Patents by Inventor Wilmin Bartolini

Wilmin Bartolini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Abdominal Pain Associated with Diarrhea-Predominant Irritable Bowel Syndrome
    Publication number: 20230346878
    Abstract: The invention provides methods for treating a patient with a disorder, such as a GI disorder or symptoms associated with a GI or non-GI disorder, by administering a therapeutically effective amount of a delayed release pharmaceutical composition comprising linaclotide.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 2, 2023
    Inventor: Wilmin Bartolini
  • Treatment of Abdominal Pain Associated with Diarrhea-Predominant Irritable Bowel Syndrome
    Publication number: 20230173016
    Abstract: The invention provides methods for treating a patient with a disorder, such as a GI disorder or symptoms associated with a GI or non-GI disorder, by administering a therapeutically effective amount of a delayed release pharmaceutical composition comprising linaclotide.
    Type: Application
    Filed: November 27, 2022
    Publication date: June 8, 2023
    Inventor: Wilmin Bartolini
  • Treatment of Abdominal Pain Associated with Diarrhea-Predominant Irritable Bowel Syndrome
    Publication number: 20220241367
    Abstract: The invention provides methods for treating a patient with a disorder, such as a GI disorder or symptoms associated with a GI or non-GI disorder, by administering a therapeutically effective amount of a delayed release pharmaceutical composition comprising linaclotide.
    Type: Application
    Filed: June 9, 2020
    Publication date: August 4, 2022
    Inventor: Wilmin Bartolini
  • Method of Generating Anti-Linaclotide Antibodies and Uses Thereof
    Publication number: 20210261690
    Abstract: The invention provides a method for producing anti-linaclotide antibodies or antigen fragments thereof and uses thereof.
    Type: Application
    Filed: May 9, 2019
    Publication date: August 26, 2021
    Inventors: Wilmin Bartolini, Marco Kessler
  • Method of Generating Anti-Linaclotide Antibodies and Uses Thereof
    Publication number: 20200148791
    Abstract: The invention provides a method for producing anti-linaclotide antibodies or antigen fragments thereof and uses thereof.
    Type: Application
    Filed: May 9, 2019
    Publication date: May 14, 2020
    Inventors: Wilmin Bartolini, Marco Kessler
  • CRTH2 modulators
    Patent number: 8674115
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 18, 2014
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Ara Mermerian, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini
  • CRTH2 MODULATORS
    Publication number: 20110150834
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Inventors: Ara MERMERIAN, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini
  • Useful indole compounds
    Patent number: 7960544
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: June 14, 2011
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Wilmin Bartolini, Brian M. Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • USEFUL INDOLE COMPOUNDS
    Publication number: 20090264653
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Application
    Filed: December 18, 2006
    Publication date: October 22, 2009
    Inventors: Wilmin Bartolini, Brian M Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • Useful indole compounds
    Publication number: 20070203209
    Abstract: Indoles having various activities, including indoles that are CRTH2 are described. The compounds are useful for treating asthma, neuropathic pain, allegic rhinitis and other disorders.
    Type: Application
    Filed: August 18, 2006
    Publication date: August 30, 2007
    Inventors: Wilmin Bartolini, Brian Cali, Barbara Chen, Yueh-Tyng Chien, Mark Currie, G. Milne, James Pearson, John Talley, Jing Yang, Craig Zimmerman, Alex Monreal
  • Modulators of CRTH2, COX-2 and FAAH
    Publication number: 20050234030
    Abstract: Certain substituted indoles that are modulators of one or more or of CRTH2, COX-2 AND FAAH are described. The compounds are useful for treatment of pain and/or inflammation as well as other disorders.
    Type: Application
    Filed: January 3, 2005
    Publication date: October 20, 2005
    Inventors: Wilmin Bartolini, Brian Cali, Barbara Chen, Yueh-Tyng Chien, Mark Currie, G. Milne, James Pearson, John Talley, Jing Yang, Craig Zimmerman
  • Synthesis of COX-2 and FAAH inhibitors
    Publication number: 20050234244
    Abstract: Methods for preparing indoles that are useful COX-2 inhibitors and intermediates useful in such methods are described.
    Type: Application
    Filed: November 1, 2004
    Publication date: October 20, 2005
    Inventors: Wilmin Bartolini, Brian Cali, Barbara Chen, Yueh-Tyng Chien, Mark Currie, G. Milne, James Pearson, John Talley, Craig Zimmerman
  • COX-2 and FAAH inhibitors
    Publication number: 20050032747
    Abstract: The invention features compounds that inhibit COX-2 and/or FAAH. The COX-2 inhibitors are selective COX-2 inhibitors in that they are selective for COX-2 compared to COX-1. Certain of the FAAH inhibitors are selective for FAAH relative to COX-2. Certain of the COX-2 inhibitors, in addition for being selective for COX-2 relative to COX-1, are selective for COX-2 relative to FAAH.
    Type: Application
    Filed: July 1, 2004
    Publication date: February 10, 2005
    Inventors: Wilmin Bartolini, Brian Cali, Barbara Chen, Yueh-Tyng Chien, Mark Currie, G. Milne, James Pearson, John Talley, Craig Zimmerman