Patents by Inventor Wolfgang Freudemann
Wolfgang Freudemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11833258Abstract: The present disclosure relates to a method of steam-sterilizing liquid-filled medical devices, e.g., filtration and/or diffusion devices like ultrafilters and capillary dialyzers.Type: GrantFiled: August 16, 2018Date of Patent: December 5, 2023Assignee: GAMBRO LUNDIA ABInventors: Ralf Flieg, Wolfgang Freudemann, Torsten Knoer
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Publication number: 20210187137Abstract: The present disclosure relates to a method of steam-sterilizing liquid-filled medical devices, e.g., filtration and/or diffusion devices like ultrafilters and capillary dialyzers.Type: ApplicationFiled: August 16, 2018Publication date: June 24, 2021Inventors: Ralf FLIEG, Wolfgang FREUDEMANN, Torsten KNOER
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Publication number: 20200353694Abstract: The present disclosure relates to a method of sealing ports of medical devices, e.g., filtration and/or diffusion devices like ultrafilters and capillary dialyzers.Type: ApplicationFiled: August 20, 2018Publication date: November 12, 2020Inventors: Claudia ASSMANN, Ralf FLIEG, Wolfgang FREUDEMANN, Torsten KNOER
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Publication number: 20200215493Abstract: The present disclosure relates to a process for testing the integrity of membranes in a filter module. Specifically, the process is applied to filters for extracorporeal blood treatment, in particular, filters comprising both filter membranes and particulate material.Type: ApplicationFiled: August 15, 2018Publication date: July 9, 2020Inventors: Claudia ASSMANN, Ralf FLIEG, Wolfgang FREUDEMANN, Torsten KNOER, Mehmet YILDIRIM
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Patent number: 10052427Abstract: A filter apparatus, a method for the manufacture of the filter apparatus, the use of the filter apparatus in medical, chemical and/or biotechnological applications, and an apparatus for use in the manufacture of the filter apparatus. The filter apparatus has a cylindrical housing and a plurality of hollow fibers. The hollow fibers are combined to form a bundle in the housing and are embedded and held in each case at the end sides in a molding compound. The filtrate space is filled with particles of a chemically or physically active substance.Type: GrantFiled: November 5, 2013Date of Patent: August 21, 2018Assignee: GAMBRO LUNDIA ABInventors: Ralf Flieg, Torsten Knoer, Wolfgang Freudemann, Mehmet Yildirim, Martin Rempfer, Steffen Wagner, Markus Storr
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Patent number: 9844621Abstract: A separation material includes a matrix that is bound to a saccharide, enabling the separation from a liquid of substances that selectively bind the saccharide. A method for preparing the separation material and a method for separating substances from a liquid that selectively bind a saccharide of the separation material are also described. A device employs the separation material for separating from a liquid substances that selectively bind to the saccharide of the separation material.Type: GrantFiled: August 7, 2012Date of Patent: December 19, 2017Assignee: GAMBRO LUNDIA ABInventors: Martin Rempfer, Wolfgang Freudemann, Cornelia Winz, Ralf Flieg, Markus Storr, Sandra Homeyer, Torsten Knoer
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Patent number: 9259710Abstract: A separation material includes a saccharide bound via a linker to a matrix for enabling the separation from a liquid of substances that selectively bind to saccharide moieties. A method for preparing the material, a method for separating from a liquid substances that selective bind to saccharides, and a device including the separation material are also disclosed.Type: GrantFiled: August 7, 2012Date of Patent: February 16, 2016Assignee: Gambro Lunia ABInventors: Martin Rempfer, Wolfgang Freudemann, Cornelia Winz, Ralf Flieg, Markus Storr, Manuela Klotz, Sandra Homeyer, Torsten Knoer
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Publication number: 20150320924Abstract: A filter apparatus, a method for the manufacture of the filter apparatus, the use of the filter apparatus in medical, chemical and/or biotechnological applications, and an apparatus for use in the manufacture of the filter apparatus. The filter apparatus has a cylindrical housing and a plurality of hollow fibers. The hollow fibers are combined to form a bundle in the housing and are embedded and held in each case at the end sides in a molding compound. The filtrate space is filled with particles of a chemically or physically active substance.Type: ApplicationFiled: November 5, 2013Publication date: November 12, 2015Inventors: Ralf Flieg, Torsten Knoer, Wolfgang Freudemann, Mehmet Yildirim, Martin Rempfer, Steffen Wagner, Markus Storr
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Publication number: 20150111194Abstract: A separation material includes a saccharide bound via a linker to a matrix for enabling the separation from a liquid of substances that selectively bind to saccharide moieties. A method for preparing the material, a method for separating from a liquid substances that selective bind to saccharides, and a device including the separation material are also disclosed.Type: ApplicationFiled: August 7, 2012Publication date: April 23, 2015Applicant: GAMBRO LUNDIA ABInventors: Martin Rempfer, Wolfgang Freudemann, Cornelia Winz, Ralf Flieg, Markus Storr, Manuela Klotz, Sandra Homeyer, Torsten Knoer
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Publication number: 20140166580Abstract: A separation material includes a matrix that is bound to a saccharide, enabling the separation from a liquid of substances that selectively bind the saccharide. A method for preparing the separation material and a method for separating substances from a liquid that selectively bind a saccharide of the separation material are also described. A device employs the separation material for separating from a liquid substances that selectively bind to the saccharide of the separation material.Type: ApplicationFiled: August 7, 2012Publication date: June 19, 2014Applicant: GAMBRO LUNDIA ABInventors: Martin Rempfer, Wolfgang Freudemann, Cornelia Winz, Ralf Flieg, Markus Storr, Sandra HOMEYER, Torsten KNOER
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Patent number: 8303819Abstract: A separating material formed by a solid substrate having a substrate surface, primary or secondary amines coupled to the substrate surface, and a graft polymer formed on the substrate by covalently coupling the primary or secondary amines with a thermally labile radical initiator and subsequently contacting the substrate surface with a solution of one or more polymerizable monomers. Methods for the extracorporeal treatment of blood, blood plasma or blood serum employing the separating material, for affinity adsorption, ion-exchange adsorption, hydrophobic adsorption, or hydrophilic adsorption employing the separating material, and a separating column employing the separating material are also disclosed.Type: GrantFiled: February 16, 2012Date of Patent: November 6, 2012Assignee: Gambro Lundia ABInventors: Markus Storr, Egbert Muller, Wolfgang Freudemann
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Publication number: 20120208256Abstract: An immobilized enzyme comprises a solid support, an enzyme linked to the solid support and a spacer for coupling the enzyme to the solid support. A method for the production of immobilized enzymes comprises: providing a solid support having amino-functional groups coupled to the support surface; covalently coupling the amino-functional groups with a thermally labile radical initiator; and, contacting the support surface with a solution of polymerizable monomers. The polymerizable monomers comprise functional groups which do not take part in radical polymerization, under conditions where thermally initiated graft copolymerization of the monomers takes place, to form polymer chains on the surface of the support. If the polymer chains do not already comprise primary amino-functional groups, the method further comprises transforming the functional groups in the polymer chains into groups comprising primary amino-functional groups.Type: ApplicationFiled: October 20, 2010Publication date: August 16, 2012Applicant: GAMBRO LUNDIA ABInventors: Ralf Flieg, Manuela Klotz, Markus Storr, Martin Rempfer, Wolfgang Freudemann, Cornelia Winz, Bernd Krause, Markus Hornung
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Publication number: 20120160771Abstract: A separating material formed by a solid substrate having a substrate surface, primary or secondary amines coupled to the substrate surface, and a graft polymer formed on the substrate by covalently coupling the primary or secondary amines with a thermally labile radical initiator and subsequently contacting the substrate surface with a solution of one or more polymerizable monomers. Methods for the extracorporeal treatment of blood, blood plasma or blood serum employing the separating material, for affinity adsorption, ion-exchange adsorption, hydrophobic adsorption, or hydrophilic adsorption employing the separating material, and a separating column employing the separating material are also disclosed.Type: ApplicationFiled: February 16, 2012Publication date: June 28, 2012Applicant: GAMBRO LUNDIA ABInventors: Markus Storr, Egbert Müller, Wolfgang Freudemann
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Patent number: 8142844Abstract: The present invention provides a separating material producable by a) providing a solid substrate, having amino-functional groups coupled to the substrate surface, b) covalently coupling of the amino-functional groups with a thermally labile radical initiator, c) contacting the substrate surface with a solution of polymerizable monomers under conditions, where thermally initiated graft copolymerization of the monomers takes place, to form a structure of adjacent functional polymer chains on the surface of the substrate.Type: GrantFiled: August 30, 2004Date of Patent: March 27, 2012Assignee: Gambro Lundia ABInventors: Markus Storr, Egbert Müller, Wolfgang Freudemann
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Publication number: 20060264355Abstract: The present invention provides a separating material producable by a) providing a solid substrate, having amino-functional groups coupled to the substrate surface, b) covalently coupling of the amino-functional groups with a thermally labile radical initiator, c) contacting the substrate surface with a solution of polymerizable monomers under conditions, where thermally initiated graft copolymerization of the monomers takes place, to form a structure of adjacent functional polymer chains on the surface of the substrate.Type: ApplicationFiled: August 30, 2004Publication date: November 23, 2006Inventors: Markus Storr, Egbert Muller, Wolfgang Freudemann