Patents by Inventor Wolfgang Pusch

Wolfgang Pusch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10597692
    Abstract: The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or other body fluids. The invention recognizes that blood is not a good environment for the cultivation of microbes and provides a method which (a) largely destroys or dissolves the human particles in body fluids, such as erythrocytes and leukocytes in blood, without impairing the ability of the microbes to reproduce, (b) separates the microbial pathogens from the fluid, (c) cultivates them in a nutrient broth which contains none of the antimicrobial components of the body fluids, (d) separates them from the nutrient broth, and (e) identifies the microbes by a mass spectrum of the microbial proteins. The dissolution of the human particles also releases the microbes nesting in macrophages.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: March 24, 2020
    Assignee: Bruker Daltonik GmbH
    Inventors: Jochen Franzen, Markus Kostrzewa, Thomas Maier, Karsten Michelmann, Wolfgang Pusch
  • Publication number: 20180265909
    Abstract: The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or other body fluids. The invention recognizes that blood is not a good environment for the cultivation of microbes and provides a method which (a) largely destroys or dissolves the human particles in body fluids, such as erythrocytes and leukocytes in blood, without impairing the ability of the microbes to reproduce, (b) separates the microbial pathogens from the fluid, (c) cultivates them in a nutrient broth which contains none of the antimicrobial components of the body fluids, (d) separates them from the nutrient broth, and (e) identifies the microbes by a mass spectrum of the microbial proteins. The dissolution of the human particles also releases the microbes nesting in macrophages.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 20, 2018
    Inventors: Jochen Franzen, Markus Kostrzewa, Thomas Maier, Karsten Michelmann, Wolfgang Pusch
  • Patent number: 10006076
    Abstract: The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or other body fluids. The invention recognizes that blood is not a good environment for the cultivation of microbes and provides a method which (a) largely destroys or dissolves the human particles in body fluids, such as erythrocytes and leukocytes in blood, without impairing the ability of the microbes to reproduce, (b) separates the microbial pathogens from the fluid, (c) cultivates them in a nutrient broth which contains none of the antimicrobial components of the body fluids, (d) separates them from the nutrient broth, and (e) identifies the microbes by a mass spectrum of the microbial proteins. The dissolution of the human particles also releases the microbes nesting in macrophages.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: June 26, 2018
    Assignee: Bruker Daltonik GmbH
    Inventors: Jochen Franzen, Markus Kostrzewa, Thomas Maier, Karsten Michelmann, Wolfgang Pusch
  • Publication number: 20160251694
    Abstract: The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or other body fluids. The invention recognizes that blood is not a good environment for the cultivation of microbes and provides a method which (a) largely destroys or dissolves the human particles in body fluids, such as erythrocytes and leukocytes in blood, without impairing the ability of the microbes to reproduce, (b) separates the microbial pathogens from the fluid, (c) cultivates them in a nutrient broth which contains none of the antimicrobial components of the body fluids, (d) separates them from the nutrient broth, and (e) identifies the microbes by a mass spectrum of the microbial proteins. The dissolution of the human particles also releases the microbes nesting in macrophages.
    Type: Application
    Filed: July 29, 2011
    Publication date: September 1, 2016
    Inventors: Jochen Franzen, Mark Kostrzewa, Thomas Maier, Karsten Michelmann, Wolfgang Pusch
  • Patent number: 7386173
    Abstract: The present invention relates to graphic presentations of complex analytical data strings containing each a multitude of substance-representing peaks (e.g. mass spectra or chromatograms) and pattern recognition or classification techniques in collections of such data strings. The invention proposes to highlight, after execution of the pattern recognition or classification algorithms, the significantly participating peaks in the graphical display so that the nature of these peaks, and the substances represented by these peaks, can easily be further investigated. The content of the graphical display, particularly the peaks, can be interactively accessed by the user and by the pattern recognition programs.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: June 10, 2008
    Assignee: Bruker Daltonik GmbH
    Inventors: Herbert Kaminski, Jan-Henner Wurmbach, Wolfgang Pusch
  • Patent number: 6788947
    Abstract: A first base station, which is coupled to a first switching system part is set up within radio range of a second base station, which is coupled to a second switching system part. After initial synchronization of the first base station to the first switching system part and of the second base station to the second switching system part, the second base station receives radio frames transmitted from the first base station and determines their time error with respect to its own radio frame clock. The determined time error is then transmitted to the second switching system part. In response to this, the second switching system part transmits a synchronization signal to the second base station, with the transmission time being chosen as a function of the transmitted time error such that the radio frame clock of the second base station is synchronized with the radio frames of the first base station by time alignment with the synchronization signal.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: September 7, 2004
    Assignee: Siemens Aktiengesellschaft
    Inventors: Claus-Georg Becker, Philipp Nacke, Wolfram Eberstein, Wolfgang Pusch
  • Publication number: 20030002451
    Abstract: A method for transferring data between at least one read/write device (RWD) and at least one mobile data memory (MDM) in an identification system, using at least one mobile data memory (MDM) that is attached to an object for recording object-related status and/or process data, e.g., in a dispatch, transport and/or manufacturing system for the individual items. According to the method, a time-slot structure for transferring data to the mobile data memory (MDM) is predetermined in the read/write device (RWD).
    Type: Application
    Filed: June 10, 2002
    Publication date: January 2, 2003
    Applicant: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Wolfgang Konrad, Wolfgang Pusch, Martin Schiefer, Peter-Ernst Veith
  • Publication number: 20020082030
    Abstract: A telecommunication device, and associated method, for forwarding messages intended for forwarded-to subscribers, including a database which contains subscriber-related information relating to a number of forwarded-to subscribers and terminals associated with these and message formats compatible with these terminals, and a control device. On reception of a message for a forwarded-to subscriber, the control device selects via the subscriber-related information one or more terminals via which the forwarded-to subscriber can be reached, and message formats which are compatible with these terminals, converts the message with the aid of conversion modules and forwards it to the respective corresponding telecommunication network interface for transmission to the selected terminals.
    Type: Application
    Filed: November 28, 2001
    Publication date: June 27, 2002
    Inventors: Stefan Berndt, Bruno Bozionek, Hans-Juergen Hauschild, Bernd Hinz, Uwe Langer, Manfred Schuetz, Volkmar Bilke, Meint-Uden Carstensen, Dieter Hemkemeyer, Heinz Koopmann, Wolfgang Pusch, Rainer Zimmermann
  • Publication number: 20020072381
    Abstract: A first base station, which is coupled to a first switching system part is set up within radio range of a second base station, which is coupled to a second switching system part. After initial synchronization of the first base station to the first switching system part and of the second base station to the second switching system part, the second base station receives radio frames transmitted from the first base station and determines their time error with respect to its own radio frame clock. The determined time error is then transmitted to the second switching system part. In response to this, the second switching system part transmits a synchronization signal to the second base station, with the transmission time being chosen as a function of the transmitted time error such that the radio frame clock of the second base station is synchronized with the radio frames of the first base station by time alignment with the synchronization signal.
    Type: Application
    Filed: December 3, 2001
    Publication date: June 13, 2002
    Inventors: Claus-Georg Becker, Philipp Nacke, Wolfram Eberstein, Wolfgang Pusch
  • Patent number: 5964840
    Abstract: The workloads (Z, ZS, ZS(X), gn1) of a microprocessor system (MPS), of all signaling channels (D) to the connected communication terminal equipment units (KE) and of a memory element pool (SEP) are measured in subscriber line modules (SLMO) of a communication system (KS). The measured workloads are compared to predetermined workload limits (GZ, GZS, gzn1), and an overload of a subscriber line module (SLMO) is recognized dependent on the comparison results. Designational or summary, fast-acting countermeasures can be initiated on the basis of the early recognition of at least two overloads.
    Type: Grant
    Filed: September 19, 1996
    Date of Patent: October 12, 1999
    Assignee: Siemens Aktiengesellschaft
    Inventors: Peter Stevens, Wolfgang Pusch