Patents by Inventor Winfried Stephan Wels

Winfried Stephan Wels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant antibodies specific for a growth factor receptor
    Patent number: 5939531
    Abstract: The invention concerns recombinant antibodies directed to the extracellular domain of the human growth factor receptor c-erbB-2 comprising a light chain variable domain and a heavy chain variable domain of a monoclonal antibody, monoclonal antibodies directed to c-erbB-2 themselves, a method of manufacture of said recombinant antibodies and said monoclonal antibodies, hybridoma cells secreting said monoclonal antibodies, a method of manufacture of said hybridoma cells, DNA coding for the heavy chain variable domain, for the light chain variable domain and for the recombinant antibody, a method of manufacture of said DNA, hybrid vectors suitable for expression of said DNA, host cells transformed with said DNA, and the use of said recombinant antibodies and said monoclonal antibodies in the diagnosis and treatment of tumors.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 17, 1999
    Assignee: Novartis Corp.
    Inventors: Winfried Stephan Wels, Nancy E. Hynes, Ina-Maria Harwerth, Bernd Groner, Norman Hardman, Markus Zwickl