Patents by Inventor Wim B. Van Den Berg

Wim B. Van Den Berg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying and isolating cells expressing DC-sign
    Patent number: 7691591
    Abstract: The C-type lectin DC-SIGN is absent in normal synovium but is highly expressed by CD68 positive macrophages in the synovium of rheumatoid arthritis patients. Accordingly, rheumatoid arthritis is diagnosed or treated by, respectively, assaying or blocking DC-SIGN. This can be accomplished by the use of agents, e.g., antibodies, which bind specifically to DCSIGN. Agents that bind to ICAM-3 are used to block inhibition of activation of macrophages by DC-SIGN-ICAM-3 interaction and cause inhibition of rheumatoid arthritis symptoms.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: April 6, 2010
    Assignee: Stichting Katholieke Universiteit
    Inventors: Carl Gustav Figdor, Ruurd Torensma, Petrus Leonardus Everardus Maria Van Lent, Wim B. Van Den Berg