Patents by Inventor Wolfgang Rollinger

Wolfgang Rollinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7205118
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: April 17, 2007
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Theresa Kott, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060199232
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PSE3 (proteasome activator subunit 3) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PSE3 in said sample. Measurement of PSE3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: February 7, 2006
    Publication date: September 7, 2006
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060194266
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein RLA-0 (60S acidic ribosomal protein P0) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring RLA-0 in said sample. Measurement of RLA-0 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: February 7, 2006
    Publication date: August 31, 2006
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060188950
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein SPEE (sperrnidine synthase) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring SPEE in said sample. Measurement of SPEE can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: February 7, 2006
    Publication date: August 24, 2006
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060188949
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PLST (T-plastin) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PLST in said sample. Measurement of PLST can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: February 7, 2006
    Publication date: August 24, 2006
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060177880
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PRN3/ILEU and/or unbound PRN3 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PRN3/ILEU and/or unbound PRN3 in said sample. Measurement of PRN3/ILEU and/or unbound PRN3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: January 20, 2006
    Publication date: August 10, 2006
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg, Johann Karl
  • Publication number: 20060121540
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein MASP in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring MASP in said sample. Measurement of MASP can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: November 23, 2005
    Publication date: June 8, 2006
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Publication number: 20060003368
    Abstract: The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
    Type: Application
    Filed: June 14, 2005
    Publication date: January 5, 2006
    Inventors: Michael Tacke, Peter Berndt, Marie-Luise Hagmann, Johann Karl, Theresa Kott, Hanno Langen, Stefan Palme, Markus Roessler, Wolfgang Rollinger, Werner Zolg
  • Patent number: 5976812
    Abstract: The invention concerns activated amphetamine derivatives, a process for their production as well as their use for producing immunogens or detection conjugates carrying amphetamine groups. A further subject matter of the invention are new conjugates carrying amphetamine groups, a process for the production thereof as well as their use for the production of antibodies or for the determination of amphetamine or derivatives thereof.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 2, 1999
    Assignee: Roche Diagnostics GmbH
    Inventors: Erasmus Huber, Christian Klein, Rudolf Vogel, Bruno Zink, Wolfgang Rollinger
  • Patent number: 5646255
    Abstract: Immunogens of formula I are provided for obtaining HbA.sub.1c -specific antibodies ##STR1## M is 1 to 40, T is a carrier protein and A is a 10-20 atoms spacer and is ##STR2## where X is S or --NH--, n is 1 to 4 and B is a succinimide containing organic radical. The antibodies obtained bind glycosylated hemoglobin to determine HbA.sub.1c in body fluids.
    Type: Grant
    Filed: August 15, 1994
    Date of Patent: July 8, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Christian Klein, Christa Hubner-Parajsz, Hans-Georg Batz, Wolfgang Rollinger, Ulrich Essig, Lorenz Kerscher
  • Patent number: 5632993
    Abstract: The present invention provides immunogens for obtaining HbA.sub.1c -specific antibodies, which immunogens have the general formula: ##STR1## wherein M is 1 to 40, T is a carrier protein and A is a spacer which has a chain length of 10 to 20 atoms and has the general formula: ##STR2## wherein X is a sulphur atom or au --NH-- group, n is 1 to 4 and B is an organic radical which contains a succinimide group. The present invention also provides a process for obtaining antibodies which specifically bind glycosylated haemoglobin, wherein an immunogen of general formula (I) is injected into an organism capable of antibody formation and the antibodies are then obtained in known manner. These antibodies can be used for determining HbA.sub.1c in body fluids.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: May 27, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Christian Klein, Christa Hubner-Parajsz, Hans-Georg Batz, Wolfgang Rollinger, Ulrich Essig, Lorenz Kerscher
  • Patent number: 5573922
    Abstract: An immunological method for the determination of triazine and triazine derivatives by a competitive immunoassay in which the sample and labelled atrazine compete for a polyclonal antibody which is bound to a solid phase before, during or after the immunological reaction, the immunological complex binds to the solid phase, the solid phase and unbound labelled atrazine are separated and the label in the solid or liquid phase is determined as a measure of the content of triazine and triazine derivatives, which is characterized in that polyclonal antibodies which were obtained by immunization with a 4-alkylamino-S-triazine are used and a conjugate of a label and 4-amino-S-triazine which is bound to the label via the 6 position is used as the labelled atrazine. Triazine and triazine derivatives can be determined simultaneously using this method.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: November 12, 1996
    Assignee: Boehringer Mannheim GmbH
    Inventors: Eva Hoess, Erasmus Huber, Christine Markert-Hahn, Wolfgang Rollinger