Abstract: Small molecules acting through the ligand binding domain of nuclear receptor TLX (NR2E1) are disclosed, as well as the use thereof for promoting neurogenesis and treating disorders associated with nuclear receptor TLX, including neurological disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula II as described herein, and pharmaceutically acceptable salts or isomers thereof.

Abstract: Acoustic volume indicators of this invention comprise a resonator for causing a liquid container to vibrate, a detector for receiving vibration data from the liquid container, a frequency detector for converting the vibration data to frequency and comparing the frequency to stored frequency v. volume data to obtain the liquid volume, and an indicator for providing a desired output based on the liquid volume. The resonator can be provided in the form of an impactor that is actuated to strike the side of the liquid container to momentarily vibrate the tank, or in the form of a vibration generator that is operated to generate a sweep frequency signal in the tank. The detector is designed to respond to vibration signals provided from the tank wall, which signals will show a significant increase in amplitude at the resonant frequency of the tank and its contents. The detector can be in the form of an accelerometer designed to record the received signal.

Abstract: Acoustic volume indicators for determining liquid or gas volume within a container comprise a contactor to vibrate a container wall, a detector to receive vibration data from the container wall, a processor to convert vibration data to frequency information and compare the frequency information to characteristic container frequency vs. volume data to obtain the measured volume, and an indicator for displaying the measured volume. The processor may comprise a microprocessor disposed within a housing having lights that each represent a particular volume. The microprocessor is calibrated to provide an output signal to a light that indicates the container volume. The processor may comprise a computer and computer program that converts the data to frequency information, analyzes the frequency information to identify a peak frequency, compares the peak frequency to the characteristic frequency vs. volume data to determine the measured volume, and displays the measured volume on a video monitor.

Abstract: A bladder surge tank includes a liquid port, and a bladder disposed therein for providing a surge absorbing interface between liquid and pressurized gas within the tank. The bladder surge tank can be horizontally or vertically oriented. In a horizontal embodiment, the surge tank includes a nozzle system disposed horizontally therein that is separate from the liquid port and that is integrally joined to the interior wall. Such nozzle system includes a nozzle member positioned between the liquid port and the bladder, and comprises a plurality of perforations disposed therethrough. In a vertical embodiment, the surge tank includes a nozzle system disposed vertically therein that is part of the liquid port and that includes a nozzle member having a plurality of perforations disposed therethrough.