Abstract: An atraumatic detection/stimulation lead is disclosed. The lead includes at least one microcable having a core cable comprising a plurality of elementary metal strands. One of the microcables has provided at its distal end an atraumatic protection device. The atraumatic protection device includes a protective coating on the distal ends of the elementary strands of the microcable, and the protective coating is covered by a protective cap of deformable material. The protective cap may be a conical distal end adapted to deform and axially flatten out. The microcable may have an overall diameter less than or equal to 1.5 French (0.50 mm).

Abstract: A microlead has a distal active portion formed by a microcable including an electrically conductive core coated with an insulation layer, with a plurality of exposed areas forming the stimulation electrodes. The microcable has a three-dimensional preshape inscribed in a cylindrical envelope volume so as to match the target vessel wall. The microcable includes a plurality of exposed areas regularly distributed over the circumference of the cylindrical envelope volume considered in axial projection, the exposed zones extending only over an angular sector of the microcable considered in cross section, said angular sector facing the outside of the envelope volume of the preshape.

Abstract: The invention relates to an implantable capsule, particularly an autonomous capsule of cardiac stimulation, including a tubular body provided at the distal end of an anchoring element with a helical screw adapted to penetrate tissue a wall of an organ of a patient, the body housing a set of functional elements of the capsule. It includes, in an annular area surrounding the base of the screw recessed arrangements defining a set of flush tips oriented in a circumferential direction opposite to that of the screwing, to avoid the unscrewing of the capsule.

Abstract: This accessory comprises a remotely steerable catheter (40) extended by a tip (50) comprising a base (52) to which the catheter (40) connects to and a cylindrical portion (54) defining a volume (56) suitable for housing the capsule (10). A sub-catheter (30) and the capsule are telescopically extendable with respect to the catheter between i) a retracted position and a deployed position wherein the capsule is removed from the connector and is carried by the distal end of the sub-catheter, and the distal end of sub-catheter and the proximal region (18) of the capsule being provided with disconnectable means of attachment (20, 36). The tip presents, between its base (52) and its cylindrical portion (54), a flexible portion (58) providing, between the base and the cylindrical portion, an elastic deformability in bending and compression.

Abstract: The device comprises a sealed body housing electronic circuits, and extending from said body, a microlead comprising microcables connected to remote electrodes. The device has no connector between the microlead and the electronic circuits. Each microcable is permanently connected to its pole by connection means. The connection means comprises an insulating base hermetically crossed by feedthrough pins, a support for the base, conductive connection parts each comprising a first passage for a microcable and a second passage for a feedthrough pin, an insulating guiding and holding part mounted on the support and locked thereon. The guiding and holding part having cavities for the connection parts, each cavity opening in its bottom on a passage wherein a pin projects. The device also includes a transition and protection element encapsulating the guiding and holding part, the connection parts and the adjoining regions of the microcables.

Abstract: The invention relates to an implantable capsule, particularly an autonomous capsule of cardiac stimulation, comprising a tubular body provided at the distal end of an anchoring element with a helical screw adapted to penetrate tissue a wall of an organ of a patient, the body housing a set of functional elements of the capsule. It comprises an annular support integral with the body and coaxial therewith, said support surrounding the base of the anchoring element and comprising a series of openings radially extending. The base of the anchoring element comprises a series of rods or tubes projecting in a generally radial direction, and engaged in said openings to thereby secure the anchoring element to the support.

Abstract: An atraumatic detection/stimulation lead is disclosed. The lead includes at least one microcable having a core cable comprising a plurality of elementary metal strands. One of the microcables has provided at its distal end an atraumatic protection device. The atraumatic protection device includes a protective coating on the distal ends of the elementary strands of the microcable, and the protective coating is covered by a protective cap of deformable material. The protective cap may be a conical distal end adapted to deform and axially flatten out. The microcable may have an overall diameter less than or equal to 1.5 French (0.50 mm).

Abstract: This implantable microcatheter includes a hollow tube with a central lumen extending throughout the length of the tube from a proximal region to a distal region. The bending stiffness of the proximal region is greater than the bending stiffness of the distal region, and the tube has a transition region having a decreasing stiffness gradient from the proximal region to the distal region. The tube wall is free of shielding or armor at least in the distal region, and the catheter is made of biocompatible material(s) suitable for a permanent implantation in venous, arterial or lymphatic networks.

Abstract: An atraumatic detection/stimulation lead is disclosed. The lead includes at least one microcable having a core cable comprising a plurality of elementary metal strands. One of the microcables has provided at its distal end an atraumatic protection device. The atraumatic protection device includes a protective coating on the distal ends of the elementary strands of the microcable, and the protective coating is covered by a protective cap of deformable material. The protective cap may be a conical distal end adapted to deform and axially flatten out. The microcable may have an overall diameter less than or equal to 1.5 French (0.50 mm).

Abstract: A microlead includes exposed areas forming stimulation electrodes. The microlead further includes a stimulation zone (ZS) defined by a first preshape of the microcable at the distal end thereof, in a region including the electrodes (30). The microlead further includes a retention zone (ZR) including a retainer shape adapted to abut the wall of the target vessel. The microlead further includes a stretching zone (ZEL) proximal to the retention zone. The stretching zone may be defined by a shape adapted to make the region elastically deformable in the longitudinal direction under the effect of an axial traction/compression stress. The axial traction/compression stiffness in the elongation zone is lower than that in the retention and stimulation areas.

Abstract: A hybrid system forming an active implantable medical device includes a subcutaneous autonomous capsule and at least one intracorporeal autonomous leadless capsule. The subcutaneous capsule is a hybrid capsule having a seal body of dimensions comparable to those of a leadless capsule, but extended by a detection/stimulation microlead, without any intermediate connector. The leadless capsule includes a seal body, anchoring means in a wall of an organ and a detection/stimulation electrode. The hybrid capsule and the leadless capsules each include transmitter/receiver means for intracorporeal mutual wireless communication so as to constitute a network wherein the hybrid capsule is the master and leadless capsules are the slaves. The hybrid capsule further includes means for centralizing data transmitted by the leadless capsules and for exchanging data with remote external equipment.

Abstract: The invention relates to an implantable capsule, particularly an autonomous capsule of cardiac stimulation, including a tubular body provided at the distal end of an anchoring element with a helical screw adapted to penetrate tissue a wall of an organ of a patient, the body housing a set of functional elements of the capsule. It includes, in an annular area surrounding the base of the screw recessed arrangements defining a set of flush tips oriented in a circumferential direction opposite to that of the screwing, to avoid the unscrewing of the capsule.

Abstract: A method for constructing a plug for an electrical connection to a multipolar lead for an active implantable medical device includes providing a plug body having an insulating monobloc central core, the monobloc central core having a generally cylindrical shape, a cylindrical side surface, and a housing, providing a connection wire and a conductive pod, attaching the connection wire to the conductive pod, placing the conductive pod into the housing with connection wire extending therefrom, placing a conductive cylindrical ring on the cylindrical side surface, wherein the cylindrical side surface centers the conductive cylindrical ring coaxially about the monobloc central core, attaching the conductive pod to the cylindrical ring to create an electrical contact zone on a cylindrical outer surface of the plug body.

Abstract: The invention relates to an implantable capsule, particularly an autonomous capsule of cardiac stimulation, comprising a tubular body provided at the distal end of an anchoring element with a helical screw adapted to penetrate tissue a wall of an organ of a patient, the body housing a set of functional elements of the capsule. It comprises an annular support integral with the body and coaxial therewith, said support surrounding the base of the anchoring element and comprising a series of openings radially extending. The base of the anchoring element comprises a series of rods or tubes projecting in a generally radial direction, and engaged in said openings to thereby secure the anchoring element to the support.

Abstract: An autonomous capsule includes a tubular body provided at its distal end with an anchoring screw, and in its proximal region of a capture groove. An explantation accessory includes a reinforced catheter combined with a flexible wire which can slide in the catheter and has a deformable loop which can be clamped by gradual introduction of its ends in the catheter under the effect of a traction exerted on the wire. During tightening, the capture groove receives the wire loop, allowing, after complete tightening, to secure in tension and rotation an assembly formed by the catheter, the capsule, and the wire. The reinforced catheter is then used to transmit a tensile force and an axial torque from its proximal end to its distal end, allowing safe unscrewing of the capsule and its extraction through the patient venous network.

Abstract: A microlead has a distal active portion formed by a microcable including an electrically conductive core coated with an insulation layer, with a plurality of exposed areas forming the stimulation electrodes. The microcable has a three-dimensional preshape inscribed in a cylindrical envelope volume so as to match the target vessel wall. The microcable includes a plurality of exposed areas regularly distributed over the circumference of the cylindrical envelope volume considered in axial projection, the exposed zones extending only over an angular sector of the microcable considered in cross section, said angular sector facing the outside of the envelope volume of the preshape.

Abstract: An intracorporeal autonomous active medical device having a capsule body and a base. The capsule body includes a body portion and a lid portion, and the capsule body contains therein electronic circuitry containing the active elements of the autonomous medical device, and a power supply. The capsule body also includes a fastening system on an exterior surface of the capsule body that is configured to correspond with a fastening mechanism on the base configured to be anchored to a tissue wall. The fastening mechanism provides selective engagement between the capsule body and the base.

Abstract: This system includes a conductor microcable and an insulating microcatheter, including a hollow tube housing the microcable with the possibility of relative axial translation therebetween. The microcatheter is suitable for permanent implantation. The microcatheter, in its distal portion, includes at least one lateral window formed by a through orifice formed on the wall of the hollow tube. The window forms a stimulation site defined on the wall of the target vein facing the window of the microcatheter, and provides for a region of the microcable surface located at the window to form a stimulation electrode. In its distal portion, the microcable is not isolated at least in the region of the window of the microcatheter. The microcatheter is telescopically moveable on the microcable, so as to modify the position of the stimulation site of the target vein.

Abstract: A microlead includes exposed areas forming stimulation electrodes. The microlead further includes a stimulation zone (ZS) defined by a first preshape of the microcable at the distal end thereof, in a region including the electrodes (30). The microlead further includes a retention zone (ZR) including a retainer shape adapted to abut the wall of the target vessel. The microlead further includes a stretching zone (ZEL) proximal to the retention zone. The stretching zone may be defined by a shape adapted to make the region elastically deformable in the longitudinal direction under the effect of an axial traction/compression stress. The axial traction/compression stiffness in the elongation zone is lower than that in the retention and stimulation areas.

Abstract: An atraumatic detection/stimulation lead is disclosed. The lead includes at least one microcable having a core cable comprising a plurality of elementary metal strands. One of the microcables has provided at its distal end an atraumatic protection device. The atraumatic protection device includes a protective coating on the distal ends of the elementary strands of the microcable, and the protective coating is covered by a protective cap of deformable material. The protective cap may be a conical distal end adapted to deform and axially flatten out. The microcable may have an overall diameter less than or equal to 1.5 French (0.50 mm).