Abstract: The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and\or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content.

Abstract: A valve system having a vacuum valve with a valve seat having a valve opening defining an opening axis and a first sealing surface around the valve opening, a valve closure having a second sealing surface and a drive unit coupled to the valve closure. A control and regulating unit preforming a pre-regulating step and a regulating step for the valve closure in a regulating cycle, the pre-regulating step moves the valve closure to a defined position and the regulating step the closure position is varied based on a determined control variable and a target value. The regulating and control unit updates at least during a part of the regulating cycle and a regulating profile is derived, the regulating profile is compared with a reference regulating profile and a regulating deviation is derived, an adapted pre-regulating position is provided as the actual pre-regulating position for the regulating cycle.

Abstract: A valve system having a vacuum valve with a valve seat having a valve opening defining an opening axis and a first sealing surface around the valve opening, a valve closure having a second sealing surface and a drive unit coupled to the valve closure. A control and regulating unit preforming a pre-regulating step and a regulating step for the valve closure in a regulating cycle, the pre-regulating step moves the valve closure to a defined position and the regulating step the closure position is varied based on a determined control variable and a target value. The regulating and control unit updates at least during a part of the regulating cycle and a regulating profile is derived, the regulating profile is compared with a reference regulating profile and a regulating deviation is derived, an adapted pre-regulating position is provided as the actual pre-regulating position for the regulating cycle.

Abstract: A tool holder, in particular for a measuring sensor, with an interface to a spindle of a machine tool is proposed. The tool holder comprises, as seen from the interface for the spindle, a material portion which differs from the customary basic material of a tool holder in a lower coefficient of linear expansion ? and/or in a lower heat conductivity ?. According to the invention, the material portion affords thermal decoupling between the tool-side portion of the tool holder and a tool received therein from the tool spindle for reducing a length change on account of an introduction of heat coming from a comparatively hot tool spindle.

Abstract: A tool holder, in particular for a measuring sensor, with an interface to a spindle of a machine tool is proposed. The tool holder comprises, as seen from the interface for the spindle, a material portion which differs from the customary basic material of a tool holder in a lower coefficient of linear expansion ? and/or in a lower heat conductivity ?. According to the invention, the material portion affords thermal decoupling between the tool-side portion of the tool holder and a tool received therein from the tool spindle for reducing a length change on account of an introduction of heat coming from a comparatively hot tool spindle.

Abstract: A method is proposed for measuring tools on a machine tool with a measuring device, wherein by means of a movement of a spindle of the machine tool the measuring device is temporarily positioned at a measuring point on the machine tool in order to carry out one or more measurements, the measuring point differing from a spindle mount. Furthermore, a measuring apparatus is proposed which is embodied in such a way that the measuring device can be positioned at a measuring point on the machine tool for a measuring operation by means of a spindle movement of a machine tool, said measuring point differing from a spindle mount.

Abstract: A method for measuring workpieces with a measuring probe on a machine tool with linear axes of motion and at least one pivoting axis is provided, whereby the deviation of an actual position of a calibrating body in a pivoted position, in relation to a theoretical pivoted position which the calibrating body ideally occupy without a pivoting error, is used to determine a correction value. An actual measured value for calculating a coordinate of a measuring point on a measurement object or a theoretical measuring-point coordinate to be approached on the measurement object is corrected using the correction value when a measurement is carried out on the measurement object in a corresponding pivoted position. A device for implementing the method is also provided.

Abstract: A method is proposed for measuring tools on a machine tool with a measuring device, wherein by means of a movement of a spindle of the machine tool the measuring device is temporarily positioned at a measuring point on the machine tool in order to carry out one or more measurements, the measuring point differing from a spindle mount. Furthermore, a measuring apparatus is proposed which is embodied in such a way that the measuring device can be positioned at a measuring point on the machine tool for a measuring operation by means of a spindle movement of a machine tool, said measuring point differing from a spindle mount.

Abstract: A touch probe is provided, including a deflectable stylus with a rest position mechanism on which the stylus is arranged, and a housing in which the rest position mechanism is accommodated. The rest position mechanism comprises a stylus holder with carrying elements and seating elements corresponding to the carrying elements that interact with the carrying elements to arrange the stylus holder in the touch probe. The carrying elements and seating elements form a sensing circuit which is closed when the carrying elements are in contact with the seating elements and which is open when one of the carrying elements is not in contact with a corresponding seating element. The rest position mechanism includes a spring element, which urges the stylus holder against the seating elements to position the stylus holder. Setting means, which allow setting of the pressing force of the spring element, are provided in the stylus holder.

Abstract: A receiving station (7) is proposed, having a receiving unit which is designed for radio reception of data from a measurement sensor (1), with two or more channels at different frequencies being available for selection for data transmission, which can receive data continuously from the measurement sensor on a current channel when in standby. According to the invention, a control unit (1) is provided, which scans the frequencies of the channels and blocks those channels for further selection in which a predefined interference level is exceeded. A measurement sensor as well as a measurement system having a receiving station and having a measurement sensor are also proposed.

Abstract: A touch probe is provided, including a deflectable stylus with a rest position mechanism on which the stylus is arranged, and a housing in which the rest position mechanism is accommodated. The rest position mechanism includes a stylus holder with carrying elements and seating elements corresponding to the carrying elements that interact with the carrying elements to arrange the stylus holder in the touch probe. The carrying elements and seating elements form a sensing circuit which is closed when the carrying elements are in contact with the seating elements and which is open when one of the carrying elements is not in contact with a corresponding seating element. The carrying elements are provided with electrical contacting means that is formed independently of a clamping device.

Abstract: A method for measuring workpieces with a measuring probe on a machine tool with linear axes of motion and at least one pivoting axis is provided, whereby the deviation of an actual position of a calibrating body in a pivoted position, in relation to a theoretical pivoted position which the calibrating body ideally occupy without a pivoting error, is used to determine a correction value. An actual measured value for calculating a coordinate of a measuring point on a measurement object or a theoretical measuring-point coordinate to be approached on the measurement object is corrected using the correction value when a measurement is carried out on the measurement object in a corresponding pivoted position. A device for implementing the method is also provided.

Abstract: A touch probe is provided, including a deflectable stylus with a rest position mechanism on which the stylus is arranged, and a housing in which the rest position mechanism is accommodated. The rest position mechanism comprises a stylus holder with carrying elements and seating elements corresponding to the carrying elements that interact with the carrying elements to arrange the stylus holder in the touch probe. The carrying elements and seating elements form a sensing circuit which is closed when the carrying elements are in contact with the seating elements and which is open when one of the carrying elements is not in contact with a corresponding seating element. The carrying elements are provided with electrical contacting means that is formed independently of a clamping device.

Abstract: A touch probe is provided, including a deflectable stylus with a rest position mechanism on which the stylus is arranged, and a housing in which the rest position mechanism is accommodated. The rest position mechanism comprises a stylus holder with carrying elements and seating elements corresponding to the carrying elements that interact with the carrying elements to arrange the stylus holder in the touch probe. The carrying elements and seating elements form a sensing circuit which is closed when the carrying elements are in contact with the seating elements and which is open when one of the carrying elements is not in contact with a corresponding seating element. The rest position mechanism includes a spring element, which urges the stylus holder against the seating elements to position the stylus holder. Setting means, which allow setting of the pressing force of the spring element, are provided in the stylus holder.

Abstract: A receiving station (7) is proposed, having a receiving unit which is designed for radio reception of data from a measurement sensor (1), with two or more channels at different frequencies being available for selection for data transmission, which can receive data continuously from the measurement sensor on a current channel when in standby. According to the invention, a control unit (1) is provided, which scans the frequencies of the channels and blocks those channels for further selection in which a predefined interference level is exceeded. A measurement sensor as well as a measurement system having a receiving station and having a measurement sensor are also proposed.

Abstract: Probe for attaching at certain times to the tool spindle of a machine tool, which probe emits by means of a stylus (5) a measuring signal which is transmitted via a transmission channel (8) to a receiving and evaluating device (9) of the machine tool. For power-saving purposes, the transmission channel (8) is kept in the functioning state, by means of an activation system contained in the probe, only during the actual measuring operation. The activation system comprises a switching device (15) and an electronic assembly (13), which is characterized in that, from when it reaches its switching position, a control check is carried out with respect to continuance of the switching position and the activation or deactivation of the transmission channel (8) is only triggered when the switching position continues uninterruptedly for the duration of a certain interrogation time.

Abstract: A laser light barrier system for measuring or checking tools or workpieces on machine tools has a support which can be fastened to the machine frame. The support has an elongate base housing and two block housings, which at a mutual longitudinal distance project transversely from the elongate base housing and one of which contains a transmitter and one a receiver. The laser beam extends at a distance from and approximately parallel to the elongate base housing. An elongate stop element which is held in position by means of a latching arrangement, extends, in the space between the laser beam and the base housing, in the longitudinal direction from one block housing to the other block housing, and wherein the elongate stop element snaps off in the event of a collision with a moving tool or workpiece and, as a result, actuates an electric switch which, by acting on the emergency stop device of the machine stops the latter.

Abstract: An electrical switch has a geometrically reproducibly precise switching point.

Abstract: Mechanical energy is supplied to an implement on a rotating spindle, and a generator on the implement converts the mechanical energy into electric power. Preferably the energy is supplied in the form of rotary motion via the work spindle. Alternatively, a fluent medium, for example, coolant or compressed air, can be supplied, in which case the medium is used to drive a turbine wheel coupled to the generator.

Abstract: A sensing head for a three-dimensional sensing of a workpiece includes a housing; a lid secured to the housing at one end thereof; a transmission member axially slidably received in the housing; a transducer mounted in the housing and cooperating with the transmission member for generating a signal representing axial displacements of the transmission member; a spring disposed in the housing and urging the transmission member toward the lid; and a bearing body disposed in the housing between the lid and the transmission member. The bearing body is a spherical segment having a base and a spherical surface. The base is in contact with an inner face of the lid. A sensing pin secured to the bearing body passes through the lid. The transmission member has a circular edge constituting a seat being in a circular contact with the spherical surface and centering the bearing body in the housing.