Patents by Inventor Wing Yip Lam

Wing Yip Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220180882
    Abstract: A method of training an audio separation network is provided. The method includes obtaining a first separation sample set, the first separation sample set including at least two types of audio with dummy labels, obtaining a first sample set by performing interpolation on the first separation sample set based on perturbation data, obtaining a second separation sample set by separating the first sample set using an unsupervised network, determining losses of second separation samples in the second separation sample set, and adjusting network parameters of the unsupervised network based on the losses of the second separation samples, such that a first loss of a first separation result outputted by an adjusted unsupervised network meets a convergence condition.
    Type: Application
    Filed: February 28, 2022
    Publication date: June 9, 2022
    Applicant: TENCENT TECHNOLOGY(SHENZHEN) COMPANY LIMITED
    Inventors: Jun WANG, Wing Yip Lam, Dan Su, Dong Yu
  • Publication number: 20220172707
    Abstract: A speech recognition method includes: obtaining first sample speech data corresponding to a target user and a first reference speech recognition result corresponding to the first sample speech data; obtaining a pre-update target model; inputting the first sample speech data into the pre-update target model, and performing speech recognition by using a target speech extraction model, a target feature extraction model, and a target speech recognition model, to obtain a first model output result; obtaining a target model loss value corresponding to the target feature extraction model according to the first model output result and the first reference speech recognition result; and updating a model parameter of the target feature extraction model in the pre-update target model according to the target model loss value, to obtain a post-update target model.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Inventors: Jun WANG, Wing Yip LAM
  • Publication number: 20220148571
    Abstract: This application relates to a speech recognition method and apparatus, and a computer-readable storage medium, and the method includes: obtaining a first loss function of a speech separation and enhancement model and a second loss function of a speech recognition model; performing back propagation based on the second loss function to train an intermediate model bridged between the speech separation and enhancement model and the speech recognition model, to obtain a representation model; fusing the first loss function and the second loss function, to obtain a target loss function; and jointly training the speech separation and enhancement model, the representation model, and the speech recognition model based on the target loss function, and ending the training when a preset convergence condition is met.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 12, 2022
    Applicant: Tencent Technology (Shenzhen) Company Limited
    Inventors: Jun WANG, Wing Yip LAM
  • Publication number: 20220004870
    Abstract: This application provides a speech recognition and apparatus and a neural network training method and apparatus, and relates to the field of Artificial Intelligence (AI) technologies. The neural network training method is performed by an electronic device and includes: obtaining sample data, the sample data including a mixed speech spectrum and a labeled phoneme thereof; extracting a target speech spectrum from the mixed speech spectrum by using a first subnetwork; adaptively transforming the target speech spectrum by using a second subnetwork, to obtain an intermediate transition representation; performing phoneme recognition based on the intermediate transition representation by using a third subnetwork; and updating parameters of the first subnetwork, the second subnetwork, and the third subnetwork according to a result of the phoneme recognition and the labeled phoneme.
    Type: Application
    Filed: September 15, 2021
    Publication date: January 6, 2022
    Inventors: Jun WANG, Wing Yip LAM, Dan SU, Dong YU
  • Patent number: 11118111
    Abstract: The present subject matter relates to a fluorescent compound having aggregation-induced emission (AIE) characteristics. The compound can be a rod-like chiral luminogen bearing a chiral moiety at one end and long aliphatic chains at an opposing end. The compound emits circularly polarized light or luminescence (CPL) in the aggregate state. For example, the compound does not exhibit a chiroptical signal when dispersed in solution, but demonstrates tunable CPL signals in the aggregate state.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: September 14, 2021
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Wing Yip Lam, Fengyan Song
  • Publication number: 20210153801
    Abstract: Methods for screening, diagnosing, or predicting presence, progression, or treatment effects of a cognitive dysfunction such as dementia based on an analysis of drawing behavior changes by a pre-trained Naïve Bayes method are provided. The methods include steps of obtaining drawing data of at least one image created by a test subject on a digital device and obtaining personal data of the test subject; reconstructing the at least one image based on the drawing data obtained; converting the drawing data to drawing features comprising a plurality of motion features and a plurality of geometric features; and determining probability that the test subject has a cognitive dysfunction based on the drawing features and the personal data by a pre-trained Naïve Bayes method with a greedy variable selection.
    Type: Application
    Filed: November 26, 2019
    Publication date: May 27, 2021
    Inventors: Kam Fai Tsoi, Wing Yip Lam, Tsz Kan Christopher Chu, Ka Ho Tsang
  • Publication number: 20200157425
    Abstract: The present subject matter relates to a fluorescent compound having aggregation-induced emission (AIE) characteristics. The compound can be a rod-like chiral luminogen bearing a chiral moiety at one end and long aliphatic chains at an opposing end. The compound emits circularly polarized light or luminescence (CPL) in the aggregate state. For example, the compound does not exhibit a chiroptical signal when dispersed in solution, but demonstrates tunable CPL signals in the aggregate state.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 21, 2020
    Inventors: Benzhong TANG, Wing Yip LAM, Fengyan SONG
  • Patent number: 9929363
    Abstract: The present subject matter relates to compositions containing and synthesis of fluorescent materials e made from tetraphenylethylene (TPE) derivative compounds exhibiting aggregation induced emission (AIE) properties. Further contemplated herein are applications for TPE derivative compounds such as electroluminescent devices since they have a high efficiency, low turn on voltage, and excellent brightness. Additionally, application of TPE derivatives exhibiting AIE properties in various fields such as OLEDs, fingerprinting and forensic technology, and various other biological and industrial sectors are discussed.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: March 27, 2018
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Ni Xie, Wing Yip Lam
  • Patent number: 9618453
    Abstract: Provided herein are fluorescent bioprobes comprising fluorogens that exhibit aggregation-induced emission (AIE) labeled on biomolecules. The present subject matter relates to a fluorescent bioprobe comprising one or more fluorogen labeled on chitosan. The present subject matter is also directed to methods of preparing the fluorescent bioprobes, methods of labeling and detecting DNA and/or proteins with the fluorescent bioprobe, and methods of cell imaging including live cell tracking.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: April 11, 2017
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Ka Ming Ng, Qian Luo, Yong Yu, Yuning Hong, Jianzhao Liu, Sijie Chen, Wing Yip Lam, Zhengke Wang, Wei Qin, Tsz Kin Kwok
  • Patent number: 9518921
    Abstract: Provided herein are magnetic silica fluorescent nanoparticles and fluorescent silica nanoparticles comprising an aggregation induced emission luminogen and magnetite nanoparticles and use of the same as a fluorescent bioprobe for intracellular imaging and a protein carrier. Also provided are processes for preparing and fabricating the same.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: December 13, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Wing Yip Lam, Jianzhao Liu, Faisal Mahtab, Yang Liu, Yong Yu
  • Patent number: 9475768
    Abstract: Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: October 25, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Yang Liu, Wing Yip Lam, Yong Yu
  • Patent number: 9409928
    Abstract: Fluorescent bioprobes comprising luminogen formed nanoparticles comprising luminogens with aggregation-induced emission (AIE) properties, which can be used for long-term cell tracking. The luminogens are nonemissive in organic solution but become highly emissive when aggregated in aqueous solution. The fluorescent molecules can readily pass through cell membranes, stain only the cell cytoplasm, and form highly emissive nanoaggregates in aqueous media without any obvious cytoxicity in the living cells. Furthermore, the molecules can be retained inside the cells without noticeable leakage to the outside. Therefore, these AIE-based compounds can be used as selective and cell-compatible fluroescent bioprobes for long-term live cell tracking and imaging.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: August 9, 2016
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Ka Ming Ng, Qian Luo, Yong Yu, Yuning Hong, Jianzhao Liu, Sijie Chen, Wing Yip Lam
  • Publication number: 20160211470
    Abstract: The present subject matter relates to compositions containing and synthesis of fluorescent materials e made from tetraphenylethylene (TPE) derivative compounds exhibiting aggregation induced emission (AIE) properties. Further contemplated herein are applications for TPE derivative compounds such as electroluminescent devices since they have a high efficiency, low turn on voltage, and excellent brightness. Additionally, application of TPE derivatives exhibiting AIE properties in various fields such as OLEDs, fingerprinting and forensic technology, and various other biological and industrial sectors are discussed.
    Type: Application
    Filed: August 5, 2014
    Publication date: July 21, 2016
    Inventors: Benzhong TANG, Ni XIE, Wing Yip LAM
  • Patent number: 9200121
    Abstract: A poly(siloxane-diphenylbutadiyne) exhibiting thermosetting properties, a highly tunable glass transition temperature (Tg), and very high thermal and thermo-oxidative stability. In one embodiment, the poly(siloxane-diphenylbutadiyne) is a poly(tetrasiloxane-diphenylbutadiyne). The present subject matter also relates to a method of synthesizing the poly(tetrasiloxane-diphenylbutadiyne).
    Type: Grant
    Filed: April 7, 2013
    Date of Patent: December 1, 2015
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong Tang, Jie Li, Rongrong Hu, Wing Yip Lam
  • Patent number: 9109155
    Abstract: The development of a series of fluorescent materials including heterocycle-functionalized luminogens with aggregation-induced/enhanced emission (AIE/AEE), long wavelength emission, and high solid state fluorescence quantum efficiency is contemplated. The described fluorescent materials are promising candidates in selective luminescence-based chemosensor for Hg2+ or ATP, fluorescent staining for mitochondria in living cells with high photostability, stimuli-responsive luminescent materials, and materials for optical waveguides. In addition, these heterocycle-functionalized luminogens are particularly useful as fluorescent labels for biopolymers such as peptides, antibodies, or nucleic acids, making them useful as AIE-active biocompatible probes for clinical cancer imaging and diagnostics.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: August 18, 2015
    Assignees: The Hong Kong University of Science and Technology, National University of Singapore
    Inventors: Benzhong Tang, Wing Yip Lam, Na Zhao, Min Li, Bin Liu, Haibin Shi, Dan Ding
  • Publication number: 20150057421
    Abstract: A poly(siloxane-diphenylbutadiyne) exhibiting thermosetting properties, a highly tunable glass transition temperature (Tg), and very high thermal and thermo-oxidative stability. In one embodiment, the poly(siloxane-diphenylbutadiyne) is a poly(tetrasiloxane-diphenylbutadiyne). The present subject matter also relates to a method of synthesizing the poly(tetrasiloxane-diphenylbutadiyne).
    Type: Application
    Filed: April 7, 2013
    Publication date: February 26, 2015
    Inventors: Benzhong Tang, Jie Li, Rongrong Hu, Wing Yip Lam
  • Publication number: 20140348753
    Abstract: The development of a series of fluorescent materials including heterocycle-functionalized luminogens with aggregation-induced/enhanced emission (AIE/AEE), long wavelength emission, and high solid state fluorescence quantum efficiency is contemplated. The described fluorescent materials are promising candidates in selective luminescence-based chemosensor for Hg2+ or ATP, fluorescent staining for mitochondria in living cells with high photostability, stimuli-responsive luminescent materials, and materials for optical waveguides. In addition, these heterocycle-functionalized luminogens are particularly useful as fluorescent labels for biopolymers such as peptides, antibodies, or nucleic acids, making them useful as AIE-active biocompatible probes for clinical cancer imaging and diagnostics.
    Type: Application
    Filed: May 24, 2013
    Publication date: November 27, 2014
    Inventors: Benzhong TANG, Wing Yip LAM, Na ZHAO, Min LI, Bin LIU, Haibin SHI, Dan DING
  • Patent number: 8859698
    Abstract: A sulfur-containing macromolecule and a method of preparing the sulfur-containing macromolecule comprising a polymerization step are provided, where the sulfur-containing macromolecule contains internal units of formula (I) and the polymerization step is formula (II) wherein n is greater than 1, said precursor comprises alkyne having one or more acetylene groups and thiol having one or more thiol groups; and R is remainder of said thiol excluding said thiol groups, R? is remainder of said alkyne excluding said acetylene groups, and R and R? are selected from organic or organometallic groups.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: October 14, 2014
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Benzhong Tang, Ka Wai Jim, Anjun Qin, Wing Yip Lam, Jianzhao Liu
  • Publication number: 20140255696
    Abstract: Fluorescent silica nanoparticles with aggregation induced emission characteristics as well as methods for attaching biotin thereto for tumor cell targeting and long-term cell tracking. Additionally, dendrimers decorated with AIR fluorogens.
    Type: Application
    Filed: March 20, 2014
    Publication date: September 11, 2014
    Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong TANG, Wing Yip LAM, Min LI, Mathieu ARSENEAULT
  • Patent number: 8524858
    Abstract: Provided is a high temperature-resistant metal adhesive containing hyperbranched poly(triazole)s synthesized by in situ azide/alkyne click polymerization. Also provided is a method for preparing the same adhesives by in situ click polymerization of azide and alkyne monomers on metal substrates. The method is optimized to get high adhesive strength at room temperature or elevated temperatures by analyzing the effects of monomer ratio, curing temperature and time, and annealing temperature and time. The hyberbranched poly(triazole)s adhesive has comparable or better temperature resistance compared with known high temperature epoxy metal adhesives, and it is the first high temperature metal adhesive using hyperbranched poly(triazole)s prepared by in situ azide/alkyne click polymerization.
    Type: Grant
    Filed: January 5, 2011
    Date of Patent: September 3, 2013
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Benzhong Tang, Youhong Tang, Ka Wai Jim, Anjun Qin, Wing Yip Lam, Jie Li