Patents by Inventor Willscott Naugler

Willscott Naugler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NORMALIZATION OF THE ENTEROHEPATIC CIRCULATION IN ANIMALS WITH A CHIMERIC HUMANIZED LIVER
    Publication number: 20170105395
    Abstract: Methods of normalizing bile acid production in a mouse engrafted with human hepatocytes by the administration of human FGF19 are disclosed. Also disclosed is a transgenic host animal, such as a mouse, that expresses human FGF19 that has normalized bile acid production when engrafted with human hepatocytes.
    Type: Application
    Filed: December 29, 2016
    Publication date: April 20, 2017
    Applicant: OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Markus Grompe, Willscott Naugler
  • Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
    Patent number: 9566315
    Abstract: Methods of normalizing bile acid production in a mouse engrafted with human hepatocytes by the administration of human FGF19 are disclosed. Also disclosed is a transgenic host animal, such as a mouse, that expresses human FGF19 that has normalized bile acid production when engrafted with human hepatocytes.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: February 14, 2017
    Assignee: OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Markus Grompe, Willscott Naugler
  • NORMALIZATION OF THE ENTEROHEPATIC CIRCULATION IN ANIMALS WITH A CHIMERIC HUMANIZED LIVER
    Publication number: 20150128299
    Abstract: Methods of normalizing bile acid production in a mouse engrafted with human hepatocytes by the administration of human FGF19 are disclosed. Also disclosed is a transgenic host animal, such as a mouse, that expresses human FGF19 that has normalized bile acid production when engrafted with human hepatocytes.
    Type: Application
    Filed: October 30, 2014
    Publication date: May 7, 2015
    Applicant: OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Markus Grompe, Willscott Naugler