Abstract: A method for making a cold plate includes the steps of positioning a finstock structure in a cavity of a substrate; and applying a cover to the finstock structure and substrate, wherein the applying step comprises ultrasonically additive manufacturing the cover to the substrate and the finstock structure, whereby the cover joins with the substrate and the finstock structure. The resulting cold plate assembly includes a substrate having a cavity, a finstock structure within the cavity, and a cover closing the finstock structure within the cavity, the cover being integrally joined to the substrate and to the finstock structure.

Abstract: Methods and systems for treating osteochondral defects (OCDs) are disclosed. The methods include collecting surface data of a joint using image-free methods, generating a three-dimensional (3D) healthy bone model based on the surface data and a database of healthy bone anatomies, defining a boundary of the OCD on the joint, and generating a 3D implant model based on the 3D healthy bone model and the boundary. The method may also include manufacturing an implant based on the 3D implant model, generating an implantation plan, resecting the joint according to the implantation plan, and placing the implant into the resected cavity. The 3D implant model may include a first and second porous layer separated by a nonporous layer. A polymer material is overmolded onto the second porous layer and treated to exhibit properties that mimic cartilage, while the first porous layer allows the implant to fuse to patient bone.

Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for neural network adaptive beamforming for multichannel speech recognition are disclosed. In one aspect, a method includes the actions of receiving a first channel of audio data corresponding to an utterance and a second channel of audio data corresponding to the utterance. The actions further include generating a first set of filter parameters for a first filter based on the first channel of audio data and the second channel of audio data and a second set of filter parameters for a second filter based on the first channel of audio data and the second channel of audio data. The actions further include generating a single combined channel of audio data. The actions further include inputting the audio data to a neural network. The actions further include providing a transcription for the utterance.

Abstract: A sequentially ordered gaming system, kit, or method that allows users to solve a mystery is disclosed, comprising a first objective and a physical package with evidence that enables a user to complete the first objective. A first envelope or other enclosure has a second objective and additional evidence necessary for completion of the second objective, and a second enclosure has a third objective and additional evidence necessary for completion of the third objective. A remote confirmation source is accessed by the user to input specific evidence-related information to determine completion of the objectives and to receive hints. Completion of the first, second, and third objectives in order solves the mystery. The enclosures are typically physical enclosures that are sealed to keep their evidence concealed until use. A final enclosure tells the story of the solved mystery. Evidence includes a combination of a wide variety of materials.

Abstract: A device with a touch-sensitive display and a battery can determine a battery level of the battery, and in accordance with a determination that the battery level is at or below a first threshold value, cause a haptic output and/or enter a low-power mode. While in low-power mode, the device may produce different outputs in response to user inputs than while in a normal power mode. In some embodiments, while in the low-power mode, the device may display only the time and an indication that the device is in a low-power mode.

Abstract: An electronic system (1) comprises an electronic device (2) for gathering data from an inhaler (3) which is configured to dispense doses of a pharmaceutical formulation stored in a medicament reservoir. The system (1) further comprises an evaluation unit (9) being configured to receive and evaluate the gathered data in order to determine adherence to prescription data and/or to determine the number of doses having been dispensed or remaining in the inhaler (3) and a display (8) for visualizing the evaluated data. The electronic device (2) comprises a wireless interface (4) for receiving wireless data from the inhaler (3) via a wireless connection an input interface (5) for receiving manual input data and an acoustic or visual interface (6, 7) for receiving acoustic or visual data of the inhaler (3).

Abstract: An electroplating system has a vessel assembly holding an electrolyte. A weir thief electrode assembly in the vessel assembly includes a plenum inside of a weir frame. The plenum divided into at least a first, a second and a third virtual thief electrode segment. A plurality of spaced apart openings through the weir frame lead out of the plenum. A weir ring is attached to the weir frame and guides flow of current during electroplating. The electroplating system provides process determined radial and circumferential current density control and does not require changing hardware components during set up.

Abstract: A tubing drain with a reusable body and a replaceable sacrificial burst element, the tubing drain comprising an annular body with a window and first and second connector ends, each connector end connectable to an end of tubing sections in a tubing string. The tubing drain also has an inner body insertable into the annular body, the inner body providing the replaceable sacrificial burst element. A burst profile in the inner body aligns with the window in the annular body and provides a burst element which may be configured to burst when a target pressure differential occurs across the burst profile, thereby draining fluids from the tubing string into the casing string.

Abstract: Systems and methods for electroplating are described. The electroplating system may include a vessel configured to hold a first portion of a liquid electrolyte. The system may also include a substrate holder configured for holding a substrate in the vessel. The system may further include a first reservoir in fluid communication with the vessel. In addition, the system may include a second reservoir in fluid communication with the vessel. Furthermore, the system may include a first mechanism configured to expel a second portion of the liquid electrolyte from the first reservoir into the vessel. The system may also include a second mechanism configured to take in a third potion of the liquid electrolyte from the vessel into the second reservoir when the second portion of the liquid electrolyte is expelled from the first reservoir. Methods may include oscillating flow of the electrolyte within the vessel.

Abstract: A distributed acoustic system (DAS) may include an interrogator that includes two or more lasers, a pulser module disposed after and connected to each of the two or more lasers, a wavelength division multiplexer (WDM), wherein each of the pulser modules are connected to the WDM as inputs, and a downhole fiber attached to the WDM as an output and wherein the downhole fiber includes at least one sensing fiber. A method for increasing a sampling frequency may include identifying a length of a downhole fiber connected to an interrogator, generating and launching a light pulse from each of the two or more lasers the pulser module, and delaying an output from the pulser module into the downhole fiber by k/N seconds, where k is a pulse repetition interval of the pulser module and N is equal to the two or more lasers.

Abstract: A mattress system is provided that is optimized for the hospital setting and includes a guiderail system that accepts a variety of accessories for attachment thereto. The guiderail system may have integrated data lines, power lines, gas lines, and/or fluid lines. Also provided are radioabsorbant shields, trays and other components designed for optimal use with the mattress system.

Abstract: The invention relates to a method for determining, diagnosis, prognosis, treatment guidance, treatment monitoring, risk assessment and/or risk stratification of patients with abnormal platelet levels comprising providing a sample of said patient, determining a level of proadrenomedullin (proADM) or fragment(s) thereof in said sample, wherein said level of proADM or fragment(s) thereof correlates with the abnormal platelet levels in said patient. In embodiments of the invention, a level of proADM or fragment(s) thereof of high severity indicates low platelet levels in the subject and subsequent initiating or modifying a treatment of the patient to improve said condition. In some embodiments of the invention the method comprises determining a level of one or more additional markers in a sample isolated from the patient, such as the level of platelets, the level of PCT or fragment(s) thereof, one or more markers of thrombocytopenia and/or one or more markers of an inflammatory response.

Abstract: Methods, systems, and devices for wireless communications are described that provide for selection of different sets of transmission beams by a user equipment (UE) for establishing beamformed communications with a base station. Each transmission beam of a first set of transmission beams may have corresponding uplink random access channel (RACH) resources. A UE may monitor for transmission beams from a base station and select a first transmission beam of the first set for communications with the base station. As part of a connection establishment, the base station may provide configuration information that indicates a second set of transmission beams that includes each transmission beam of the first set of transmission beams and at least an additional transmission beam. In some cases, the additional transmission beam may be mapped to a first RACH resource that also corresponds to a first transmission beam of the first set of transmission beams.

Abstract: A computing system includes processor(s) in a management network that serves an end-user network with agent instances. Server(s), such as a workforce management server or a communication distribution server, receive communications to the end-user network and assign agent instances to service the communications.

Abstract: Methods, systems and storage media for limiting access to one or more of devices and applications for a period of time are disclosed. Some examples may include: receiving electronic assignment information indicating that at least one assignment associated with a user is incomplete, identifying a block of time based on the at least one incomplete assignment and assigning a focus time session to the identified block of time, causing at least one of an application or device to become disabled based on a configuration profile applied during the focus time session, receiving an indication that the at least one incomplete assignment associated with the user has been completed and causing the previously disabled at least one of the application or device to become enabled.

Abstract: Context-specific user interfaces, e.g., for use with a portable multifunction device, provide, inter alia, indications of time and, optionally, a variety of additional information. A user interface screen including a current time indicator and a first platter is displayed. The first platter is at a first position, is associated with a first application, and displays a first set of information obtained from the first application. The first set of information relates to a first temporal context of the current day. In response to detecting a user input, the first platter is displayed at a second position and a second platter is displayed at the first position. The second platter is associated with a second application and displays a second set of information obtained from the second application. The second set of information relates to a second temporal context of the current day.

Abstract: A through the road (TTR) hybridization strategy is proposed to facilitate introduction of hybrid electric vehicle technology in a significant portion of current and expected trucking fleets. In some cases, the technologies can be retrofitted onto an existing vehicle (e.g., a truck, a tractor unit, a trailer, a tractor-trailer configuration, at a tandem, etc.). In some cases, the technologies can be built into new vehicles. In some cases, one vehicle may be built or retrofitted to operate in tandem with another and provide the hybridization benefits contemplated herein. By supplementing motive forces delivered through a primary drivetrain and fuel-fed engine with supplemental torque delivered at one or more electrically-powered drive axles, improvements in overall fuel efficiency and performance may be delivered, typically without significant redesign of existing components and systems that have been proven in the trucking industry.

Abstract: Flexible yet efficient “find” operations search source code for matches to a general pattern after a developer provides an example string that matches the pattern, without requiring the developer to write a regular expression or script that will implement the desired pattern. Example-driven find-replace functionality uses regular expressions or other pattern match codes, and scripts or other transforms, which are synthesized automatically from examples provided by a developer. This technology allows the developer to focus on workflow inside an integrated development environment instead of breaking focus to search for external documentation, or unfortunately foregoing the flexibility and power of regular expressions and scripts. Synthesizer outputs may be directly or indirectly ranked through user feedback, allowing their refinement. Find match generality may be controlled, e.g., by specifying regex star positions or star counts. Entry of guiding examples may be assisted by autocompletion.

Abstract: A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.