Patents by Inventor Wim G. J. Hol

Wim G. J. Hol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040136497
    Abstract: A capillary tube (10) is provided with ends that are initially open. The capillary tube (10) is preferably constructed from a plastic material that will allow the contents of the tube (10) to be analyzed by x-raying the tube (10). Plural fluid segments (20, 28, 30, 32) are introduced into the capillary tube (10) through one end of the tube (10). Then, the ends of the capillary tube (10) are closed, such as fusing them shut (34, 36) or by providing them with closure caps (40, 42). Different capillary tubes (10) contain different combinations of the fluid segments. The contents of each capillary tube (10) forms a distinct sample. The samples are viewed and evaluated while they are in the sealed capillary tubes (10).
    Type: Application
    Filed: October 30, 2003
    Publication date: July 15, 2004
    Inventors: Deirdre R. Meldrum, Stewart Turley, Stephen E. Moody, Wim G. J. Hol, Charles H. Fisher
  • Patent number: 6267935
    Abstract: In one aspect, the present invention provides crystallization solutions useful for crystallizing proteins and other molecules, especially macromolecules. In a presently preferred embodiment, the crystallization solutions of the invention are combined as four crystallization solution sets. Each of the four crystallization solution sets includes forty eight different crystallization solutions. Each individual crystallization solution includes a precipitant and a buffer, and optionally includes at least one additive. In another aspect, the present invention provides kits including a plurality of crystallization solutions of the present invention and at least one crystallization plate that preferably includes a plurality of reservoirs. Preferably the crystallization solutions are disposed within the reservoirs of the crystallization plates.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: July 31, 2001
    Assignee: University of Washington
    Inventors: Wim G. J. Hol, Steven H. Sarfaty, Lansing J. Stewart, Hidong Kim