Patents by Inventor Wolfgang Hofgartner

Wolfgang Hofgartner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200246385
    Abstract: Provided herein are micro-organoids, referred to herein as Functional Physiological Units (FPUs), that are capable of replacing or augmenting one or more physiological functions in an individual, which are useful in the treatment of individuals lacking, or suffering a deficit in, said physiological function.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Applicant: Celularity Inc.
    Inventors: Robert J. HARIRI, Mohit BHATIA, Jia-Lun WANG, Wolfgang HOFGARTNER, Qian YE
  • Patent number: 10590381
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: March 17, 2020
    Assignee: Celularity, Inc.
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20190376027
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Applicant: Celularity, Inc.
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20180346877
    Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.
    Type: Application
    Filed: October 14, 2016
    Publication date: December 6, 2018
    Applicant: CELULARITY, INC.
    Inventors: Xiaokui ZHANG, Ivana DJURETIC, Lin KANG, Vanessa VOSKINARIAN-BERSE, Bhavani STOUT, Robert J. HARIRI, Wolfgang HOFGARTNER, James EDINGER, Eric LAW, Vladimir JANKOVIC
  • Publication number: 20180298328
    Abstract: Provided herein are stimulated placental stem cells and methods of treating individuals having diseases or disorders of the circulatory system using stimulated placental cells. The invention also provides methods of inducing angiogenesis using such stimulated cells or populations of cells comprising such stimulated cells.
    Type: Application
    Filed: May 25, 2016
    Publication date: October 18, 2018
    Applicant: Celularity, Inc.
    Inventors: Kathy E. KARASIEWICZ-MENDEZ, Aleksandar FRANCKI, Jeffrey TURNER, Eric LAW, Jennifer PAREDES, Kristen LABAZZO, Hemlata RANA, Wolfgang HOFGARTNER, Robert J. HARIRI
  • Publication number: 20170327788
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Application
    Filed: July 28, 2017
    Publication date: November 16, 2017
    Applicant: Anthrogenesis Corporation
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Patent number: 9725694
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: August 8, 2017
    Assignee: Anthrogenesis Corporation
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20170128625
    Abstract: Provided herein are organoids comprising decellularized placental vascular scaffold comprising, or consisting of, a decellularized placental vascular scaffold, and methods of making and using the same.
    Type: Application
    Filed: June 15, 2016
    Publication date: May 11, 2017
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Mohit B. Bhatia, Robert J. Hariri, Wolfgang Hofgartner, Jia-Lun Wang, Qian Ye
  • Patent number: 9598669
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: March 21, 2017
    Assignee: Anthrogenesis Corporation
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20160354408
    Abstract: Provided herein are micro-organoids, referred to herein as Functional Physiological Units (FPUs), that are capable of replacing or augmenting one or more physiological functions in an individual, which are useful in the treatment of individuals lacking, or suffering a deficit in, said physiological function.
    Type: Application
    Filed: February 10, 2015
    Publication date: December 8, 2016
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Robert J. HARIRI, Mohit BHATIA, Jia-Lun WANG, Wolfgang HOFGARTNER, Qian YE
  • Publication number: 20150313948
    Abstract: Provided herein are uses of compositions comprising extracellular matrix (ECM) and compositions comprising ECM components in the treatment of non-dental oral lesions.
    Type: Application
    Filed: December 6, 2013
    Publication date: November 5, 2015
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Robert J. Hariri, Jodi P. Gurney, Mohit B. Bhatia, Wolfgang Hofgartner
  • Publication number: 20150246072
    Abstract: Provided herein are methods for forming three-dimensional tissues in vivo. In one embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells. In another embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells and at least one composition that comprises an extracellular matrix (ECM). In another embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells, at least one composition that comprises an extracellular matrix (ECM), and at least one other additional components.
    Type: Application
    Filed: September 3, 2013
    Publication date: September 3, 2015
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Mohit B. Bhatia, Robert J. Hariri, Wolfgang Hofgartner, Jia-Lun Wang, Qian Ye
  • Publication number: 20150224226
    Abstract: Provided herein are methods of generating tissues and organs in vitro or ex vivo comprising depositing cells and extracellular matrix onto a surface, as well as methods of using such tissues and organs. In one embodiment, the cells and ECM used in accordance with the methods for generating tissues (e.g., three-dimensional tissues) and organs described herein are deposited as part of the same composition. In another embodiment, the cells and ECM used in accordance with the methods for generating tissues (e.g., three-dimensional tissues) and organs described herein are deposited as part of different compositions.
    Type: Application
    Filed: September 3, 2013
    Publication date: August 13, 2015
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Mohit B. Bhatia, Robert J. Hariri, Wolfgang Hofgartner, Jia-Lun Wang, Qian Ye
  • Publication number: 20150017140
    Abstract: Provided herein are organoids comprising decellularized placental vascular scaffold comprising, or consisting of, a decellularized placental vascular scaffold, and methods of making and using the same.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 15, 2015
    Applicant: Anthrogenesis Corporation
    Inventors: Mohit B. Bhatia, Robert J. Hariri, Wolfgang Hofgartner, Jia-Lun Wang, Qian Ye
  • Publication number: 20100291679
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Application
    Filed: July 29, 2010
    Publication date: November 18, 2010
    Inventors: James W. Edinger, Mohammad Heidaran, Wolfgang Hofgartner
  • Publication number: 20070190042
    Abstract: The present invention provides improved compositions and methods for the collection of stem cells from an organ, e.g., placenta. The invention provides a stem cell collection composition comprising an apoptosis inhibitor and, optionally, an enzyme such as a protease or mucolytic enzyme, vasodilator, necrosis inhibitor, oxygen-carrying perfluorocarbon, or an organ preserving compound. The invention provides methods of using the stem cell collection composition to collect stem cells and to preserve populations of stem cells.
    Type: Application
    Filed: December 28, 2006
    Publication date: August 16, 2007
    Inventors: James Edinger, Mohamad Heidaran, Wolfgang Hofgartner