Abstract: An apparatus for intraorgan administration of medicinal agents, such as, cells, growth factors, drugs and other agents under direct visualization, for example using an endoscope, by an apparatus and method which create needle channels within the target organ and deposits by injection, the medicinal agent in high concentrations at designated sites of the target organ. The device consists of a chamber having at least one retractable hollow bore needle; a reservoir for containing an injectable medicinal agent which is in communication with the needle and control means for extending and retracting the needle from and into the chamber and forcing the medicinal agent from the reservoir into the needle and injecting it into a target organ, said control means being suitable for effecting control through an endoscopic tube. Also disclosed are injection needles having side openings therein for enhanced administration of the medicinal agent to the target organ.