Patents by Inventor Wlodzimierz Zagorski

Wlodzimierz Zagorski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA VACCINE, METHOD OF INDUCING THE IMMUNE RESPONSE, METHOD OF IMMUNISATION, ANTIBODIES SPECIFICALLY RECOGNISING THE H5 HAEMAGGLUTININ OF AN INFLUENZA VIRUS AND USE OF THE DNA VACCINE
    Publication number: 20140255343
    Abstract: The object of the invention is a DNA vaccine, method of inducing the immune response, antibodies specifically recognising the haemagglutinin H5 of an influenza virus and application of the DNA vaccine. According to the invention, one or two-fold immunisation of hens with DNA vaccine containing a cDNA encoding the modified H5 haemagglutinin HA protein, i.e. with the deletion of the cleavage site between HA subunits (this provides for greater safety of the vaccines). Moreover, the encoding region of the HA is modified in such a way that protein production in the bird cells should achieve maximal yield. The main modification is codon optimisation for the hens and deletion of the site of proteolytic cleavage between subunits HA1 and HA2.
    Type: Application
    Filed: September 21, 2012
    Publication date: September 11, 2014
    Inventors: Agnieszka Sirko, Anna Gora-Sochacka, Wlodzimierz Zagorski-Ostoja, Anna Stachyra, Roza Sawicka, Boguslaw Szewczyk, Beata Gromadzka, Violetta Saczynska, Katarzyna Florys, Zenon Minta, Krzysztof Smietanka
  • Cell-proliferation inhibiting VPg proteins, fragments or analogs thereof and their applications
    Patent number: 8324150
    Abstract: Use of VPg proteins, fragments or analogs thereof having the ability to bind an eukaryotic initiation factor eIF4E, for inhibiting cell-proliferation.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: December 4, 2012
    Assignees: Centre National de la Recherche Scientifique, Institute of Biochemistry and Biophysics—Polish Academy of Sciences, Universite Joseph Fourier
    Inventors: Jadwiga Chroboczek, Wlodzimierz Zagorski, Renata Grzela
  • Derivatives of epirubicin, their medicinal application and pharmaceuticaly acceptable forms of drugs
    Patent number: 8173610
    Abstract: The present invention relates to novel derivatives of epirubicin, pharmaceutical composition comprising these derivatives, and uses of epirubicin and its derivative for treating HCV.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: May 8, 2012
    Assignees: Instytut Biochemii I Biofizyki, Institut National de Las Sante Et de la Recherche Medicale (Inserm), Instytut Medycyny Doswiadczalnej I Kliniczne
    Inventors: Tadeusz Kulikowski, Maria Bretner, Andzelika Najda, Lucyna Cova, Christian Trepo, Ramamurthy Narayan, Andrzej Piasek, Andrzej Lipniacki, Wlodzimierz Zagorski-Ostoja
  • CELL-PROLIFERATION INHIBITING VPG PROTEINS, FRAGMENTS OR ANALOGS THEREOF AND THEIR APPLICATIONS
    Publication number: 20100160234
    Abstract: Use of VPg proteins, fragments or analogs thereof having the ability to bind an eukaryotic initiation factor eIF4E, for inhibiting cell-proliferation.
    Type: Application
    Filed: June 13, 2008
    Publication date: June 24, 2010
    Inventors: Jadwiga Chroboczek, Wlodzimierz Zagorski, Renata Grzela
  • DERIVATIVES OF EPIRUBICIN, THEIR MEDICINAL APPLICATION AND PHARMACEUTICALY ACCEPTABLE FORMS OF DRUGS
    Publication number: 20090247623
    Abstract: The present invention relates to novel derivatives of epirubicin, pharmaceutical composition comprising these derivatives, and uses of epirubicin and its derivative for treating HCV.
    Type: Application
    Filed: November 14, 2006
    Publication date: October 1, 2009
    Applicants: INSTYTUT MEDYCYNY DOSWIADCZALNEJ I KLINICZNEJ, INSTYTUT BIOCHEMII I BIOFIZYKI, Institut National De La Sante Et De La Recherche Medicale
    Inventors: Tadeusz Kulikowski, Maria Bretner, Andzelika Najda, Lucyna Cova, Christian Trepo, Ramamurthy Narayan, Andrzej Piasek, Andrzej Lipniacki, Wlodzimierz Zagorski-Ostoja