Patents by Inventor Wilm Buhr

Wilm Buhr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Sulfonaminoquinoline Hepcidin Antagonists
    Publication number: 20140364424
    Abstract: The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.
    Type: Application
    Filed: June 20, 2014
    Publication date: December 11, 2014
    Inventors: Wilm Buhr, Susanna Burckhardt, Franz Dürrenberger, Felix Funk, Peter O. Geisser, Vincent A. Corden, Stephen M. Courtney, Graham Dawson, Tara Davenport, Mark Slack, Mark P. Ridgill, Christopher J. Yarnold, Susan Boyce, Albertus A. Ellenbroek
  • Fe(III) 2,4-Dioxo-1-Carbonyl Complexes For Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anaemias
    Publication number: 20140248342
    Abstract: The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use in the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.
    Type: Application
    Filed: May 30, 2012
    Publication date: September 4, 2014
    Applicant: Vifor (International) AG
    Inventors: Thomas Bark, Wilm Buhr, Susanna Burckhardt, Michael Burgert, Camillo Canclini, Franz Dürrenberger, Felix Funk, Peter Geisser, Aris Kalogerakis, Simona Mayer, Erik Philipp, Stefan Reim, Diana Sieber, Jörg Schmitt, Katrin Schwarz, Jürgen Klotz
  • FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIAS
    Publication number: 20140162994
    Abstract: The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.
    Type: Application
    Filed: March 28, 2012
    Publication date: June 12, 2014
    Applicant: Vifor (International) AG
    Inventors: Thomas Bark, Wilm Buhr, Susanna Burckhardt, Michael Burgert, Camillo Canclini, Franz Dürrenberger, Felix Funk, Peter Otto Geisser, Aris Kalogerakis, Simona Mayer, Erik Philipp, Stefan Reim, Diana Sieber, Jörg Schmitt, Katrin Schwarz
  • Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias
    Publication number: 20130109662
    Abstract: The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.
    Type: Application
    Filed: March 22, 2011
    Publication date: May 2, 2013
    Applicant: Vifor (International) AG
    Inventors: Thomas Bark, Wilm Buhr, Susanna Burckhardt, Michael Burgert, Camillo Canclini, Franz Dürrenberger, Felix Funk, Peter Geisser, Aris Kalogerakis, Simona Mayer, Erik Philipp, Stefan Reim, Diana Sieber, Jörg Schmitt, Katrin Schwarz
  • Novel Ethanediamone Hepcidine Antagonists
    Publication number: 20120214798
    Abstract: The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
    Type: Application
    Filed: September 6, 2010
    Publication date: August 23, 2012
    Applicant: VIFOR (INTERNATIONAL) AG
    Inventors: Franz Dürrenberger, Susanna Burckhardt, Wilm Buhr, Peter O. Geisser, Felix Funk, Vincent A. Corden, Stephen M. Courtney, Tara Davenport, Stefan Jaeger, Mark P. Ridgill, Mark Slack, Christopher J. Yarnold, Wei Tsung Yau
  • Novel Sulfonaminoquinoline Hepcidin Antagonists
    Publication number: 20120214803
    Abstract: The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.
    Type: Application
    Filed: February 2, 2012
    Publication date: August 23, 2012
    Applicant: VIFOR (INTERNATIONAL) AG
    Inventors: Wilm Buhr, Susanna Burckhardt, Franz Dürrenberger, Felix Funk, Peter O. Geisser, Vincent A. Corden, Stephen M. Courtney, Graham Dawson, Tara Davenport, Mark Slack, Mark P. Ridgill, Chrostopher J. Yarnold, Susan Boyce, Albertus A. Ellenbroek
  • Novel Pyrimidine- And Triazine-Hepcidine Antagonists
    Publication number: 20120202806
    Abstract: The present invention relates to new hepcidin antagonists, pharmaceutical compositions containing them and the use thereof as a drug, in particular for the treatment of iron metabolism disorders such as, in particular, iron deficiency diseases and anaemia, in particular anaemia associated with chronic inflammatory disease (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
    Type: Application
    Filed: August 31, 2010
    Publication date: August 9, 2012
    Applicant: VIFOR (INTERNATIONAL) AG
    Inventors: Franz Dürrenberger, Susanna Burckhardt, Peter O. Geisser, Wilm Buhr, Felix Funk, Julia M. Bainbridge, Vincent A. Corden, Stephen M. Courtney, Tara Davenport, Stefan Jaeger, Mark P. Ridgill, Mark Slack, Christopher J. Yarnold, Wei Tsung Yau
  • Novel Quinoline-Hepcidine Antagonists
    Publication number: 20120196853
    Abstract: The present invention relates to novel hepcidin antagonists of the general formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
    Type: Application
    Filed: August 19, 2010
    Publication date: August 2, 2012
    Applicant: VIFOR (INTERNATIONAL) AG
    Inventors: Franz Dürrenberger, Susanna Burckhardt, Peter O. Geisser, Wilm Buhr, Felix Funk, Vincent A. Corden, Tara Davenport, Stefan Jaeger, Mark Slack, Christopher J. Yarnold, Wei Tsung Yau, Stephen M. Courtney
  • Spiro-benzimidazoles as inhibitors of gastric acid secretion
    Publication number: 20090093473
    Abstract: The invention provides compounds of the formula (I) In which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: June 13, 2006
    Publication date: April 9, 2009
    Inventors: Peter Jan Zimmermann, Jorg Senn-Bilfinger, Christof Brehm, Wilm Buhr, Maria Vittoria Chiesa, Andreas Palmer, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
    Publication number: 20080280855
    Abstract: The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: June 20, 2006
    Publication date: November 13, 2008
    Applicant: NYCOMED GmbH
    Inventors: Maria Vittoria Chiesa, Andreas Palmer, Wilm Buhr, Peter Jan Zimmermann, Christof Brehm, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer, Antonio Zanotti-Gerosa
  • Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion
    Publication number: 20080119510
    Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: December 6, 2005
    Publication date: May 22, 2008
    Applicant: Altana Pharma AG
    Inventors: Christof Brehm, Wilm Buhr, M. Vittoria Chiesa, Andreas Palmer, Peter Jan Zimmermann, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Cyclic benzimidazoles
    Publication number: 20080113963
    Abstract: The invention is directed to processes for preparing cyclic benzimidazoles, which compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: November 1, 2007
    Publication date: May 15, 2008
    Applicant: ALTANA PHARMA AG
    Inventors: M. Chiesa, Peter Zimmermann, Wilm Buhr
  • Condensed Tricyclic Benzimidazoles For the Treatment of Gastrointestinal Disorders
    Publication number: 20080113962
    Abstract: The invention relates to condensed tricyclic benzimidazoles of formula (I) in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Application
    Filed: September 30, 2005
    Publication date: May 15, 2008
    Applicant: Aitana Pharma AG
    Inventors: Peter Jan Zimmermann, Wilm Buhr, Christof Brehm, Andreas Palmer, M. Vittoria Chiesa, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
  • Difluoro-Substituted Imidazopyridines
    Publication number: 20080114020
    Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 15, 2008
    Applicant: Altana Pharma AG
    Inventors: Wilm Buhr, Peter Jan Zimmermann, Christof Brehm, Adreas Palmer, M.Vittoria Chiesa, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer, Georg Rast, Udo Doelling
  • 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
    Publication number: 20080033006
    Abstract: The invention provides compounds of the formula 1, in which the substituents and symbols are defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: January 25, 2005
    Publication date: February 7, 2008
    Applicant: Altana Pharma AG
    Inventor: Wilm Buhr
  • 8-Substituted imidazopyridines
    Patent number: 7326718
    Abstract: The present invention relates to 8-substituted imidazopyridines of a certain formula (1) in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Grant
    Filed: November 15, 2003
    Date of Patent: February 5, 2008
    Assignee: Altana Pharma AG
    Inventors: Wilm Buhr, Jörg Senn-Bilfinger, Peter Jan Zimmermann
  • Tricyclic n-acyl compounds
    Patent number: 7314935
    Abstract: The invention relates to compounds of the formula (1) where the substituents and symbols are as defined in the description. The compounds are valuable intermediates for preparing active pharmaceutical ingredients.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: January 1, 2008
    Assignee: Altana Pharma AG
    Inventors: Wilm Buhr, Jörg Senn-Bilfinger, Peter Jan Zimmerman, Peter Zimmerman
  • Cyclic benzimidazoles
    Patent number: 7307084
    Abstract: The invention relates to cyclic benzimidazoles of formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: December 11, 2007
    Assignee: Altana Pharma AG
    Inventors: Wilm Buhr, M. Vittoria Chiesa, Peter Jan Zimmermann
  • Amino-Halogen-Imidazopyridines as Proton Pump Inhibitors
    Publication number: 20070244115
    Abstract: The invention relates to compounds of the formula (1) and to medicaments comprising these compounds.
    Type: Application
    Filed: June 14, 2005
    Publication date: October 18, 2007
    Applicant: Alana Pharma AG
    Inventor: Wilm Buhr
  • 6,7-Dihydroxy-8-Phenyl-3,6,7,8-Tetrahydro-Chromeno [7,8-d] Imidazole Derivatives and Their Use as Gastric Acid Secretion Inhibitors
    Publication number: 20070244173
    Abstract: The invention provides compounds of the formula 1, in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
    Type: Application
    Filed: October 18, 2006
    Publication date: October 18, 2007
    Applicant: Altana Pharma AG
    Inventor: Wilm Buhr