Patents by Inventor Winston Ong

Winston Ong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of a therapeutic compound and uses thereof
    Patent number: 10253045
    Abstract: Disclosed herein are certain crystalline forms of Compound 5, N-(5-((2-(4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butanamido)imidazo[1,2-0]pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-1/-/-pyrazole-5-carboxamide, as well as pharmaceutical compositions comprising the crystalline forms. The present disclosure further relates to methods for treating or preventing diseases or disorders using the crystalline forms or pharmaceutical compositions thereof in a subject in need thereof, including diseases or disorders associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor signaling pathway (e.g., vascular endothelial growth factor (VEGF)), such as proliferative diseases and ocular diseases.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: April 9, 2019
    Assignee: Kala Pharmaceuticals, Inc.
    Inventors: Tadeas Liska, Elizabeth Enlow, Jinsoo Kim, Winston Ong
  • CRYSTALLINE FORMS OF A THERAPEUTIC COMPOUND AND USES THEREOF
    Publication number: 20170313724
    Abstract: Disclosed herein are certain crystalline forms of Compound 5, N-(5-((2-(4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butanamido)imidazo[1,2-0]pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-1/-/-pyrazole-5-carboxamide, as well as pharmaceutical compositions comprising the crystalline forms. The present disclosure further relates to methods for treating or preventing diseases or disorders using the crystalline forms or pharmaceutical compositions thereof in a subject in need thereof, including diseases or disorders associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor signaling pathway (e.g., vascular endothelial growth factor (VEGF)), such as proliferative diseases and ocular diseases.
    Type: Application
    Filed: November 24, 2015
    Publication date: November 2, 2017
    Inventors: Tadeas Liska, Elizabeth Enlow, Jinsoo Kim, Winston Ong
  • Crystalline forms of therapeutic compounds and uses thereof
    Patent number: 9458169
    Abstract: Described herein is certain crystalline forms of Compound 3, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: October 4, 2016
    Assignee: Kala Pharmaceuticals, Inc.
    Inventors: Elizabeth Enlow, Minh Ngoc Nguyen, Winston Ong
  • CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF
    Publication number: 20150125535
    Abstract: Described herein is certain crystalline forms of Compound 3, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions.
    Type: Application
    Filed: October 31, 2014
    Publication date: May 7, 2015
    Inventors: Elizabeth Enlow, Mint Ngoc Nguyen, Winston Ong