Patents by Inventor Wolfgang Hofmann

Wolfgang Hofmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10683894
    Abstract: An air bearing for movably bearing at least two elements includes a bearing main body with a first air outflow channel and a second air outflow channel. The first air outflow channel is supplied with air via at least one first air delivery device. The second air outflow channel is supplied with air via at least one second air delivery device. A sensor detects at least one of a bearing stroke, a bearing pressure, and a bearing throughflow, and a controller adjusts the supply of the air to at least one of the first air outflow channel and the second air outflow channel in accordance with the at least one of the bearing stroke, the bearing pressure, and the bearing throughflow.
    Type: Grant
    Filed: March 25, 2018
    Date of Patent: June 16, 2020
    Assignee: Carl Zeiss Industrielle Messtechnik GmbH
    Inventors: Malte Langmack, Steffen Strauss, Wolfgang Strauss, Raphael Koch, Christof Poglitsch, Holger Hofmann, Nikolai Zeller
  • Publication number: 20200132667
    Abstract: It is provided a measuring cartridge (1) for measuring at least one constituent of a liquid sample, in particular blood, and for performing quality control, the cartridge comprising: a casing (3) insertable into a reception opening (51) of a measuring instrument (50), the casing (3) at least partly surrounding an inner space (5); wherein the inner space contains: a measurement cell (7) comprising a reception space (9) for the sample and at least one sensor area (11) with which the sample is in contact when loaded into the reception space (9); plural quality control containers (13a,13b,13c) for respectively holding different quality control solutions (15a,15b,15c); a solution routing system (17) adapted to selectively route one of the quality control solutions (15a,15b,15c) from the respective quality control container (13a,13b,13c) into the reception space (9) of the measurement cell (7).
    Type: Application
    Filed: October 28, 2019
    Publication date: April 30, 2020
    Inventors: Wolfgang HOFMANN, Wolf-Dietrich STEINBÖCK, Josef HINDINGER
  • Publication number: 20190339225
    Abstract: The invention relates to a system for determining and/or monitoring a state variable of a measurement object comprising an analysis sensor, a control apparatus and a read-out apparatus. The analysis sensor is configured to be introducible into the measurement object for remaining within the same, to be sensitive to an ion type and to generate measurement data based on a concentration of the ion type in the measurement object. The control apparatus controls the analysis sensor with respect to the generation of the measurement data. The read-out apparatus reads the measurement data out of the analysis sensor. Further, the invention relates to a respective method.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 7, 2019
    Inventors: Michael Jank, Susanne Oertel, Alicia Marion Zoerner, Wolfgang Thieme, Thomas Heckel, Christopher Joffe, Esther Ann Renner, Christian Hofmann, Nadine Ramona Lang, Matthias Struck, Achim Endruschat, Holger Gerstner
  • Patent number: 10315975
    Abstract: The present invention relates to a method for the regioselective hydroformylation of polyunsaturated acyclic hydrocarbons, which are 1, 3 butadienes, which, in the 2 position, bear a saturated or monounsaturated or polyunsaturated acyclic hydrocarbon radical. The present invention also relates to the production of secondary products of these hydroformylation products, especially of ambrox.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: June 11, 2019
    Assignees: BASF SE, Ruprecht-Karls-Universität Heidelberg
    Inventors: Julia Strautmann, Stefan Rüdenauer, Christian Rein, Melanie Weingarten, Rocco Paciello, Wolfgang Siegel, Michael Breuer, Peter Hofmann, Sebastian Schmidt
  • Patent number: 10023025
    Abstract: A heat management system for an internal combustion engine has an engine cooling circuit, a main cooling circuit that has a main cooler, a heating circuit that has a heating heat exchanger, a coolant pump that moves coolant through the circuits and a rotary slide valve that has at least one switched and at least one non-switched inlet, such that the heating return flow leads into a switchable inlet of the rotary slide valve.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: July 17, 2018
    Assignee: Bayerische Motoren Werke Aktiengesellschaft
    Inventors: Rainer Richter, Wolfgang Hofmann, Wolfram Enke
  • Patent number: 9623440
    Abstract: A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: April 18, 2017
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Wolfgang Hofmann, Taghi Noormofidi, Doris Zahrl
  • Publication number: 20170030252
    Abstract: To ventilate a heat management system of an internal combustion engine, in which coolants circulate in several coolant circuits, connected inlets of a rotary valve may be opened and closed in a predetermined sequence, in order to ventilate one or more of the coolant circuits in the direction of the compensation tank, by means of at least one ventilation circuit which is in fluid connection with a coolant compensation tank. The rotary valve may be controlled by means of a control unit, wherein a non-connected inlet of the rotary valve is in fluid connection with the coolant compensation tank.
    Type: Application
    Filed: July 22, 2016
    Publication date: February 2, 2017
    Inventors: Rainer RICHTER, Wolfgang HOFMANN, Wolfram ENKE
  • Patent number: 9539387
    Abstract: The invention relates to an insert and a vial for the infusion of a liquid. The vial comprises a hollow body, a grasp portion and a head. The head comprises a delivery opening defining an axis X; a septum for closing the opening; and at least one circumferential push surface next to the head and firmly connected to the grasp portion. The insert is suitable to deliver the liquid and to receive the vial along axis X. The insert comprises a main body with lower ducts, an inner part and a piercing spike. The inner part defines a seat for the vial head, and comprises one slit for engaging the circumferential push surface. The spike is suitable to pierce the vial septum and defines upper ducts. The inner part is able to rotate inside the main body between a fluidly open configuration and a fluidly closed configuration.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: January 10, 2017
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHALND GMBH
    Inventors: Massimo Fini, Alain Veneroni, Wolfgang Wehmeyer, Wolfgang Hofmann
  • Publication number: 20160325601
    Abstract: A heat management system for an internal combustion engine has an engine cooling circuit, a main cooling circuit that has a main cooler, a heating circuit that has a heating heat exchanger, a coolant pump that moves coolant through the circuits and a rotary slide valve that has at least one switched and at least one non-switched inlet, such that the heating return flow leads into a switchable inlet of the rotary slide valve.
    Type: Application
    Filed: July 22, 2016
    Publication date: November 10, 2016
    Inventors: Rainer RICHTER, Wolfgang HOFMANN, Wolfram ENKE
  • Publication number: 20160220604
    Abstract: The present invention relates to magnesium-liposome complexes with a delayed release of magnesium, coated at least partially with a polyalkylene glycol compound. In addition, the present invention relates to methods for synthesis of the magnesium-liposome complexes as well as use thereof in the treatment of diseases associated with a magnesium deficiency.
    Type: Application
    Filed: September 16, 2014
    Publication date: August 4, 2016
    Applicant: Fresenius Medical Care Deutschland GmbH
    Inventors: Janine BUECHEL, Wolfgang HOFMANN, Kristina GUNDLACH, Jasmin YILLAH, Sonja STEPPAN, Hans-Juergen ARENS
  • Patent number: 9194852
    Abstract: A method and an apparatus for accelerating the equilibration of a fluid, typically the reference fluid of an analyzer, are provided, the surface of the fluid being in contact with a gas phase. The device can include a cassette, which can be exchangeably inserted into an analyzer and which holds at least one flexible, gas-tight bag, in which the fluid and the gas phase are accommodated. The cassette or the analyzer can include at least one transmitting element, which can be caused to vibrate and which mechanically contacts the flexible bag in order to input mechanical energy into the liquid in at least one wall region.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: November 24, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christoph Pfeiffer, Wolfgang Hofmann, Horst Ruether
  • Patent number: 9075033
    Abstract: A reagent cartridge which can be exchangeably inserted into an analyzer and having a plurality of reagent bags furnished with connecting lines, each of which may optionally be connected to an input device of the analyzer, and method for operating the analyzer are disclosed. Each reagent bag has an analyzer-controlled multi-way valve with at least two valve positions at the point where the respective connecting line departs, such that the first valve position opens a fluid path between the connecting line and the reagent bag, while the second valve position closes off the reagent bag and opens a fluid path between a ventilation source, e.g. ambient air, and the connecting line. The connecting lines of the reagent bags departing from the multi-way valve open directly into a common rail or a collector valve.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: July 7, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Wolf-Dietrich Steinboeck, Wolfgang Hofmann
  • Publication number: 20150079685
    Abstract: A method and an apparatus for accelerating the equilibration of a fluid, typically the reference fluid of an analyzer, are provided, the surface of the fluid being in contact with a gas phase. The device can comprise a cassette, which can be exchangeably inserted into an analyzer and which holds at least one flexible, gas-tight bag, in which the fluid and the gas phase are accommodated. The cassette or the analyzer can include at least one transmitting element, which can be caused to vibrate and which mechanically contacts the flexible bag in order to input mechanical energy into the liquid in at least one wall region.
    Type: Application
    Filed: November 24, 2014
    Publication date: March 19, 2015
    Inventors: Christoph Pfeiffer, Wolfgang Hofmann, Horst Ruether
  • Patent number: 8915875
    Abstract: The invention relates to a device and a method for depletion of hepcidin from blood for treatment of iron deficiency, in particular in anemic patients suffering from chronic renal failure, with the goal of increasing the availability of iron in the body and thus improving the treatment of the anemia. The hepcidin adsorbent comprises a matrix and a hepcidin-binding ligand covalently bonded to the matrix with an affinity having a dissociation constant KD of less than 200 nM.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: December 23, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Jutta Passlick-Deetjen, Wolfgang Hofmann
  • Publication number: 20130255834
    Abstract: The invention relates to an insert and a vial for the infusion of a liquid. The vial comprises a hollow body, a grasp portion and a head. The head comprises a delivery opening defining an axis X; a septum for closing the opening; and at least one circumferential push surface next to the head and firmly connected to the grasp portion. The insert is suitable to deliver the liquid and to receive the vial along axis X. The insert comprises a main body with lower ducts, an inner part and a piercing spike. The inner part defines a seat for the vial head, and comprises one slit for engaging the circumferential push surface. The spike is suitable to pierce the vial septum and defines upper ducts. The inner part is able to rotate inside the main body between a fluidly open configuration and a fluidly closed configuration.
    Type: Application
    Filed: December 1, 2011
    Publication date: October 3, 2013
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Massimo Fini, Alain Veneroni, Wolfgang Wehmeyer, Wolfgang Hofmann
  • Publication number: 20120063954
    Abstract: The invention relates to a device and a method for depletion of hepcidin from blood for treatment of iron deficiency, in particular in anemic patients suffering from chronic renal failure, with the goal of increasing the availability of iron in the body and thus improving the treatment of the anemia. The hepcidin adsorbent comprises a matrix and a hepcidin-binding ligand covalently bonded to the matrix with an affinity having a dissociation constant KD of less than 200 nM.
    Type: Application
    Filed: July 15, 2010
    Publication date: March 15, 2012
    Inventors: Jutta Passlick-Deetjen, Wolfgang Hofmann
  • Publication number: 20090176314
    Abstract: A reagent cartridge which can be exchangeably inserted into an analyzer and having a plurality of reagent bags furnished with connecting lines, each of which may optionally be connected to an input device of the analyzer, and method for operating the analyzer are disclosed. Each reagent bag has an analyzer-controlled multi-way valve with at least two valve positions at the point where the respective connecting line departs, such that the first valve position opens a fluid path between the connecting line and the reagent bag, while the second valve position closes off the reagent bag and opens a fluid path between a ventilation source, e.g. ambient air, and the connecting line. The connecting lines of the reagent bags departing from the multi-way valve open directly into a common rail or a collector valve.
    Type: Application
    Filed: January 7, 2009
    Publication date: July 9, 2009
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Wolf-Dietrich Steinboeck, Wolfgang Hofmann
  • Publication number: 20080249381
    Abstract: A combined apparatus for measuring the blood glucose level from an ocular fluid comprises a hand-held fluorescence photometer (D1) for determining the glucose level of the ocular fluid and a device (D2) for the amperometric or photometric determination of the blood glucose level. The fluorescence photometer (D1) comprises: first irradiating means (7,8,10) for providing a pilot beam (1) for irradiation of the eye (3) in order to excite a first fluorescence comprising a first wavelength band; first detecting means (8,9,12,13) for measuring the intensity of the of the pupil fluorescence within the first wavelength band; second irradiating means (17,18,21) for providing a measurement beam (5) for irradiation of the eye in order to excite an ocular sensor (4) to emit a second fluorescence comprising a second wavelength band; second detecting means (18,19,20,22,23,24,25) for measuring the intensity of the second fluorescence within the second wavelength band.
    Type: Application
    Filed: June 13, 2005
    Publication date: October 9, 2008
    Inventors: Achim Muller, Peter Herbrechtsmeier, Bernhard Seiferling, Wolfgang Hofmann
  • Patent number: 6808923
    Abstract: The invention is directed to a lentiviral vector system that can be used for episomal replication of a desired gene. The vector system contains a first vector containing a lentiviral gag gene encoding a lentiviral gag protein, a second vector containing an env gene encoding a functional envelope protein, and a lentiviral pol gene encoding a lentiviral pol protein. The pol protein is at least integrase, but that the integrase has been modified so that it is not capable of integration. This pol gene can be on the first or second vectors or on a third vector. The lentiviral gag and pol and the envelope protein are not on a single vector, and these vectors do not contain nucleotides to effectively package lentiviral RNA. The system also contains another vector having a nucleic acid sequence encoding a target molecule operably linked to a component of an episomal replicon and a lentiviral packaging sequence.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: October 26, 2004
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Alan Engelman, Wolfgang Hofmann, Joseph G. Sodroski, Richard Lu
  • Publication number: 20030013196
    Abstract: The invention is directed to a lentiviral vector system that can be used for episomal replication of a desired gene. The vector system contains a first vector containing a lentiviral gag gene encoding a lentiviral gag protein, a second vector containing an env gene encoding a functional envelope protein, and a lentiviral pol gene encoding a lentiviral pol protein. The pol protein is at least integrase, but that the integrase has been modified so that it is not capable of integration. This pol gene can be on the first or second vectors or on a third vector. The lentiviral gag and pol and the envelope protein are not on a single vector, and these vectors do not contain nucleotides to effectively package lentiviral RNA. The system also contains another vector having a nucleic acid sequence encoding a target molecule operably linked to a component of an episomal replicon and a lentiviral packaging sequence.
    Type: Application
    Filed: November 21, 2001
    Publication date: January 16, 2003
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Alan Engelman, Wolfgang Hofmann, Joseph Sodroski, Richard Lu