, Javier Szwarcberg
  • Method of Providing Pirfenidone Therapy to a Patient
    Publication number: 20100324097
    Abstract: The invention relates to methods for decreasing adverse events associated with pirfenidone (5-methyl-1-phenyl-2-(1H)-pyridone) therapy. The invention discloses an optimized dose escalation scheme that results in the patient having increased tolerance to adverse events associated with the administration of pirfenidone. The invention also discloses a starter pack that may be used in conjunction with the dose escalation scheme.
    Type: Application
    Filed: July 7, 2010
    Publication date: December 23, 2010
    Applicant: INTERMUNE, INC.
    Inventor: Williamson Z. Bradford