Patents by Inventor Wolfgang Bruns

Wolfgang Bruns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Printing machine with hybrid printing technology
    Patent number: 11951733
    Abstract: The invention relates to a printing machine with hybrid printing technology for printing on a continuous material web.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 9, 2024
    Assignee: Windmöller & Hölscher KG
    Inventors: Sven Michael, Thomas Boosmann, Wolfgang Cordroch, Ralph Luxem, Jens Voelschow, Christian Bruns, Nico Schröder, Martin Flaspöhler, Nils-Henrik Schirmeisen
  • Variants of bovine pancreatic trypsin inhibitor produced by recombinant DNA technology, process expression vector and recombinant host therefor and pharmaceutical use thereof
    Patent number: 5770568
    Abstract: Peptides having essentially the sequence of bovine pancreatic trypsin inhibitor (aprotinin) wherein one or more of the amino acids at positions 15, 16, 17, 18, 34, 39 and 52 are replaced by any naturally occurring amino acid produced by recombinant DNA technology, process, expression vector and recominant host therefor and pharmaceutical use thereof. Such peptides being useful as therapeutic agents in diseases connected with the presence of excessive amounts of proteinases.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: June 23, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ernst-August Auerswald, Wolfgang Bruns, Dietrich Horlein, Gerd Reinhardt, Eugen Schnabel, Werner Schroder
  • Pancreatic secretory tryspin inhibitor and variants thereof produced by a recombinant host therefore and pharmaceutical use thereof
    Patent number: 5126322
    Abstract: The present invention relates to a peptide having essentially the amino acid sequence of pancreatic secretory trypsin inhibitor (PSTI). The present invention also relates to variants of such peptide wherein one or more of the amino acids in the original sequence are replaced by other amino acids. These peptides show an advantageously modified specificity in their inhibotory action. A method of preparation of the peptides and their pharmaceutical use is also described.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: June 30, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: John Collins, Helmut Blocker, Ronald Frank, Friedhelm Maywald, Hans Fritz, Wolfgang Bruns
  • Variants of bovine pancreatic trypsin inhibitor and pharmaceutical use thereof
    Patent number: 5118668
    Abstract: Peptides having essentially the sequence of bovine pancreatic trypsin inhibitor (aprotinin) wherein one or more of the amino acids at positions 15, 16, 17, 18, 34, 39 and 52 are replaced by any naturally occurring amino acid produced by recombinant DNA technology, process, expression vector and recominant host therefor and pharmaceutical use thereof. Such peptides being useful as therapeutic agents in diseases connected with the presence of excessive amounts of proteinases.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: June 2, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ernst-August Auerswald, Wolfgang Bruns, Dietrich Horlein, Gerd Reinhardt, Eugen Schnabel, Werner Schroder
  • Homologs of aprotinin produced from a recombinant host, process, expression vector and recombinant host therefor and pharmaceutical use thereof
    Patent number: 5032573
    Abstract: Microbially produced aprotinin and aprotinin homologs used for treating patients suffering from an excess release of pancreatic elastase, serum elastase or leukocyte elastase.
    Type: Grant
    Filed: October 2, 1989
    Date of Patent: July 16, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ernst-August Auerswald, Werner Schroder, Eugen Schnabel, Wolfgang Bruns, Gerd Reinhardt, Michael Kotick
  • Homologs of aprotinin produced from a recombinant host, process expression vector and recombinant host therefor and pharaceutical use thereof
    Patent number: 4894436
    Abstract: Microbially produced aprotinin and aprotinin homologs used for treating patients suffering from an excess release of pancreatic elastase, serum elastase or leukocyte elastase.
    Type: Grant
    Filed: March 23, 1987
    Date of Patent: January 16, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ernst-August Auerswald, Werner Schroder, Eugen Schnabel, Wolfgang Bruns, Gerd Reinhardt, Michael Kotick