Patents by Inventor Wolfgang Guba

Wolfgang Guba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzooxazole, oxazolopyridine, benzothiazole and thiazolopyridine derivatives
    Publication number: 20070093521
    Abstract: This invention is concerned with compounds of the formula wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: August 31, 2006
    Publication date: April 26, 2007
    Inventors: Alfred Binggeli, Andreas Christ, Luke Granville Green, Wolfgang Guba, Hans-Peter Maerki, Rainer Martin, Peter Mohr
  • Amide derivatives as somatostatin receptor 5 antagonists
    Publication number: 20060276508
    Abstract: This invention is concerned with compounds of the formula wherein R1 to R5, R5? and A are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: May 26, 2006
    Publication date: December 7, 2006
    Inventors: Alfred Binggeli, Andreas Christ, Luke Green, Wolfgang Guba, Hans-Peter Maerki, Rainer Martin, Peter Mohr
  • Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives
    Publication number: 20060205718
    Abstract: This invention is concerned with compounds of the formula wherein A, B1, B2, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
    Type: Application
    Filed: March 2, 2006
    Publication date: September 14, 2006
    Inventors: Alfred Binggeli, Andreas Christ, Luke Green, Wolfgang Guba, Hans-Peter Maerki, Rainer Martin, Peter Mohr
  • New morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity
    Publication number: 20060178510
    Abstract: The present invention refers to chemical compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1. These compounds can be used for the preparation of medicaments.
    Type: Application
    Filed: January 13, 2006
    Publication date: August 10, 2006
    Inventors: Jonathan Bentley, Claire Dawson, Wolfgang Guba, Paul Hebeisen, Nathaniel Monck, Robert Pratt, Hans Richter, Stephan Roever, Vicki Ruston
  • Benzodioxole derivatives
    Publication number: 20050143373
    Abstract: The present invention relates to compounds of the general formula and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases such as obesity by selective modulation of CB1 receptors.
    Type: Application
    Filed: February 22, 2005
    Publication date: June 30, 2005
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Benzodioxole derivatives
    Patent number: 6900227
    Abstract: The present invention relates to compounds of the general formula and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases such as obesity by selective modulation of CB1 receptors.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: May 31, 2005
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Novel pyrrolyl-thiazole derivatives
    Publication number: 20040147572
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: December 22, 2003
    Publication date: July 29, 2004
    Inventors: Wolfgang Guba, Wolfgang Haap, Hans Peter Marty, Robert Narquizian
  • Benzodioxole derivatives
    Publication number: 20040142922
    Abstract: The present invention relates to compounds of the general formula 1
    Type: Application
    Filed: July 24, 2003
    Publication date: July 22, 2004
    Inventors: Alexander Alanine, Konrad Bleicher, Wolfgang Guba, Wolfgang Haap, Dagmar Kube, Thomas Luebbers, Jean-Marc Plancher, Olivier Roche, Mark Rogers-Evans, Gisbert Schneider, Jochen Zuegge
  • Aminothiazole derivatives
    Publication number: 20040038990
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: August 5, 2003
    Publication date: February 26, 2004
    Inventors: Wolfgang Guba, Patrizio Mattei, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger