Patents by Inventor Wolf-Dieter Schleuning

Wolf-Dieter Schleuning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE
    Publication number: 20170051268
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Application
    Filed: March 24, 2016
    Publication date: February 23, 2017
    Inventors: Mariola SOHNGEN, Wolfgang SOHNGEN, Wolf-Dieter SCHLEUNING, Robert MEDCALF
  • NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE
    Publication number: 20140199287
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 17, 2014
    Applicant: H. LUNDBECK A/S
    Inventors: Mariola SOHNGEN, Wolfgang SOHNGEN, Wolf-Dieter SCHLEUNING, Robert MEDCALF
  • NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE
    Publication number: 20130039902
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Application
    Filed: February 10, 2012
    Publication date: February 14, 2013
    Applicant: H. Lundbeck A/S
    Inventors: Mariola Sohngen, Wolfgang Sohngen, Wolf-Dieter Schleuning, Robert Medcalf
  • Non-neurotoxic plasminogen activating factors for treating of stroke
    Patent number: 8119597
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: February 21, 2012
    Assignee: Paion GmbH
    Inventors: Mariola Sohngen, Wolfgang Sohngen, Wolf-Dieter Schleuning, Robert Medcalf
  • Non-neurotoxic plasminogen activating factors for treating stroke
    Patent number: 8071091
    Abstract: The invention pertains to the use and production of non-neurotoxic plasminogen activating factors e.g. of Desmodus rotundus (DSPA) for the therapeutic treatment of stroke in humans in order to provide a new therapeutic concept for treating stroke in humans.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: December 6, 2011
    Assignee: Paion Deutschland GmbH
    Inventors: Robert Medcalf, Mariola Söhngen, Wolfgang Söhngen, Wolf-Dieter Schleuning
  • ORAL MODIFIED RELEASE FORMULATIONS
    Publication number: 20100086599
    Abstract: This invention is directed to an oral modified release formulation of the phytoestrogen 8-Prenylnaringenin in combination with a progestin, preferably with Drospirenone, and several uses thereof. In another aspect of the invention an oral modified formulation of 8-Prenylnaringenin with an immediately releasing progestin, like Drospirenone, is provided as well as several uses thereof.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 8, 2010
    Applicant: KAIROSMED GMBH
    Inventors: Michael Huempel, Wolf Dieter Schleuning, Arno Heuermann, Matthias Krings, Markus Thunecke, Johannes Tack
  • NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE
    Publication number: 20090263373
    Abstract: The invention concerns the use and the production of non-neurotoxic plasminogen activating factors, derived, for example, from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Application
    Filed: August 22, 2008
    Publication date: October 22, 2009
    Inventors: Mariola SOHNGEN, Wolfgang Sohngen, Wolf-Dieter Schleuning, Robert Medcalf
  • NON-NEUROTOXIC PLASMINOGEN ACTIVATING FACTORS FOR TREATING OF STROKE
    Publication number: 20090004176
    Abstract: The invention pertains to the use and production of non-neurotoxic plasminogen activating factors e.g. of Desmodus rotundus (DSPA) for the therapeutic treatment of stroke in humans in order to provide a new therapeutic concept for treating stroke in humans.
    Type: Application
    Filed: June 27, 2008
    Publication date: January 1, 2009
    Inventors: Robert MEDCALF, Mariola Sohngen, Wolfgang Sohngen, Wolf-Dieter Schleuning
  • Use of 8-Prenylnaringenin for Hormone Replacement Therapy
    Publication number: 20070276032
    Abstract: The invention provides a production method for the phytoestrogen 8-Prenylnaringenin, the preparation produced by this method and the use of 8-Prenylnaringenin for the production of a medicament for the prevention and treatment of hormone-dependent osteoporosis and of peri- and postmenopausal symptoms in women.
    Type: Application
    Filed: October 6, 2004
    Publication date: November 29, 2007
    Inventors: Michael Huempel, Wolf-Dieter Schleuning, Olaf Schaefer, Paivi Isaksson, Rolf Bohlmann
  • Thrombin-inhibiting peptides
    Publication number: 20070042959
    Abstract: Peptides of Formula I are useful for therapeutic purposes, among others.
    Type: Application
    Filed: September 19, 2006
    Publication date: February 22, 2007
    Inventors: Christiane Noeske-Jungblut, Ursula Egner, Peter Donner, Wolf-Dieter Schleuning, Wolfram Bode, Pablo Fuentes Prior
  • Method for identifying a pharmacologically active substance
    Publication number: 20050106592
    Abstract: Method for identifying a novel biologically active substance, which is based on defining the targeted property of the substance and selecting a reference organism, naturally displaying the targeted property.
    Type: Application
    Filed: August 17, 2004
    Publication date: May 19, 2005
    Inventors: Wolf-Dieter Schleuning, Torsten Schulz
  • Non-neurotoxic plasminogen activating factors for treating stroke
    Publication number: 20050048027
    Abstract: The invention concerns the use and the production of non-neurotoxin plasminogen activating factors, derived for example from the common vampire Desmodus rotundus (DSPA), for therapeutic treatment of stroke in humans. The invention provides a novel therapeutic base for treating stroke in humans.
    Type: Application
    Filed: October 31, 2002
    Publication date: March 3, 2005
    Inventors: Mariola Sohngen, Wolfgang Sohngen, Wolf-Dieter Schleuning, Robert Medcalf
  • Thrombin-inhibiting peptides
    Publication number: 20040147442
    Abstract: Peptides of Formula I are useful for therapeutic purposes, among others.
    Type: Application
    Filed: October 29, 2003
    Publication date: July 29, 2004
    Inventors: Christiane Noeske-Jungblut, Ursula Egner, Peter Donner, Wolf-Dieter Schleuning, Wolfram Bode, Pablo Fuentes Prior
  • Method for identifying a pharmacologically active substance
    Publication number: 20030203373
    Abstract: Method for identifying a novel biologically active substance, which is based on defining the targeted property of the substance and selecting a reference organism, naturally displaying the targeted property.
    Type: Application
    Filed: July 24, 2002
    Publication date: October 30, 2003
    Inventors: Wolf-Dieter Schleuning, Torsten Schulz
  • Urokinase-type plasminogen activator receptor
    Publication number: 20030027981
    Abstract: A polypeptide presenting an epitope cross-reactive with an epitope of urokinase-type plasminogen activator receptor, and/or having uPA binding activity, is described.
    Type: Application
    Filed: January 8, 2001
    Publication date: February 6, 2003
    Inventors: Keld Dano, Francesco Blasi, Ann Louring Roldan, Maria Vittoria Cubellis, Maria Teresa Masucci, Ettore Appella, Wolf-Dieter Schleuning, Niels Behrendt, Ebbe Ronne, Peter Kristensen, Jari Pollanen, Eeva-Marjatta Salonen, Ross W. Stephens, Hannele Tapiovaara, Antti Vaheri, Lisbeth Birk Moller, Vincent Ellis, Leif Roge Lund, Michael Ploug, Charles Pyke, Laszlo Patthy
  • Plasminogen activator from saliva of the vampire bat
    Patent number: 6008019
    Abstract: The present invention relates to novel thrombolitic v-PA's which dissolve blood clots in the human body and thus are suitable for the treatment of cardial infarction, for example.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 28, 1999
    Assignee: Schering Aktiengesellschaft
    Inventors: Berthold Baldus, Peter Donner, Wolf-Dieter Schleuning, Alejandro Alagon, Werner Boidol, Jorn Reiner Kratzschmar, Bernard Jacques Haendler, Gernot Langer
  • Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
    Patent number: 5891664
    Abstract: Activation of plasminogen to plasma is inhibited by preventing the binding of a receptor binding form of urokinase-type plasminogen activator to a urokinase-type plasminogen activator receptor in a mammal, thereby preventing the urokinase-type plasminogen activator from converting plasminogen into plasmin. DNA fragments which encode for soluble, active fragments of the urokinase-type plasminogen activator are provided.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: April 6, 1999
    Assignee: Cancerforskningsfondet af 1989
    Inventors: Keld Dan.o slashed., Francesco Blasi, Ann Louring Roldan, Maria Vittoria Cubellis, Maria Teresa Masucci, Ettore Appella, Wolf-Dieter Schleuning, Niels Behrendt, Ebbe R.o slashed.nne, Peter Kristensen, Jari Pollanen, Eeva-Marjatta Salonen, Ross W. Stephens, Hannele Tapiovaara, Antti Vaheri, Lisbeth Birk M.o slashed.ller, Vincent Ellis, Leif R.o slashed.ge Lund, Michael Ploug, Charles Pyke, Laszlo Patthy
  • Thrombin inhibitor from the saliva of protostomia
    Patent number: 5876971
    Abstract: The invention relates to a natural protein or a protein that can be synthetically produced, which is a thrombin inhibitor and can be isolated from the saliva of insects which suck the blood of mammals. Preferred is the Triatoma pallidipennis insect. The protein is used for the treatment of thromboses or unstable angina or arteriosclerosis, or for the prevention of a reblockage of vessels after PTCA/PTA or for the prevention of blood clotting in hemodialysis.
    Type: Grant
    Filed: August 24, 1995
    Date of Patent: March 2, 1999
    Assignee: Schering Aktiengesellschaft
    Inventors: Christiane Noeske-Jungblut, Wolf-Dieter Schleuning, Alejandro Alagon, Lourival Possani, Delia Cuevas-Aguierre, Peter Donner, Bernard Haendler, Ulrike Hechler
  • Collagen-induced platelet aggregation inhibitor
    Patent number: 5756454
    Abstract: The invention provides a protein which inhibits collagen-induced platelet aggregation, derived from Triatoma pallidipennis, and derivatives thereof. The protein is useful for inhibition of collagen-induced human platelet aggregation or of cancer with metastatic tumor cells.
    Type: Grant
    Filed: March 7, 1994
    Date of Patent: May 26, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Christiane Noeske-Jungblut, Bernard Haendler, Joern Reiner Kraetzschmar, Wolf-Dieter Schleuning, Alejandro Alagon, Lourival Possani, Delia Cuevas-Aguirre
  • Collagen-induced platelet aggregation inhibitor
    Patent number: 5723312
    Abstract: The invention provides a protein which inhibits collagen-induced platelet aggregation, derived from Triatoma pallidipennis, and derivatives thereof. The protein is useful for inhibition of collagen-induced human platelet aggregation or of cancer with metastatic tumor cells.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 3, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Christiane Noeske-Jungblut, Bernard Haendler, Joern Reiner Kraetzschmar, Wolf-Dieter Schleuning, Alejandro Alagon, Lourival Possani, Delia Cuevas-Aguirre