Abstract: The invention relates to conjugates comprising a D-enantiomer of a folic acid antagonist and a carrier. Furthermore, the invention relates to the production of such conjugates as well as their use.

Abstract: This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.

Abstract: A cyanoacrylate adhesive contains an added ester, the ester used being at least one partial and/or full ester of monobasic or polybasic aliphatic carboxylic acids containing 1 to 5 carbon atoms directly attached to one another and monohydric to pentahydric aliphatic alcohols containing 1 to 5 carbon atoms directly attached to one another, the number of carbon atoms directly attached to one another in the other aliphatic groups being at most three where one aliphatic group contains 4 or 5 carbon atoms.

Abstract: Adhesive sticks are obtained using water-based preparations of synthetic polymers of adhesive character and soaps which act as shaping gel-forming components. Mixtures of polyurethanes and polyvinyl pyrrolidone are used as the synthetic polymers. The polyurethane may be in the form of a dispersion and produced by reacting at least one polyol, at least one polyfunctional isocyanate and a component capable of salt formation in alkaline aqueous solution and/or a nonionic hydrophilic modifying agent.

Abstract: The present invention relates to a conjugate comprising an active substance and a compound having a binding site for metallic compounds. In addition, this invention relates to a process for the preparation of such a conjugate and its use.

Abstract: The present invention relates to conjugates, comprising an active substance, a polypeptide and a polyether, a process for the production of such conjugates as well as their use.

Abstract: An adhesive paste, free of water, based on a reaction product of a polyisocyanate component and a co-reactant selected from the group consisting of a polyol, a monofunctional fatty derivative component and mixtures thereof, wherein the reaction product contains moisture reactive isocyanate groups.

Abstract: The invention relates to a device for detecting input radiation such as X-rays, &ggr;-rays, ionizing radiation or fluorescent and low-level light. The device has at least one detection element comprising a sensor component (scintillator) for converting the input radiation into photons (scintillation light) in the UV, visible or IR part of the electromagnetic spectrum and an optical amplifier component which receives the light converted by the sensor component, forwards it for further processing and amplifies it at the same time. According to the invention, the amplifier component comprises at least one optical waveguide (1, 2, 2a, 2b, 20) whose material is optically pumped to amplify the scintillation light (3, 24, 25).

Abstract: The present invention relates to conjugates comprising a compound capable of emitting fluorescence, a linker and a protein. The present invention also concerns the preparation of such conjugates as well as their use.

Abstract: This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguishes itself in that an intracellularly cleavable linker is present between the active substance and the protein.

Abstract: A contour collimator has a plurality of plate-shaped diaphragm elements movably arranged with respect to each other in a guiding block to form a contour diaphragm for a radiation beam emitted by a radiation source towards the collimator, and at least one drive for moving the diaphragm elements. A drive is associated with each diaphragm element with the drives of a group of diaphragm elements being substantially adjacent, and a driving transmission arranged between each drive and the associated diaphragm element.

Abstract: The present invention relates to a process for preparing acid amides by reacting an acid with an aliphatic amine in molten urea. This invention also concerns a process for metalating compounds which can be bonded to a metal ion by reacting the compound with a metal ion in molten urea. Furthermore, the invention deals with the thus obtained products and their use for the therapy and/or diagnosis of tumors or inflammatory diseases.

Abstract: This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.

Abstract: This invention relates to a process for the preparation of polyether-including chlorins and/or bacteriochlorins, comprising the following steps:(a) bonding a polyether to a porphyrin and(b) reacting the polyether-including porphyrin with a reducing agent.Furthermore, this invention concerns the polyether-including chlorins and bacteriochlorins, obtained by the process, as well as the use thereof for the photodynamic treatment of tumors.

Abstract: A telecommunication device (1) is provided for identification of a caller number of a calling party. The telecommunication device (1) includes a caller identification circuit (5), a memory (10) for storing numbers of callers and a comparator (15) for comparing numbers of calling parties with the caller numbers stored in the memory. The telecommunication device supplies data of the calling party to a display device when the caller number of a calling party agrees with a caller number stored in memory. A truncation of the caller number of the calling party at its end by a predetermined number of digits occurs when there is no agreement between the caller number of the calling party and any of the numbers stored in the memory and a comparison of the branch exchange main numbers stored in the memory with the shortened caller number occurs.

Abstract: Method for controlling the speed of horizontally rotatable supply turntables for tape material. In such a method for controlling the speed by measurement on a moving tape, especially on a film tape (3) in cinema show operation by removal from the inside convolution (4) of a reel (2) resting horizontally thereupon, the lead-in angle in front of a lead-in point (6) fixed in location is contactlessly measured by reflection of infrared light on both sides of the film strip (5) fed in. In case of deviations of the measurement signal from a nominal value, the reel drive is corrected. A dual infrared LED with reflection light barriers (11, 12) arranged offset in angle and height and approximately focused on the lead-in point (6) is used.

Abstract: The present invention relates pharmaceutical compositions comprising a conjugate of an active substance, a linker and a carrier for the treatment and/or diagnosis of inflammatory diseases. The present invention further relates to methods using such pharmaceutical compositions for treating and diagnosing inflammatory diseases including, but not limited to, infectious diseases, autoimmune diseases, skin diseases, and inflammatory neovascularization.

Abstract: Tumor-active or tumor-diagnostic substances having preferred accumulation in the tumor, which are characterized in that they haveat least two phenolic hydroxyl and/or amino groups,at least one aliphatic amino group, orat least one phenolic hydroxyl and/or amino group andat least one aliphatic amino groupand that these groups are substituted with polyethylene glycol chains whose polymerization degree n is 5 to 250 and whose terminal hydroxyl group is substituted by C.sub.1 -C.sub.12 alkyl ester or ether, each of the substances being substituted by at least two such polyethylene glycol chains.

Abstract: The invention relates to conjugates composed ofa) at least one polyalcohol or a derivatized polyalcohol,b) at least one active agent,c) at least one linker andd) a protein,wherein the polyalcohol(s) or the derivatized polyalcohol(s) are polyalcohols or derivatized polyalcohols which are not recognized by the defense system of an organism as exogenous, and the protein is a protein which can be taken up by the tumor specifically or non-specifically, and is not recognized by the defense system of an organism as exogenous. These conjugates are suitable for, on the one hand, making possible a very sensitive method in nuclear medicine for the diagnosis of tumors and, on the other hand, for example also offering new methods for diagnosing tumors in X-ray diagnosis, computerized tomography, nuclear spin tomography, electron spin resonance spectroscopy or electron microscopy.

Abstract: The invention relates to the use of a substantially clear and at least largely solventless, aqueous, one-component polyurethane dispersion based on the reaction products ofa polyol mixture consisting completely or partly of polypropylene glycol,a mixture of polyfunctional isocyanates consisting completely or partly of .alpha.,.alpha.,.alpha.',.alpha.'-tetramethyl xylene diisocyanate (TMXDI),a functional component capable of salt formation in aqueous solution andoptionally a chain-extending agentas a universal household adhesive and to a process for its production in the absence of inert solvents.