Patents by Inventor Wojciech J. Czestkowski

Wojciech J. Czestkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 10538508
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: January 21, 2020
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal L. Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20190345137
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: February 15, 2019
    Publication date: November 14, 2019
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal L. Kowalski
  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 10208020
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: February 19, 2019
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elżbieta Maziarz, Michal Łukasz Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20180258071
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: February 28, 2018
    Publication date: September 13, 2018
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal Lukasz Kowalski
  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 9944624
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: April 17, 2018
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michał C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elżbieta Maziarz, Michał Łukasz Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20170066743
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: September 2, 2016
    Publication date: March 9, 2017
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal Lukasz Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS
    Publication number: 20160368894
    Abstract: Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.
    Type: Application
    Filed: September 1, 2016
    Publication date: December 22, 2016
    Inventors: Adam A. Golebiowski, Robert Koralewski, Wojciech J. Czestkowski, Krzysztof Matyszewski, Sylwia Olejniczak, Jacek P. Olczak, R. Paul Beckett
  • Substituted amino triazoles useful as acidic mammalian chitinase inhibitors
    Patent number: 9440953
    Abstract: Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: September 13, 2016
    Assignee: OncoArendi Therapeutics Sp. z o.o.
    Inventors: Adam Golebiowski, Robert Koralewski, Wojciech J. Czestkowski, Krzysztof Matyszewski, Sylwia Olejniczak, Jacek Olczak, Paul Beckett
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS
    Publication number: 20160176843
    Abstract: Disclosed are amino triazole compounds substituted by a carboxylate functional group or an bioisosteric polar functional group. Compounds having the carboxylate moiety or carboxylate bioisostere inhibit acidic mammalian chitinase. Also provided are methods of using the compounds to treat asthma reactions caused by allergens.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 23, 2016
    Inventors: Adam Golebiowski, Robert Koralewski, Wojciech J. Czestkowski, Krzysztof Matyszewski, Sylwia Olejniczak, Jacek Olczak, Paul Beckett