Patents by Inventor Wolfgang Mann

Wolfgang Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12636649
    Abstract: The invention relates to a collecting device (30) for a reaction vessel unit (21), which has a plurality of reaction vessels (37), wherein the reaction vessels (37) each have an opening (38), which lie in a common opening plane (39), wherein the collecting device (30) has a collecting plate (31), which is designed in such a way that it can be arranged or is arranged opposite the openings (38) of the reaction vessels (37) in a centrifuge (1) and is designed such that it rotates with the reaction vessel unit (21) during Centrifuging and liquid emerging from the reaction vessels (37) is collected by the collecting plate (31) due to the centrifugal acceleration.
    Type: Grant
    Filed: February 2, 2023
    Date of Patent: May 26, 2026
    Assignee: BlueCat Solutions GmbH
    Inventors: Wolfgang Mann, Frank Feist
  • Patent number: 12485431
    Abstract: The invention relates to a discharge device (30) for a reaction vessel unit (21) which has a plurality of reaction vessels (37), wherein the reaction vessels (37) each have an opening (38) which lie in a common opening plane (39), wherein the discharge device (30) has a discharge plate (31) which is designed in such a way that it can be arranged or is arranged opposite the openings (38) of the reaction vessels (37) in a centrifuge (1) and is designed such that it rotates with the reaction vessel unit (21) during centrifuging and liquid escaping from the reaction vessels (37) is collected and drained off by the discharge plate (31) due to the centrifugal acceleration. The invention also relates to a centrifuge (1) for cleaning a reaction vessel unit (21), having a drive, a rotor (20) which can be coupled or is coupled to the drive, wherein the rotor (20) is designed to receive the reaction vessel unit (21) with the discharge device (30).
    Type: Grant
    Filed: February 2, 2023
    Date of Patent: December 2, 2025
    Assignee: BlueCatBio GMBH
    Inventors: Wolfgang Heimberg, Frank Feist, Wolfgang Mann
  • Patent number: 12383907
    Abstract: The invention relates to a centrifuge for cleaning a reaction vessel unit and to a method for cleaning such a centrifuge. The centrifuge has a rotor and a rotor chamber, in which the rotor is arranged and mounted, the rotor features a receiving area for receiving the reaction vessel unit. The rotor chamber is limited by a housing, the housing having an outlet to drain the liquid discharged from the reaction vessels and being provided with an inlet for filling the rotor chamber with a cleaning solution in such a way, when the rotor rotates, the rotor 2 is at least partially immersed in the cleaning solution and distributes it in rotor chamber and/or the inlet is designed in such a way that the cleaning solution is distributed in rotor chamber when it is supplied by the rotating rotor.
    Type: Grant
    Filed: September 9, 2022
    Date of Patent: August 12, 2025
    Assignee: BlueCatBio GmbH
    Inventors: Wolfgang Mann, Frank Feist
  • Publication number: 20250153171
    Abstract: The invention relates to a collecting device (30) for a reaction vessel unit (21), which has a plurality of reaction vessels (37), wherein the reaction vessels (37) each have an opening (38), which lie in a common opening plane (39), wherein the collecting device (30) has a collecting plate (31), which is designed in such a way that it can be arranged or is arranged opposite the openings (38) of the reaction vessels (37) in a centrifuge (1) and is designed such that it rotates with the reaction vessel unit (21) during Centrifuging and liquid emerging from the reaction vessels (37) is collected by the collecting plate (31) due to the centrifugal acceleration.
    Type: Application
    Filed: February 2, 2023
    Publication date: May 15, 2025
    Inventors: Wolfgang Mann, Frank Feist
  • Publication number: 20250114801
    Abstract: The invention relates to a discharge device (30) for a reaction vessel unit (21) which has a plurality of reaction vessels (37), wherein the reaction vessels (37) each have an opening (38) which lie in a common opening plane (39), wherein the discharge device (30) has a discharge plate (31) which is designed in such a way that it can be arranged or is arranged opposite the openings (38) of the reaction vessels (37) in a centrifuge (1) and is designed such that it rotates with the reaction vessel unit (21) during centrifuging and liquid escaping from the reaction vessels (37) is collected and drained off by the discharge plate (31) due to the centrifugal acceleration. The invention also relates to a centrifuge (1) for cleaning a reaction vessel unit (21), having a drive, a rotor (20) which can be coupled or is coupled to the drive, wherein the rotor (20) is designed to receive the reaction vessel unit (21) with the discharge device (30).
    Type: Application
    Filed: February 2, 2023
    Publication date: April 10, 2025
    Inventors: Wolfgang Heimberg, Frank Feist, Wolfgang Mann
  • Publication number: 20250041865
    Abstract: A reaction vessel unit having at least one reaction vessel which has a receiving chamber for receiving a liquid, wherein the receiving chamber has a retention area which has such a surface texture and/or shape that due to an adhesive force between the liquid and the retention area and a cohesion within the liquid, the retention area exerts an increased retention effect on the liquid with respect to the surrounding area, so that a predetermined small amount of liquid is retained at or in the retention area when the liquid is removed from the receiving chamber by centrifuging. Further disclosed is a method for selectively removing a liquid from a reaction vessel of the reaction vessel unit by centrifugation and a method for introducing a liquid containing a target substance into a reaction vessel with a guiding system by centrifugation or magnetic or electrostatic interaction.
    Type: Application
    Filed: December 13, 2022
    Publication date: February 6, 2025
    Inventors: Frank Feist, Wolfgang Mann, Konstantin Mann
  • Publication number: 20240359201
    Abstract: The invention relates to a dispensing device with a linear drive for the relative movement of a reaction vessel unit along a dispensing unit with at least two dispensing heads, each of which has at least one dispensing nozzle, so that a reaction vessel unit can be arranged under the dispensing nozzles of the dispensing unit in order to fill at least one reaction vessel of the reaction vessel unit, pumps which are each connected by a liquid line to one of the dispensing heads in order to convey a liquid reagent to the respective dispensing head. The invention is characterised in that a pump valve with a first and a second inlet and an outlet is arranged upstream of each of the two pumps, wherein the outlet can be connected to the respective pump, the first inlet can be connected to a common reagent stock and the second inlet can be connected to an individual reagent stock.
    Type: Application
    Filed: August 15, 2022
    Publication date: October 31, 2024
    Inventors: Wolfgang Mann, Frank Feist
  • Publication number: 20240230632
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Application
    Filed: January 3, 2024
    Publication date: July 11, 2024
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Publication number: 20240142443
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 2, 2024
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Publication number: 20240133875
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Application
    Filed: January 3, 2024
    Publication date: April 25, 2024
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Patent number: 11885798
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, and a loading mechanism with a beam for loading and unloading the centrifuge with the at least one reaction vessel unit.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: January 30, 2024
    Assignee: YANTAI AUSBIO LABORATORIES CO., LTD.
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Patent number: 11885799
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: January 30, 2024
    Assignee: YANTAI AUSBIO LABORATORIES CO., LTD.
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Publication number: 20230393127
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Application
    Filed: August 16, 2023
    Publication date: December 7, 2023
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Patent number: 11738354
    Abstract: A centrifuge for cleaning a reaction vessel unit comprises a rotor and a rotor chamber in which the rotor is positioned and supported in rotary fashion. The rotor chamber is delimited by a housing having a drainage channel beneath the rotor. Adjacent to the channel, the inner surface of the housing is embodied in the form of a funnel that feeds into the channel. This centrifuge does not require a suction pump for suctioning liquids from the rotor chamber. In addition, the centrifuge can be provided with an exchangeable module that delimits the rotor chamber and includes the rotor. The exchangeable module can be exchanged after a predetermined amount of use and replaced with another. It is also possible, however, for the module to be removed from the centrifuge, cleaned, and reinserted.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: August 29, 2023
    Assignee: BlueCatBio GmbH
    Inventors: Wolfgang Mann, Wolfgang Heimberg, Frank Feist, Dong Liang
  • Publication number: 20230077651
    Abstract: The invention relates to a centrifuge for cleaning a reaction vessel unit and to a method for cleaning such a centrifuge. The centrifuge has a rotor and a rotor chamber, in which the rotor is arranged and mounted, the rotor features a receiving area for receiving the reaction vessel unit. The rotor chamber is limited by a housing, the housing having an outlet to drain the liquid discharged from the reaction vessels and being provided with an inlet for filling the rotor chamber with a cleaning solution in such a way, when the rotor rotates, the rotor 2 is at least partially immersed in the cleaning solution and distributes it in rotor chamber and/or the inlet is designed in such a way that the cleaning solution is distributed in rotor chamber when it is supplied by the rotating rotor.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 16, 2023
    Inventors: Wolfgang Mann, Frank Feist
  • Patent number: 11117142
    Abstract: A centrifuge has a rotor and a rotor chamber in which the rotor is arranged and rotatably mounted, wherein the rotor has a receiving region for receiving a reaction vessel unit, and the centrifuge being provided with a loading and unloading device comprising a rigid sliding rod for positioning a reaction vessel unit in or for removing a reaction vessel unit from the rotor, wherein the sliding bar is movably arranged in such a way that it, between a discharge position in which it extends through the rotor in the rotor chamber and a loading position in which it is pulled at least out of the region of the rotor chamber, which is stressed by the rotor during one revolution, and a linear drive for moving the sliding rod between the discharge position and the loading position.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: September 14, 2021
    Assignee: BLUECATBIO GMBH
    Inventors: Wolfgang Mann, Wolfgang Heimberg, Johann Junkersfeld, Matthias Erzberger, Frank Feist
  • Publication number: 20210270826
    Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.
    Type: Application
    Filed: January 19, 2021
    Publication date: September 2, 2021
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Publication number: 20210138485
    Abstract: The present invention relates to a centrifuge for cleaning a reaction vessel unit, comprising a rotor and a rotor chamber in which the rotor is positioned and supported in rotary fashion. The rotor chamber is delimited by a housing having a drainage channel beneath the rotor. Adjacent to the channel, the inner surface of the housing is embodied in the form of a funnel that feeds into the channel. This centrifuge does not require a suction pump for suctioning liquids from the rotor chamber. In addition, the centrifuge can be provided with an exchangeable module that delimits the rotor chamber and includes the rotor. The exchangeable module can be exchanged after a predetermined amount of use and replaced with another. It is also possible, however, for the module to be removed from the centrifuge, cleaned, and re-inserted.
    Type: Application
    Filed: June 20, 2018
    Publication date: May 13, 2021
    Inventors: Wolfgang Mann, Wolfgang Heimberg, Frank Feist, Dong Liang
  • Patent number: 10928387
    Abstract: A centrifuge for washing magnetic beads in a reaction vessel unit that includes at least one opening, having a housing including an inner surface and a drain, a rotor disposed within the housing, the rotor being configured to hold a reaction vessel unit with its opening(s) directed outwardly toward the inner surface of the housing, a motor coupled with the rotor to rotate around a horizontal rotation axis, and a magnetic element arranged in the rotor to apply a magnetic field to one or more reaction vessels of a reaction vessel unit held by the rotor.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: February 23, 2021
    Assignee: YANTAI AUSBIO LABORATORIES CO., LTD.
    Inventors: Zhaoqiang Wang, Wolfgang Mann, Wolfgang Heimberg
  • Patent number: 10895570
    Abstract: The invention relates to a method for determining the result of an agglutination reaction and a microplate used in such a method. Agglutinated and non-agglutinated sample material is separated by means of a separation material such as gel material or a bead matrix in a centrifugation step. Whether an agglutination reaction took place or not is determined by comparing the color intensities and/or the gray levels of images of the top side and the bottom side of the respective reaction vessel. Comparing the color intensities and/or the gray levels of the two images makes the automatic determination reliable and stable. Furthermore, the reaction wells are arranged in a two-dimensional array which provides a high throughput.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: January 19, 2021
    Assignee: Yantai AusBio Laboratories Co., Ltd.
    Inventors: Zhaoqiang Wang, Wolfgang Mann