Patents by Inventor Wim Declercq

Wim Declercq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Caspase homologue
    Patent number: 6759227
    Abstract: Caspases are cysteinyl aspartate-specific proteinases, many of which play a central role in apoptosis. This invention relates to the identification of a new murine caspase and its human homologue. The new molecules are most related to human/murine caspase-2 and human caspase-9 and possesses all the typical amino acid residues of the caspases involved in catalysis, including the QACRG box, and contains no or only a very short prodomain. Northern blot analysis revealed that mRNA expression of the new caspase is predominant in skin.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: July 6, 2004
    Assignee: Vlaams Interuniversitair Instituut Voor Biotechnologie VZW
    Inventors: Marc van de Craen, Wim Declercq, Peter Vandenabeele, Walter Fiers
  • Caspase homologue
    Publication number: 20020034812
    Abstract: Caspases are cysteinyl aspartate-specific proteinases, many of which play a central role in apoptosis. This invention relates to the identification of a new murine caspase and its human homologue. The new molecules are most related to human/murine caspase-2 and human caspase-9 and possesses all the typical amino acid residues of the caspases involved in catalysis, including the QACRG box, and contains no or only a very short prodomain. Northern blot analysis revealed that mRNA expression of the new caspase is predominant in skin.
    Type: Application
    Filed: January 17, 2001
    Publication date: March 21, 2002
    Inventors: Marc van de Craen, Wim Declercq, Peter Vandenabeele, Walter Fiers