Patents by Inventor Wiro Menge

Wiro Menge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making duocarmycin prodrugs
    Patent number: 9890159
    Abstract: The present invention relates to a process comprising converting a compound of formula (I) into a compound of formula (II) by reaction with an organolithium reagent, which compound can be further converted into duocarmycin analogs consisting of a DNA-alkylating and a DNA-binding part, and still further into corresponding antibody-drug conjugates.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: February 13, 2018
    Assignee: Synthon Biopharmaceuticals B.V.
    Inventors: Tijl Huijbregts, Ronald Christiaan Elgersma, Patrick Henry Beusker, Johannes Albertus Frederikus Joosten, Rudy Gerardus Elisabeth Coumans, Henri Johannes Spijker, Wiro Menge, Franciscus Marinus Hendrikus De Groot
  • 2-(Piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
    Publication number: 20070179146
    Abstract: The compounds of a certain formula 1, in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
    Type: Application
    Filed: February 1, 2005
    Publication date: August 2, 2007
    Applicant: Atlanta Pharma AG
    Inventors: Wiro Menge, Geert Sterk