Patents by Inventor Witold Bula

Witold Bula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10027855
    Abstract: A line confocal microscope system, comprising a scanning unit in the form of a mechanically driven scanning unit with a controllable a scanning trajectory and a two dimensional sensor unit operated in a rolling line shutter mode in synchronization with the scanning unit, wherein the scanning trajectory is set to have an acceleration part outside the field of view of the sensor unit.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: July 17, 2018
    Assignee: GE HEALTHCARE BIO-SCIENCE CORP.
    Inventors: Witold Bula, Pavel A. Fomitchov, Steve Goodson, Erwen Mei, Yang Zhang
  • Patent number: 9373158
    Abstract: The present invention relates to a system and method for reducing image artifacts for a CMOS camera used as an optical detector for a line confocal fluorescent imager. The method for reducing image artifacts in a monochromatic image comprises subtracting RGB channel offset mismatch; and correcting random row offset for each row. Preferably, the method also comprises correcting random column offset and gain. Optionally, the method also comprises clipping of defective pixels, and/or subtracting dark current. When the monochromatic image is a fluorescence image, the method also comprises a step of compressing CMOS camera noise. Also provided are a system for reducing image artifacts in a monochromatic image from a CMOS camera, as well as an image artifact reduction system for a CMOS camera-based line confocal fluorescent microscope.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: June 21, 2016
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Pavel A. Fomitchov, Witold Bula, Carlos Zarate, Yang Zhang
  • Publication number: 20140152800
    Abstract: Microscopy system for biological imaging, comprising an image quality optimizer for optimizing image quality of an image of a biological sample, allowing a user to select an optimization mode from a list of functionally defined optimization modes, and wherein the system is arranged to automatically set one or more image acquisition parameters to achieve optimal imaging for the selected optimization mode based on at least one image quality parameter derived from one or more Biological Reference Objects (BRO) in the image of the biological sample selected by the user or automatically by the system.
    Type: Application
    Filed: June 27, 2012
    Publication date: June 5, 2014
    Applicant: GE Healthcare Bio-Sciences Corp.
    Inventors: Pavel A. Fomitchov, Witold Bula
  • Publication number: 20140140595
    Abstract: Microscopy system for biological imaging, comprising an image quality monitoring system for monitoring image quality of an image of a biological sample comprising a biological object selection means arranged to let a user of the system to select one or more Biological Reference Objects (BRO) in the image of the biological sample, and an image quality evaluation means arranged to compare the signal level of image pixels of the one or more BROs with an image background signal level to calculate one or more image quality parameters for the image of the biological sample. The system is arranged to present the image quality parameters to the user as an indication of the image quality specific for the BRO(s).
    Type: Application
    Filed: June 27, 2012
    Publication date: May 22, 2014
    Applicant: GE Healthcare Bio-Sciences Corp.
    Inventors: Pavel A. Fomitchov, Witold Bula
  • Publication number: 20130129212
    Abstract: The present invention relates to a system and method for reducing image artifacts for a CMOS camera used as an optical detector for a line confocal fluorescent imager. The method for reducing image artifacts in a monochromatic image comprises subtracting RGB channel offset mismatch; and correcting random row offset for each row. Preferably, the method also comprises correcting random column offset and gain. Optionally, the method also comprises clipping of defective pixels, and/or subtracting dark current. When the monochromatic image is a fluorescence image, the method also comprises a step of compressing CMOS camera noise. Also provided are a system for reducing image artifacts in a monochromatic image from a CMOS camera, as well as an image artifact reduction system for a CMOS camera-based line confocal fluorescent microscope.
    Type: Application
    Filed: July 19, 2011
    Publication date: May 23, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventors: Pavel A. Fomitchov, Witold Bula, Carlos Zarate, Yang Zhang
  • Publication number: 20130093873
    Abstract: A line confocal microscope system, comprising a scanning unit in the form of a mechanically driven scanning unit with a controllable a scanning trajectory and a two dimensional sensor unit operated in a rolling line shutter mode in synchronization with the scanning unit, wherein the scanning trajectory is set to have an acceleration part outside the field of view of the sensor unit.
    Type: Application
    Filed: June 29, 2011
    Publication date: April 18, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventors: Witold Bula, Pavel A. Fomitchov, Steve Goodson, Erwen Mei, Yang Zhang