Patents by Inventor Wolfgang H. Dillman

Wolfgang H. Dillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for in vivo regulation of cardiac muscle contractility
    Patent number: 7745416
    Abstract: A method for regulating in vivo calcium transport in cardiac muscle of animals suffering from congestive heart failure is disclosed. According to the method, calcium ATPase activity (which decreases as congestive heart failure develops) and cardiac muscle contractility augmented by delivering a gene which operatively encodes the enzyme into the heart. Delivery systems, including but not limited to using adeno-associated viral vectors are provided. Methods for monitoring the expression and effect of the gene product on cardiac performance are also provided.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: June 29, 2010
    Assignee: The Regents of the University of California
    Inventors: Wolfgang H. Dillman, Frank Giordano, Ruben Mestril