Patents by Inventor Wojtek Auerbach

Wojtek Auerbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for generating an animal homozygous for a genetic modification
    Patent number: 7294754
    Abstract: Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant or complete contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: November 13, 2007
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: William Poueymirou, Thomas M. Dechiara, Wojtek Auerbach, David Frendewey, David M. Valenzuela
  • Method for generating an animal homozygous for a genetic modification
    Publication number: 20060085866
    Abstract: Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant or complete contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 20, 2006
    Inventors: William Poueymirou, Thomas Dechiara, Wojtek Auerbach, David Frendewey, David Valenzuela
  • Methods for identifying a cell or an embryo carrying a Y chromosome
    Publication number: 20060064770
    Abstract: Methods for modifying a mammalian cell target such that the presence of a Y chromosome is detectable. The method includes construction of a targeting vector with a detectable marker that can recombine or insert into a pre-selected site on the Y chromosome, allowing the presence of the Y chromosome to be detectable through the presence of the integrated detectable marker. The method can be used to distinguish male from female embryos.
    Type: Application
    Filed: September 15, 2005
    Publication date: March 23, 2006
    Inventors: David Frendewey, Wojtek Auerbach, Thomas Dechiara, David Valenzuela
  • Method of improving gene targeting using a ubiquitin promoter
    Publication number: 20050101017
    Abstract: Methods of improving gene targeting comprising using a ubiquitin promoter to drive drug resistance gene expression are provided. Such improvements include increasing ES cell colony survival and targeting frequency.
    Type: Application
    Filed: November 10, 2003
    Publication date: May 12, 2005
    Inventors: Wojtek Auerbach, David Frendewey, Andrew Murphy, David Valenzuela