Patents by Inventor Wiro M. P. B. Menge

Wiro M. P. B. Menge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazolone derivatives as PDE4 inhibitors
    Patent number: 9090597
    Abstract: The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase useful in the treatment of psoriasis or atopic dermatitis.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: July 28, 2015
    Assignee: Takeda GmbH
    Inventors: Beate Schmidt, Christian Scheufler, Jürgen Volz, Martin Feth, Rolf-Peter Hummel, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Deborah Ockert, Anke Heuser, Johannes A. M. Christiaans, Geert Jan Sterk, Wiro M. P. B. Menge
  • PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS
    Publication number: 20140378509
    Abstract: The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase useful in the treatment of psoriasis or atopic dermatitis.
    Type: Application
    Filed: August 29, 2014
    Publication date: December 25, 2014
    Inventors: Beate SCHMIDT, Christian SCHEUFLER, Jürgen VOLZ, Martin FETH, Rolf-Peter HUMMEL, Armin HATZELMANN, Christof ZITT, Andrea WOHLSEN, Degenhard MARX, Hans-Peter KLEY, Deborah OCKERT, Anke HEUSER, Johannes A.M. CHRISTIAANS, Geert Jan STERK, Wiro M.P.B. MENGE
  • Pyrazolone derivatives as PDE4 inhibitors
    Patent number: 8865745
    Abstract: The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: October 21, 2014
    Assignee: Takeda GmbH
    Inventors: Beate Schmidt, Christian Scheufler, Juergen Volz, Martin Feth, Rolf-Peter Hummel, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Deborah Ockert, Anke Heuser, Johannes A. M. Christiaans, Geert Jan Sterk, Wiro M. P. B. Menge
  • PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS
    Publication number: 20130012544
    Abstract: The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Applicant: NYCOMED GMBH
    Inventors: Beate SCHMIDT, Christian SCHEUFLER, Jürgen VOLZ, Martin FETH, Rolf-Peter HUMMEL, Armin HATZELMANN, Christof ZITT, Andrea WOHLSEN, Degenhard MARX, Hans-Peter KLEY, Deborah OCKERT, Anke HEUSSR, Johannes A.M. CHRISTIAANS, Geert Jan STERK, Wiro M.P.B. MENGE
  • Pyrazolone derivatives as PDE4 inhibitors
    Patent number: 8304436
    Abstract: The compounds of a certain formula 1, in which R1, R7, R8, R9 and n have the meanings as given in the description, are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: November 6, 2012
    Assignee: Nycomed GmbH
    Inventors: Beate Schmidt, Christian Scheufler, Juergen Volz, Martin Feth, Rolf-Peter Hummel, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Deborah Ockert, Anke Heuser, Johannes A. M. Christiaans, Geert Jan Sterk, Wiro M. P. B. Menge
  • 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
    Patent number: 7820669
    Abstract: The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: October 26, 2010
    Assignee: NYCOMED GmbH
    Inventors: Wiro M. P. B. Menge, Geert Jan Sterk
  • PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS
    Publication number: 20100120757
    Abstract: The compounds of a certain formula 1, in which R1, R7, R8, R9 and n have the meanings as given in the description, are novel effective inhibitors of the type 4 phosphodiesterase.
    Type: Application
    Filed: May 14, 2008
    Publication date: May 13, 2010
    Applicant: NYCOMED GmbH
    Inventors: Beate Schmidt, Christian Scheufler, Juergen Volz, Martin Feth, Rolf-Peter Hummel, Armin Hatzelmann, Christof Zitt, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley, Deborah Ockert, Anke Heuser, Johannes A.M. Christiaans, Geert Jan Sterk, Wiro M.P.B. Menge
  • 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2,3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS
    Publication number: 20100120730
    Abstract: The compounds of formula (I) wherein R1 to R8 and R11 have the meanings as given in the description, the salts thereof, the N-oxides of the compounds and the salts thereof, and the stereoisomers of the compounds, the salts, the N-oxides of the compounds and the N-oxides of the salts thereof are effective inhibitors of the type 5 phosphodiesterase.
    Type: Application
    Filed: January 30, 2008
    Publication date: May 13, 2010
    Applicant: NYCOMED GmbH
    Inventors: Steffen Weinbrenner, Torsten Dunkern, Degenhard Marx, Beate Schmidt, Thomas Stengel, Dieter Flockerzi, Ulrich Kautz, Daniela Hauser, Jörg Diefenbach, Johannes A.M. Christiaans, Wiro M.P.B. Menge
  • 2-(Piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
    Publication number: 20090131448
    Abstract: The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: January 14, 2009
    Publication date: May 21, 2009
    Applicant: NYCOMED GmbH
    Inventors: Wiro M. P. B. Menge, Geert Jan Sterk
  • 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
    Patent number: 7494990
    Abstract: The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: February 24, 2009
    Assignee: NYCOMED GmbH
    Inventors: Wiro M. P. B. Menge, Geert Jan Sterk
  • Pyridazinone Derivatives and their Use as Pde4 Inhibitors
    Publication number: 20080227790
    Abstract: The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: February 1, 2005
    Publication date: September 18, 2008
    Applicant: Altana Pharma AG
    Inventors: Wiro M.P.B. Menge, Geert Jan Sterk
  • Novel flavonoids
    Publication number: 20020147353
    Abstract: Novel flavonoids of formula (I) 1
    Type: Application
    Filed: March 22, 2002
    Publication date: October 10, 2002
    Applicant: Vereniging christelijk wetenschappelijk anderwijs
    Inventors: Willem J.F. Van Der Vijgh, Aalt Bask, Frederique A.A. Van Acker, Wiro M.P.B. Menge, Guido R.M.M. Haenen