Abstract: Provided herein are methods, compositions, kits, and systems for the detection of neutralization targets such as neutralizing antibodies.

Abstract: Disclosed herein is a fast voltage stabilizer wherein an actual voltage across a targeted electronic element is sensed. The actual voltage is compared with a reference voltage. A control signal is generated, wherein in response to the control signal, an external current path is provided to maintain current flow and stabilize the actual voltage through charging or discharging an input capacitor and a supply filtering capacitor. Under an arbitrary supply voltage variation, a fast dynamic response to regulate the voltage across the targeted electronic element is provided no matter what the operating mode of the entire electrical circuit is, including but not limited by constant current mode, constant output resistant mode and constant power mode.

Abstract: A current control circuit having a current regulation element, a first control circuit, and a second control circuit. The first control circuit is arranged to regulate, based on a reference current, a current flowing with respect to the current regulation element. The second control circuit is arranged to regulate, based on a reference voltage, a voltage across the current regulation element.

Abstract: An electric circuit arrangement and a method for generating electric current pulses to a load, the electric circuit arrangement including a switch and a current source in series connection with the load; wherein the switch is arranged to operate in at least an on state and an off state, thereby selectively connecting or disconnecting the current source to or from the load so as to generate the electric current pulses. With such architecture, the circuit performs with a better efficiency than a cascaded architecture.

Abstract: The present invention provides methods for determining a haplotype or a diplotype in a genetic sample. The method comprises the steps of contacting a probe-complex with the genetic sample, wherein the probe complex comprises at least two probes, hybridizing at least two probes to a polynucleotide sequence, each of which is specific to one of two or more genetic variants, determining the presence or absence of at least one genetic variant by detecting a signal emitted from at least one probe, wherein detection of said signal is indicative of the the presence of a genetic variant, removing or displacing at least one of said probes from said sample, and detecting a change in the signal to determine the haplotype or a diplotype in the genetic sample. Kits for use in the method of the invention are also provided.

Abstract: A current control circuit having a current regulation element, a first control circuit, and a second control circuit. The first control circuit is arranged to regulate, based on a reference current, a current flowing with respect to the current regulation element. The second control circuit is arranged to regulate, based on a reference voltage, a voltage across the current regulation element.

Abstract: An electric circuit arrangement and a method for generating electric current pulses to a load, the electric circuit arrangement including a switch and a current source in series connection with the load; wherein the switch is arranged to operate in at least an on state and an off state, thereby selectively connecting or disconnecting the current source to or from the load so as to generate the electric current pulses. With such architecture, the circuit performs with a better efficiency than a cascaded architecture.

Abstract: A power factor correction circuit for a power electronic system includes a series-pass device arranged to control an input characteristic of a power converter, and a control mechanism arranged to control an operation of the series-pass device during a power conversion process. The correction circuit increases a power factor of the power electronic system and/or reduces a harmonic distortion generated by the power converter to an electrical current supplied by a power source in the power electronic system.

Abstract: A current control apparatus arranged to regulate an electric current flowing between a load and an external electric circuit includes a current control loop having a current regulator arranged to manipulate an amount of the electric current flowing between the load and the external electric circuit; and a voltage control loop having a voltage regulator arranged to manipulate a voltage across the current regulator.

Abstract: An input filter for a power electronic system includes a series-pass device arranged to control an input characteristic of a power converter, and a control mechanism arranged to control an operation of the series-pass device during a power conversion process, so as to filter a noise signal generated by the power converter from reaching a power source of the power electronic system.

Abstract: An input filter for a power electronic system includes a series-pass device arranged to control an input characteristic of a power converter, and a control mechanism arranged to control an operation of the series-pass device during a power conversion process, so as to filter a noise signal generated by the power converter from reaching a power source of the power electronic system.

Abstract: A power factor correction circuit for a power electronic system comprising a series-pass device arranged to control an input characteristic of a power converter, and a control mechanism arranged to control an operation of the series-pass device during a power conversion process, so as to increase a power factor of the power electronic system and/or to reduce a harmonic distortion generated by the power converter to an electrical current supplied by a power source in the power electronic system.