Patents by Inventor Wolf KLÖCKNER

Wolf KLÖCKNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11788107
    Abstract: The invention relates to a method for producing aniline or an aniline derivative, in which a solution of aminobenzoic acid in aniline with a mass fraction of aniline in the solution, in relation to the total mass of aminobenzoic acid and aniline, in the region of 20% to 85%, is subject to a thermal decarboxylation at a temperature in the region of 165° C. to 500° C. without the presence of a non-system catalyst, such that the aminobenzoic acid is converted into aniline. The obtained aniline can be converted into derivatives, such as di- and polyamines of the diphenylmethane series.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: October 17, 2023
    Assignee: Covestro Intellectual Property Gmbh & Co. Kg
    Inventors: Jens Langanke, Franz Beggel, Gernot Jaeger, Wolf Kloeckner, Volker Michele, Thomas Voessing
  • Patent number: 11597901
    Abstract: Disclosed herein is a sterilizable adapter for a cell culture vessel comprising a body, an upper connection and/or a lid, at least one port, a ventilation passage, a lower internal connection suitable for connection to a cell culture vessel and a cell retention device and/or a cell separation device as well as a device comprising said sterilizable adapter and a method for cell cultivation using said sterilizable adapter.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: March 7, 2023
    Assignees: Bayer Aktiengesellschaft, BAYER HEALTHCARE LLC
    Inventors: Annette Eidt, Wolf Kloeckner, Helmut Brod, Martin Poggel, Bernd Tscheschke
  • Patent number: 11453897
    Abstract: The invention relates to a method for producing aminobenzoic acid or an aminobenzoic acid derivative using a fermentation process, in which (I) the aminobenzoic acid formed in the fermentation broth obtained by the fermentation is bound in part, or as much as possible based on the solubility equilibrium, as insoluble calcium-aminobenzoate, said insoluble calcium-aminobenzoate is then (II) either isolated as such or in a mixture with the microorganism used in the fermentation and transitioned into a water soluble form, while separating an insoluble calcium salt which is different from the calcium-aminobenzoate, and then (III) by introducing carbon dioxide under pressure into the aqueous solution from the precipitated calcium salt has been released, aminobenzoic acid is precipitated.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: September 27, 2022
    Assignee: Covestro Intellectual Property GmbH & Co. KG
    Inventors: Gernot Jaeger, Guenter Olf, Franz Beggel, Wolf Kloeckner, Simon Klaff
  • Patent number: 11168341
    Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 9, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Patent number: 11155844
    Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 26, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Amgad Salah Moussa, Simon Klaffl, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Publication number: 20210277346
    Abstract: Disclosed herein is a sterilizable adapter for a cell culture vessel comprising a body, an upper connection and/or a lid, at least one port, a ventilation passage, a lower internal connection suitable for connection to a cell culture vessel and a cell retention device and/or a cell separation device as well as a device comprising said sterilizable adapter and a method for cell cultivation using said sterilizable adapter.
    Type: Application
    Filed: July 19, 2017
    Publication date: September 9, 2021
    Inventors: Annette EIDT, Wolf KLOECKNER, Helmut BROD, Martin POGGEL, Bernd TSCHESCHKE
  • Publication number: 20210238638
    Abstract: The invention relates to a method for producing aniline or an aniline derivative, in which a solution of aminobenzoic acid in aniline with a mass fraction of aniline in the solution, in relation to the total mass of aminobenzoic acid and aniline, in the region of 20% to 85%, is subject to a thermal decarboxylation at a temperature in the region of 165° C. to 500° C. without the presence of a non-system catalyst, such that the aminobenzoic acid is converted into aniline. The obtained aniline can be converted into derivatives, such as di- and polyamines of the diphenylmethane series.
    Type: Application
    Filed: July 24, 2019
    Publication date: August 5, 2021
    Inventors: Jens Langanke, Franz Beggel, Gernot Jaeger, Wolf Kloeckner, Volker Michele, Thomas Voessing
  • Publication number: 20210222215
    Abstract: The invention relates to a method for producing aminobenzoic acid or an aminobenzoic acid derivative using a fermentation process, in which (I) the aminobenzoic acid formed in the fermentation broth obtained by the fermentation is bound in part, or as much as possible based on the solubility equilibrium, as insoluble calcium-aminobenzoate, said insoluble calcium-aminobenzoate is then (II) either isolated as such or in a mixture with the microorganism used in the fermentation and transitioned into a water soluble form, while separating an insoluble calcium salt which is different from the calcium-aminobenzoate, and then (III) by introducing carbon dioxide under pressure into the aqueous solution from the precipitated calcium salt has been released, aminobenzoic acid is precipitated.
    Type: Application
    Filed: June 5, 2019
    Publication date: July 22, 2021
    Inventors: Gernot Jaeger, Guenter Olf, Franz Beggel, Wolf Kloeckner, Simon Klaffl
  • Publication number: 20200263213
    Abstract: The present invention relates to methods for increasing the concentration of anthranilic acid tolerated by a given microbial cell by limiting the concentration of ammonia in the culture medium.
    Type: Application
    Filed: October 12, 2018
    Publication date: August 20, 2020
    Inventors: Gernot JÄGER, Wolf KLOECKNER, Swantje BEHNKEN, Simon KLAFFL, Jamaleddine SASSI
  • Publication number: 20200239832
    Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using microbial cells and alkali-containing bases during fermentation
    Type: Application
    Filed: October 12, 2018
    Publication date: July 30, 2020
    Inventors: Gernot JÄGER, Wolf KLOECKNER, Swantje BEHNKEN, Simon KLAFFL, Jamaleddine SASSI
  • Patent number: 10279327
    Abstract: An orbital shaker with a balancing device that automatically and passively compensates, without supply of external energy, forces and moments which are caused by imbalance and arise during operation, in particular as a result of a possible variable loading (mass, geometry of the containers, properties of the contents) and variable operating parameters (speed of rotation and shaking radius). The balancing device can be designed such that only the unbalance forces (static balancing) and/or the unbalance moments (dynamic balancing) are compensated.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: May 7, 2019
    Assignee: ADOLF KÜHNER AG
    Inventors: Burkhard Corves, Mathias Schumacher, Jochen Büchs, Wolf Klöckner
  • Publication number: 20180371512
    Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
    Type: Application
    Filed: December 14, 2016
    Publication date: December 27, 2018
    Inventors: Gernot JÄEGER, Amgad Salah MOUSSA, Simon KLAFFL, Thomas HAMEDINGER, Wolf KLOECKNER, Swantje BEHNKEN
  • Publication number: 20180334694
    Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.
    Type: Application
    Filed: November 17, 2016
    Publication date: November 22, 2018
    Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Publication number: 20180008943
    Abstract: An orbital shaker with a balancing device that automatically and passively compensates, without supply of external energy, forces and moments which are caused by imbalance and arise during operation, in particular as a result of a possible variable loading (mass, geometry of the containers, properties of the contents) and variable operating parameters (speed of rotation and shaking radius). The balancing device can be designed such that only the unbalance forces (static balancing) and/or the unbalance moments (dynamic balancing) are compensated.
    Type: Application
    Filed: July 20, 2015
    Publication date: January 11, 2018
    Inventors: Burkhard CORVES, Mathias SCHUMACHER, Jochen BÜCHS, Wolf KLÖCKNER