Patents by Inventor Wolfgang Karl

Wolfgang Karl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6767906
    Abstract: This application discloses 2-amino-6-anilino-purine derivatives of the formula I in which q is 1-5, and R1 is &agr;) —S(═O)k—NR6R7, in which  k is 1 or 2,  wherein under the proviso that R6 and R7 cannot be simultaneously hydrogen &agr;1) R6, R7 can be identical or different from one another and represent an aliphatic, carbocyclic, heterocyclic, carbocyclic-aliphatic or heterocyclic-aliphatic radical; hydrogen or lower aliphatic acyl; or &agr;2) R6 and R7 together are an alkylene or alkenylene radical having from 3 up to and including 9 C atoms, in which 1-3 C atoms can be replaced by oxygen, sulfur or nitrogen, &bgr;) N-(aryl lower alkyl)carbamoyl, or &ggr;) a radical of the formula —NH—S(═O)i—R8, in which  i is 1 or 2,  R8 is an aliphatic, carbocyclic or heterocyclic radical; or &dgr;) a radical of the formula —NH—C(═O)—R9,  and the other variable substituents are as defined herein.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: July 27, 2004
    Assignee: Novartis AG
    Inventors: Patricia Imbach, Hans-Georg Capraro, Jürg Zimmermann, Giorgio Caravatti, Pascal Furet, Wolfgang Karl-Diether Brill
  • Publication number: 20020016329
    Abstract: 2-Amino-6-anilino-purine derivatives of the formula I 1
    Type: Application
    Filed: August 10, 2001
    Publication date: February 7, 2002
    Inventors: Patricia Imbach, Hans-Georg Capraro, Jurg Zimmermann, Giorgio Caravatti, Pascal Furet, Wolfgang Karl-Diether Brill
  • Patent number: 6140332
    Abstract: Described are 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula I ##STR1## wherein the symbols are as defined in claim 1. Those compounds inhibit tyrosine protein kinase and can be used in the treatment of hyperproliferative diseases, for example tumour diseases.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: October 31, 2000
    Assignee: Novartis AG
    Inventors: Peter Traxler, Guido Bold, Wolfgang Karl-Diether Brill, Jorg Frei
  • Patent number: 6046045
    Abstract: The present invention relates to two processes for the treatment of antimicrobially, in particular antibacterially, acting quinolone- and naphthyridonecarboxylic acids and derivatives thereof with wood rot fungi, if appropriate in the presence of water and/or inert solid or liquid substrates and further auxiliaries.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: April 4, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinz-Georg Wetzstein, Hans-Georg Rast, Wolfgang Karl, Rainer Martens, Frantisek Zadrazil
  • Patent number: 5849749
    Abstract: The 6-(hydroxymethyl-ethyl)pyridines are prepared by a process in which the 3-hydroxymethylpyridines which are hydroxyl-protected in the 6-position are oxidized to the 3-aldehyde, this is then converted into the corresponding oxoheptenoic acid derivative using a Wittig-Homer reaction, after this the oxo group is reduced to the hydroxyl group and then the isomers are separated by chromatography. The 6-(hydroxymethyl-ethyl)pyridines are suitable as active compounds in medicaments, in particular in medicaments having antiarteriosclerotic activity.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: December 15, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter Fey, Rolf Angerbauer, Delf Schmidt, Hilmar Bischoff, Wolfgang Kanhai, Martin Radtke, Wolfgang Karl
  • Patent number: 3980499
    Abstract: Lithium haloboracites of the formula Li.sub.4 B.sub.7 O.sub.12 X where X is Cl, Br, I or a mixture thereof are useful as solid electrolytes for galvanic cells. Preferred lithium haloboracites are those in which X is a mixture of Br and Cl where Br is 20 to 50 mole percent of X.
    Type: Grant
    Filed: June 25, 1975
    Date of Patent: September 14, 1976
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Tom Allen Bither, Jr., Wolfgang Karl Jeitschko