Patents by Inventor Wojciech Kasprzak

Wojciech Kasprzak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functionally-interdependent shape switching nucleic acid nanoparticles
    Patent number: 11512313
    Abstract: The description provides a molecular switch comprising at least two nanoparticles, wherein a first nanoparticle comprises DNA and/or RNA oligonucleotides, and a second nanoparticle which is complementary to the first nanoparticle comprises reverse complementary DNA and/or RNA oligonucleotides of the first nanoparticle; wherein the complementary nanoparticles interact under physiological conditions leading to thermodynamically driven conformational changes in the first and second nanoparticles leading to their re-association to release one or more duplexes comprising said DNA and/or RNA oligonucleotides and the reverse complementary DNA and/or RNA oligonucleotides, and wherein the nanoparticles are not rings and have no single stranded toeholds.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: November 29, 2022
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The University of North Carolina at Charlote
    Inventors: Bruce Allen Shapiro, Kirill Andreevich Afonin, Eckart H. U. Bindewald, Mathias D. Viard, Wojciech Kasprzak, Marina A. Dobrovolskaia, Justin R. Halman
  • FUNCTIONALLY-INTERDEPENDENT SHAPE SWITCHING NUCLEIC ACID NANOPARTICLES
    Publication number: 20200199587
    Abstract: The description provides a molecular switch comprising at least two nanoparticles, wherein a first nanoparticle comprises DNA and/or RNA oligonucleotides, and a second nanoparticle which is complementary to the first nanoparticle comprises reverse complementary DNA and/or RNA oligonucleotides of the first nanoparticle; wherein the complementary nanoparticles interact under physiological conditions leading to thermodynamically driven conformational changes in the first and second nanoparticles leading to their re-association to release one or more duplexes comprising said DNA and/or RNA oligonucleotides and the reverse complementary DNA and/or RNA oligonucleotides, and wherein the nanoparticles are not rings and have no single stranded toeholds.
    Type: Application
    Filed: April 3, 2018
    Publication date: June 25, 2020
    Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, The University of North Carolina at Charlotte
    Inventors: Bruce Allen Shapiro, Kirill Andreevich Afonin, Eckart H.U. Bindewald, Mathias D. Viard, Wojciech Kasprzak, Marina A. Dobrovolskaia, Justin R. Halman
  • RNA nanoparticles and nanotubes
    Patent number: 9732337
    Abstract: The instant invention provides polyvalent RNA nanoparticles comprising RNA motifs as building blocks that can form RNA nanotubes. The polyvalent RNA nanoparticles are suitable for therapeutic or diagnostic use in a number of diseases or disorders.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: August 15, 2017
    Assignees: The United Stated of America, as represented by the Secretary, Department of Health & Human Services, The Regents of the University of California
    Inventors: Bruce A. Shapiro, Yaroslava G. Yingling, Eckart Bindewald, Wojciech Kasprzak, Luc Jaeger, Isil Severcan, Cody Geary, Kirill Afonin
  • RNA NANOPARTICLES AND NANOTUBES
    Publication number: 20120263648
    Abstract: The instant invention provides polyvalent RNA nanoparticles comprising RNA motifs as building blocks that can form RNA nanotubes. The polyvalent RNA nanoparticles are suitable for therapeutic or diagnostic use in a number of diseases or disorders.
    Type: Application
    Filed: June 16, 2010
    Publication date: October 18, 2012
    Applicants: REGENTS OF THE UNIVERSITY OF CALIFORNIA, SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Bruce A. Shapiro, Yaroslava G. Yingling, Eckart Bindewald, Wojciech Kasprzak, Luc Jaeger, Isil Severcan, Cody Geary, Kirill Afonin
  • Electromagnetic method and apparatus for treatment of engineering materials, products, and related processes
    Patent number: 7255828
    Abstract: A method and apparatus for performing electromagnetic treatment on engineering materials and products and for improving processing technologies and service characteristics of the materials. The apparatus integrates electromagnetic treatment with a thermal analyzer and a control system. The apparatus allows for precise control of the operating parameters of an electromagnetic treatment process in order to render significant improvement in the materials and products metallurgical characteristics.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: August 14, 2007
    Inventors: Marcin Stanislaw Kasprzak, Wojciech Kasprzak, Jerzy H. Sokolowski
  • Method and apparatus for universal metallurgical simulation and analysis
    Publication number: 20050151306
    Abstract: A method and apparatus (5) for simulating and analyzing industrial thermal processes, including industrial heat-treatment, processes, melting, solidification, quenching and the like, used in the manufacture of metals, alloys and metal matrix composite components. The apparatus (5) includes an optional environmental chamber (10) used for situations where testing room conditions are too hot or too cold and would thus interfere with operation of the apparatus (5) without such chamber (10). The apparatus (5) includes a multifunctional excitation coil (40) that serves the function of the omitted environmental chamber (10). The apparatus (5) also includes one or more high frequency resonant inverters (15) and a cooling means (20). The apparatus (5) integrates melting and thermal processing capabilities with a thermal analyzer and a control system.
    Type: Application
    Filed: December 12, 2002
    Publication date: July 14, 2005
    Inventors: Jerzy Sokolowski, Witold Kierkus, Marcin Kasprzak, Wojciech Kasprzak
  • Electromagnetic method and apparatus for treatment of engineering materials, porducts, and related processes
    Publication number: 20040108630
    Abstract: A method and apparatus for performing electromagnetic treatment on engineering materials and products and for improving processing technologies and service characteristics of the materials. The apparatus integrates electromagnetic treatment with a thermal analyzer and a control system. The apparatus allows for precise control of the operating parameters of an electromagnetic treatment process in order to render significant improvement in the materials and products metallurgical characteristics.
    Type: Application
    Filed: December 5, 2003
    Publication date: June 10, 2004
    Inventors: Marcin Stanislaw Kasprzak, Wojciech Kasprzak, Jerzy H. Sokolowski