Patents by Inventor Wim Van Den Nest

Wim Van Den Nest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896704
    Abstract: A compound of formula (1) R1—Wm—Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp—Zq—R2, wherein AA1 is Phe; AA2 is Trp; AA3 is selected from Met, Leu and lie; AA4 is selected from Lys, Arg and Gln; AA5 is Arg; AA6 is Lys; AA7 is selected from Arg, Lys and His; AA8 is selected from Val, Ile, Leu and Met; and AA9 is Pro. The compound is useful in the treatment and/or care of the skin, hair, nails and/or mucous membranes, in particular for improving the barrier function of the skin, for energizing the skin and as an anti-aging agent.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 13, 2024
    Assignee: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Raquel Delgado Gonzalez, Núria Almiñana Domènech, Consuelo García Hernández, Mauricio Valerio Santiago, Antonio Ferrer Montiel, Wim Van Den Nest, Catalina Rodríguez Bielsa
  • Patent number: 10799442
    Abstract: Compounds of general formula (I): R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I) their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in processes of treatment and/or care of the skin, hair and/or mucous membranes, in particular in the aging and photoaging of the skin.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: October 13, 2020
    Assignee: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Nuria Alminana Domenech, Wim Van Den Nest, Maria Del Carmen Lidon, Antonio Ferrer Montiel
  • Publication number: 20200214960
    Abstract: A compound of formula (I) R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2, wherein AA1 is Phe; AA2 is Trp; AA3 is selected from Met, Leu and Ile; AA4 is selected from Lys, Arg and Gln; AA5 is Arg; AA6 is Lys; AA7 is selected from Arg, Lys and His; AA8 is selected from Val, Ile, Leu and Met; and AA9 is Pro. The compound is useful in the treatment and/or care of the skin, hair, nails and/or mucous membranes, in particular for improving the barrier function of the skin, for energizing the skin and as an anti-aging agent.
    Type: Application
    Filed: June 5, 2018
    Publication date: July 9, 2020
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Raquel Delgado GONZALEZ, Núria ALMINANA DOMENECH, Consuelo GARClA HERNANDEZ, Mauricio VALERIO SANTIAGO, Antonio FERRER MONTIEL, Wim VAN DEN NEST, Catalina RODRÍGUEZ BIELSA
  • Publication number: 20200046625
    Abstract: A peptide has the formula (I) R1—Wm—Xn-AA1-AA2-AA3-Yp—Zq—R2, where AA1 is Tyr or Trp, AA2 is Val, Ile, Leu or Met, AA3 is Tyr, Phe or Trp, W, X, Y and Z are amino acids, m, n, p and q are each 0 or 1, and m+n+p+q is less than or equal to 2. R1 is H, a polymer derived from polyethylene glycol, a non-cyclic aliphatic group, alicyclyl, heterocyclyl, heteroarylalkyl, aryl, aralkyl, or R5—CO—. R5 is H, a non-cyclic aliphatic group, alicyclyl, aryl, aralkyl, heterocyclyl or heteroarylalkyl. R2 is —NR3R4, —OR3, or —SR3. R3 and R4 are each H, a polymer derived from polyethylene glycol, a non-cyclic aliphatic group, alicyclyl, heterocyclyl, heteroarylalkyl, aryl, or aralkyl. R1 and R2 are not amino acids. Cosmetic or pharmaceutical compositions may include the peptide. It find use in reduction of lipid accumulation in the skin, treatment of cellulite, and treatment of symptoms of skin aging.
    Type: Application
    Filed: October 12, 2017
    Publication date: February 13, 2020
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Wim Van Den Nest, Nuria Almiñana Doménech, Consuelo Garcia, Antonio Vicente Ferrer Montiel
  • Publication number: 20200002377
    Abstract: A compound has a formula (I) R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-(AA7)a-(AA8)b-Yp-Zq-R2, its stereoisomers and/or its cosmetically or pharmaceutically acceptable salts, wherein: AA1 is Glu or replaced by Asp, Gln or Asn, AA2 is Glu or replaced by Asp or Gln; AA3 is Met or replaced by Leu or Ile; AA4 is Gln or replaced by Glu, Asn or Asp; AA5 is Arg or replaced by Lys; AA6 is Arg or replaced by Lys or His; AA7 is Ala, Ser, Gly, Thr, Pro, Glu, Lys, or Val; AA8 is Asp, Glu, Asn, or Gln. In the compound, no more than two of AA1, AA2, AA3, AA4, AA5 and AA6 are replaced, a and b are 0 or 1; W, X, Y and Z are amino acids; m, n, p and q are each 0 or 1; and R1 and R2 are not amino acids. A method of skin treatment with the compound is also described.
    Type: Application
    Filed: November 30, 2017
    Publication date: January 2, 2020
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Wim Van Den Nest, Katalina RODRIGUEZ BIELSA, Olga LAPORTA, Nuria GARCIA SANZ, Nuria ALMIÑANA DOMÈNECH
  • Publication number: 20190184054
    Abstract: Compositions for the treatment of pain and/or inflammation comprising at least one peptide with the general formula (I) R1-AA-R2, its stereoisomers, mixtures thereof, and its cosmetically and pharmaceutically acceptable salts. Peptide with general formula (I), its stereoisomers, mixtures thereof, and its cosmetically and pharmaceutically acceptable salts for the treatment of pain and/or inflammation.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 20, 2019
    Applicant: BCN PEPTIDES, S.A.
    Inventors: Cristina Carreño Serraïma, Wim Van Den Nest, Antonio Ferrer Montiel, Maria Camprubí Robles, Jimena Fernández Carneado, Berta Ponsati Obiols
  • Publication number: 20180369115
    Abstract: Compounds of general formula (I): R1-Wm-Xn-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I) their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in processes of treatment and/or care of the skin, hair and/or mucous membranes, in particular in the aging and photoaging of the skin.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 27, 2018
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: Nuria Alminana Domenech, Wim Van Den Nest, Maria Del Carmen Lidon, Antonio Ferrer Montiel
  • Publication number: 20170101438
    Abstract: A cosmetic or pharmaceutical method for the treatment and/or care of the skin and/or hair which includes administering to the skin and/or hair an effective amount of at least one peptide of general formula (I): R1-AA1-AA2-AA3-R2?? (I) where AA1 and AA2 are independently selected from -Tyr- and -Phe- and AA3 is selected from -Nle- and -Met-, its stereoisomers, mixtures thereof and/or cosmetically or pharmaceutically acceptable salts thereof, in the treatment and/or care of conditions, disorders and/or diseases of the skin and/or hair by stimulating cyclic adenosine monophosphate synthesis (cAMP).
    Type: Application
    Filed: December 22, 2016
    Publication date: April 13, 2017
    Inventors: Núria GARCÍA SANZ, Wim VAN DEN NEST, Cristina CARREÑO SERRAÏMA, Antonio Vicente FERRER MONTIEL, Juan CEBRIÁN PUCHE, Núria ALMlÑANA DOMENECH
  • Patent number: 9511010
    Abstract: Compounds of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2??(I) their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in processes of treatment and/or care of the skin, hair and/or mucous membranes, in particular in the aging and photoaging of the skin, are described.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: December 6, 2016
    Assignee: Lubrizol Advanced Materials, Inc.
    Inventors: Wim Van Den Nest, Cristina Carreño Serraïma, Raquel Delgado González, Antonio Vicente Ferrer Montiel
  • Patent number: 9464129
    Abstract: The invention relates to peptides of general formula (I): R1-AA-R2??(I) which can regulate neuronal exocytosis, their stereoisomers and racemic or non-racemic mixtures thereof, and the cosmetically or pharmaceutically acceptable salts thereof, wherein AA is a sequence of 3 to 40 adjacent amino acids contained in the amino acid sequence of the SNAP-25 protein, R1 is selected from the group consisting of H or alkyl, aryl, aralkyl or acyl group; and R2 is selected from the group consisting of amino, hydroxyl or thiol, substituted or non-substituted with aliphatic or cyclic groups, with the condition that when R1 is H or acetyl, R2 is not non-substituted amino, hydroxyl or thiol. The invention also relates to a method of obtaining such peptides, cosmetic or pharmaceutical compositions containing them and their use to treat those conditions requiring neuronal exocytosis regulation, preferably for treating the skin.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: October 11, 2016
    Assignee: BCN PEPTIDES S.A.
    Inventors: Cristina Carreño Serraïma, Berta Ponsati Obiols, Wim Van Den Nest, Jimena Fernandez Carneado, Antonio Ferrer Montiel, Juan Cebrian Puche, Nuria Almiñana Domenech
  • Patent number: 9458194
    Abstract: Compounds of general formula (I): their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in the treatment and/or care of the skin, particularly in the aging and photoaging of the skin, and more particularly for the treatment and/or prevention of wrinkles and/or stretch marks.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: October 4, 2016
    Assignee: Lubrizol Advanced Materials, Inc.
    Inventors: Antonio Vicente Ferrer Montiel, Núria Almiñana Doménech, Juan Cebrián Puche, Wim Van Den Nest, Cristina Carreño Serraïma, Raquel Delgado González
  • Patent number: 9315564
    Abstract: Peptides of general formula (I): R1AA1-AA2-AA3-AA4-R2 stereoisomers thereof, mixtures thereof or the cosmetically or pharmaceutically acceptable salts thereof, a method for obtaining them, cosmetic or pharmaceutical compositions containing them, and their use for the treatment and/or care of those conditions, disorders and/or pathologies of the skin, mucosae and/or scalp resulting from matrix metalloproteinases (MMP) overexpression or an increase in the MMP activity.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: April 19, 2016
    Assignee: Lipotec, S.A.
    Inventors: Cristina Carreño Serraïma, Wim Van Den Nest, Juan Cebri{dot over (a)}n Puche, Nuria Almiñana Domenech, Antonio Ferrer Montiel, Nuria Garcia Sanz
  • Publication number: 20160075738
    Abstract: Compounds of general formula (I): their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in the treatment and/or care of the skin, particularly in the aging and photoaging of the skin, and more particularly for the treatment and/or prevention of wrinkles and/or stretch marks.
    Type: Application
    Filed: April 15, 2014
    Publication date: March 17, 2016
    Inventors: Antonio Vicente FERRER MONTIEL, Núria ALMIÑANA DOMÉNECH, Juan CEBRIÁN PUCHE, Wim VAN DEN NEST, Cristina CARREÑO SERRAÏMA, Raquel DELGADO GONZÁLEZ
  • Publication number: 20150342852
    Abstract: Compounds of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2; their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, cosmetic and/or pharmaceutical compositions which contain them and their use in medicine, and in processes of treatment and/or care of the skin, hair and/or mucous membranes, in particular in the aging and photoaging of the skin.
    Type: Application
    Filed: December 3, 2013
    Publication date: December 3, 2015
    Inventors: Wim Van Den Nest, Cristina Carreño Serraïma, Raquel Delgado González, Antonio Vicente Ferrer Montiel
  • Publication number: 20150183823
    Abstract: Cosmetic or pharmaceutical compositions and methods employ peptides of general formula (I): R1-AA1-AA2-AA3-R2,??(I) where AA1 is selected from -Tyr- and -Phe-, AA2 is -Tyr-, and AA3 is selected from -Nle- and -Met-, its stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, in the treatment and/or care of conditions, disorders and/or diseases of the skin and/or hair by stimulating cyclic adenosine monophosphate synthesis (cAMP).
    Type: Application
    Filed: March 10, 2015
    Publication date: July 2, 2015
    Inventors: Núria GARCÍA SANZ, Wim VAN DEN NEST, Cristina CARREÑO SERRAÏMA, Antonio Vicente FERRER MONTIEL, Juan CEBRIÁN PUCHE, Núria ALMIÑANA DOMENECH
  • Patent number: 8993716
    Abstract: Peptides of general formula (I): R1—Wn—Xm-AA1-AA2-AA3-AA4-Yp—Zq—R2 (I) its stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, a preparation process, cosmetic or pharmaceutical compositions which contain them and their use in the treatment and/or care of the skin, mucous membranes and/or hair and the treatment and/or care of those conditions, disorders and/or diseases which are improved or prevented by Hsp stimulation.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: March 31, 2015
    Assignees: Lipotec, S.A., BCN Peptides, S.A.
    Inventors: Cristina Carreño Serraïma, Wim Van Den Nest, Ana Sempere Bonete, Antonio Ferrer Montiel, Nuria Almiñana Domenech, Juan Cebrián Puche
  • Patent number: 8946166
    Abstract: Peptides of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zs-R2 their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, their preparation process, cosmetic or pharmaceutical compositions which contain them and their use in the treatment and/or care of conditions, disorders and/or diseases that are a consequence of muscle contraction.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: February 3, 2015
    Assignee: Lipotec, S.A.
    Inventors: Nuria Garcia Sanz, Wim Van Den Nest, Cristina Carreno Serraima, Antonio Ferrer Montiel, Juan Cebrian Puche, Nuria Alminana Domenech, Gregorio Fernandez Ballester
  • Patent number: 8815266
    Abstract: The invention relates to peptide derivatives of general formula (I): R1-AA1-AA2-R3-AA4-R2??(I) their stereoisomers, mixtures thereof, and their cosmetically or pharmaceutically acceptable salts, a method for obtaining them, cosmetic or pharmaceutical compositions containing them and their use for the treatment, care and/or cleansing of those conditions, disorders and/or pathologies of the skin, mucosae, scalp and/or nails resulting from microorganism proliferation or being at risk of microorganism proliferation.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 26, 2014
    Assignees: Lipotech, S.A., Diverdrugs, S.L, Puig, S.A.
    Inventors: Cristina Carreño Serraïma, Wim Van Den Nest, Ana Sempere Bonete, Antonio Ferrer Montiel, Juan Cebrián Puche, Nuria Alminaña Doménech, David Panyella Costa, José Ginestar González
  • Patent number: 8710011
    Abstract: Peptides of general formula (I): R1-Wp-Xn-AA1-AA2-AA3-AA4-Ym-R2 their stereoisomers, mixtures thereof, and/or their cosmetically or pharmaceutically acceptable salts, a method of preparation, cosmetic or pharmaceutical compositions containing them and their use for the treatment, prevention and/or care of conditions, disorders and/or diseases of the skin, mucous membranes and/or scalp.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: April 29, 2014
    Assignee: Lipotec, S.A.
    Inventors: Nuria Garcia Sanz, Wim Van Den Nest, Cristina Carreno Serraima, Antonio Ferrer Montiel, Juan Cebrian Puche, Nuria Alminana Domenech
  • Patent number: 8710010
    Abstract: Peptides with general formula (I): R1-AA1-AA2-AA3-AA4-R2 its stereoisomers, mixtures thereof, and its cosmetically or pharmaceutically acceptable saits, a method of preparation, cosmetic or pharmaceutical compositions containing them and their use for the treatment and/or care of conditions, disorders and/or pathologies of the skin, mucous membranes, scalp and/or hair.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: April 29, 2014
    Assignee: Lipotec, S.A.
    Inventors: Wim Van Den Nest, Nuria Almiñana Domenech, Juan Cebrián Puche, Cristina Carreño Serraïma