Patents by Inventor Wolfgang Muetzel

Wolfgang Muetzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5693310
    Abstract: Compounds of general Formula I ##STR1## wherein R.sup.3 is a saturated, unsaturated, straight- or branched-chain or cyclic aliphatic hydrocarbon residue of up to 16 carbon atoms or, if R.sup.4 is a hydrogen atom, a cycloalkyl group or an aryl or aralkyl group optionally substituted by one or several C.sub.1 -C.sub.6 -dialkylamino groups or by one or several C.sub.1 -C.sub.6 -alkoxy groups,R.sup.4 is a hydrogen atom, a saturated, unsaturated, straight- or branched-chain or cyclic hydrocarbon residue of up to 16 carbon atoms, orR.sup.3 and R.sup.4 jointly mean a saturated or unsaturated 5- or 6-membered ring optionally substituted or containing an O, S, N atom or oxo substituent, and Y is COOX or CONR.sub.3 R.sub.4,are valuable complexing agents, complexes or complex salts, e.g., for use as NMR or X-ray diagnostic image-enhancement agents or radioactive diagnostic agents.
    Type: Grant
    Filed: November 19, 1990
    Date of Patent: December 2, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Bernd Raduechel, Hans-Joachim Weinmann, Wolfgang Muetzel, Ulrich Speck
  • Patent number: 5693309
    Abstract: 1. Compounds of general Formula I ##STR1## wherein n and m in each case mean the numbers 0, 1, 2, 3 and 4,X stands for a hydrogen atom and/or a metal ion equivalent of an element of atomic numbers 21-29, 31, 32, 37-39, 42-44, 49 or 57-83,R.sup.1 and R.sup.2, being different, mean in each case a hydrogen atom or a straight-chain, branched, saturated or unsaturated C.sub.0 -C.sub.20 -alkylene group, this alkylene group exhibiting at the end either a second molecule of general Formula I.sub.A or I.sub.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 2, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Julius Deutsch, Heinz Gries, Erich Klieger, Ulrich Niedballa, Franz-Josef Renneke, Jurgen Conrad, Wolfgang Muetzel, Heribert Schmitt-Willich
  • Patent number: 5482700
    Abstract: 1. Compounds of general Formula I ##STR1## wherein n and m in each case mean the numbers 0, 1, 2, 3 and 4,X stands for a hydrogen atom and/or a metal ion equivalent of an element of atomic numbers 21-29, 31, 32, 37-39, 42-44, 49 or 57-83,R.sup.1 and R.sup.2, being different, mean in each case a hydrogen atom or a straight-chain, branched, saturated or unsaturated C.sub.0 -C.sub.20 -alkylene group which optionally contains imino, phenylenoxy, phenylenimino, amido, hydrazido, ester group(s), oxygen, sulfur and/or nitrogen atom(s) and is substituted, if desired, by hydroxy, mercapto, imino, epoxy, oxo, thioxo and/or amino group(s), this alkylene group exhibiting at the end either a second molecule of general Formula I.sub.A or I.sub.B ##STR2## a functional group, or, linked by way of this functional group, a bio- or macromolecule,are valuable diagnostic and therapeutic media.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: January 9, 1996
    Assignee: Schering Aktiengesellschaft
    Inventors: Julius Deutsch, Heinz Gries, Erich Klieger, Ulrich Niedballa, Franz-Josef Renneke, Juergen Conrad, Wolfgang Muetzel
  • Patent number: 4547357
    Abstract: Novel N-hydroxyethylated 2,4,6-triiodoaminoisophthalic acid bistrihydroxybutylamides of Formula (I) ##STR1## wherein R is a trihydroxybutyl residue, are excellently suitable, due inter alia, to their outstanding compatibility and high water solubility, as opacifying compounds in X-ray contrast media for use in X-ray diagnostic examination methods.
    Type: Grant
    Filed: December 20, 1982
    Date of Patent: October 15, 1985
    Assignee: Schering, Aktiengesellschaft
    Inventors: Heinrich Pfeiffer, Wolfgang Muetzel, Ulrich Speck
  • Patent number: 4466442
    Abstract: The useful lifetime and the amount of microbubbles of a size less than 50 .mu.m produced by mechanical agitation of an aqueous liquid employed as an ultrasonic contrast medium are increased by employing a liquid containing dissolved therein a tenside which reduces the surface tension of the liquid and a compound which raises the viscosity of the liquid.
    Type: Grant
    Filed: October 13, 1982
    Date of Patent: August 21, 1984
    Assignee: Schering Aktiengesellschaft
    Inventors: Juergen Hilmann, Rolf-Ruediger Hoffmann, Wolfgang Muetzel, Ingfried Zimmermann
  • Patent number: 4328202
    Abstract: Ionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --CH.sub.2 NH.multidot.Acyl or --CH.sub.2 OH; Y is --NR.sub.3 R.sub.4, --NH.multidot.Acyl or OR.sub.5 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 can be identical or different, and each is hydrogen, C.sub.1-6 - alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, R.sub.5 is C.sub.1-6 alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, and Acyl, which can be the same or different in X and Y, is C.sub.2-6 -alkanoyl or C.sub.2-6 -alkanoyl substituted by 1-4 OH groups and/or by one C.sub.1-3 -alkoxy group, or a physiologically compatible salt thereof with an inorganic or organic base, have valuable properties as X-ray contrast agents.
    Type: Grant
    Filed: January 9, 1981
    Date of Patent: May 4, 1982
    Assignee: Schering, A.G.
    Inventors: Heinz Gries, Heinrich Pfeiffer, Ulrich Speck, Wolfgang Muetzel