Patents by Inventor Wolfgang Wohlrab

Wolfgang Wohlrab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6719986
    Abstract: The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the invention, the agent is composed of a hyaluronate lyase produced by microbial means and a medicament, preferably a hydrophilic medicament and/or auxiliary substances in different galenic formulations including colloidal carrier systems. The areas of application for the invention in human and veterinary medicament relate to the treatment, prophylaxis and/or metaphylaxis of skin diseases, functional disorders of the skin, the processes of skin ageing and dry skin conditions.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: April 13, 2004
    Assignee: esparma GmbH
    Inventors: Wolfgang Wohlrab, Reinhard Neubert, Christoph Huschka, Peter-Jürgen Müller, Jörg-Herman Ozegowski, Dieter Koegst, Gerhard Fries
  • Patent number: 6689349
    Abstract: The invention relates to an agent for the treatment, prophylaxis and metaphylaxis of functional and structural disorders of the skin caused by external factors. The agent contains a hyaluronic acid partially digested with a microbiological hyaluronate lyase. The hyaluronic acid fragment mixture is incorporated in different galenic formulations to which other hydrophilic and/or lipophilic active substances and/or auxiliary substances can be added. Fields of application of the invention in human and veterinary medicine relate to the treatment and/or the prophylaxis of skin damage caused by environmental factors including UV, dry skin conditions and skin ageing.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: February 10, 2004
    Assignee: esparma GmbH
    Inventors: Wolfgang Wohlrab, Reinhard Neubert, Christoph Huschka, Peter-Jürgen Müller, Jörg-Herman Ozegowski, Dieter Koegst, Gerhard Fries
  • Patent number: 6660251
    Abstract: The invention relates to galenic formulations which contain a) one or more compounds selected from biotin, its physiologically compatible salts, biotin esters and the steroisomeric forms of these compounds; and b) one or more compounds selected from urea and urea derivatives. The above formulations are suitable for use as topically administered formulations for the cosmetic and/or medical treatment of the skin, hair and/or nails.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: December 9, 2003
    Assignee: Merck Patent GmbH
    Inventors: Joachim Bünger, Hansjürgen Driller, Wolfgang Wohlrab, Lothar Motitschke, Christoph Huschka, Reinhard Neubert
  • Publication number: 20030187034
    Abstract: The present invention relates to a composition, comprising
    Type: Application
    Filed: May 23, 2003
    Publication date: October 2, 2003
    Inventors: Joachim Bunger, Hansjurgen Driller, Michael Schwarz, Wolfgang Wohlrab
  • Publication number: 20030157037
    Abstract: The present invention relates to the use of at least one aryl oxime of Formula (I).
    Type: Application
    Filed: November 21, 2002
    Publication date: August 21, 2003
    Inventors: Joachim Bunger, Hansjurgen Driller, Michael Schwarz, Wolfgang Wohlrab
  • Patent number: 6413950
    Abstract: The invention relates to a pharmaceutical preparation in a make-up which is suited for external application and which contains a dithranol derivative as an active ingredient.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: July 2, 2002
    Assignee: esparma GmbH
    Inventors: Jürgen Schneider, Wolfgang Wohlrab, Reinhard Neubert, Christoph Huschka, Dieter Koegst, Gerhard Fries
  • Publication number: 20010038864
    Abstract: A method of producing betulinic acid from the bark of plane trees by fractional extraction with a solvent of medium polarity and subsequent recrystallization out of methanol.
    Type: Application
    Filed: November 30, 2000
    Publication date: November 8, 2001
    Inventors: Birgit Draeger, Tino Galgon, Reinhard Neubert, Wolfgang Wohlrab
  • Patent number: 6175035
    Abstract: A method of producing betulinic acid from the bark of plane trees by fractional extraction with a solvent of medium polarity and subsequent recrystallization out of methanol.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: January 16, 2001
    Inventors: Birgit Draeger, Tino Galgon, Reinhard Neubert, Wolfgang Wohlrab
  • Patent number: 5559098
    Abstract: A stable topical formulation with good active ingredient release characteristics, comprising at least one macrolide antibiotic which is lipophilized with at least one former of oppositely charged ions which is selected from the group consisting of alkyl sulfates, alkylsulfonates, and alkyl salicylates, RX, where R represents a linear and/or branched alkyl group with 6-32 C atoms, and X represents a sulfate, sulfonate, or salicylate group.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: September 24, 1996
    Assignee: Roehm Pharma GmbH
    Inventors: Wolfgang A. Wohlrab, Reinhard Neubert, Sybille Matschiner, Katrin Wellner
  • Patent number: 5476843
    Abstract: A stable topical formulation with good active ingredient release characteristics, comprising at least one macrolide antibiotic which is lipophilized with at least one former of oppositely charged ions which is selected from the group consisting of alkyl sulfates, alkylsulfonates, and alkyl salicylates, RX, where R represents a linear and/or branched alkyl group with 6-32 C atoms, and X represents a sulfate, sulfonate, or salicylate group.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: December 19, 1995
    Assignee: Roehm Pharma GmbH
    Inventors: Wolfgang A. Wohlrab, Reinhard Neubert, Sabine Matschiner, Katrin Wellner
  • Patent number: 5346692
    Abstract: The invention relates to a nail lacquer for treating onychomycosis, comprised of a film-forming agent, an antimycotically active substance, and urea, wherewith the antimycotically active substance and the urea are liberated from the lacquer when the lacquer is applied. A preferred formulation comprises cellulose derivative(s) as film former(s), clotrimazole as the antimycotic (present in the amount of 5-30 wt. % based on the weight of the non-volatile components), urea (present in the amount of 15-60 wt. % based on the weight of the non-volatile components), and dibutyl phthalate as a plasticizer, in a solvent mixture comprised of acetone and ethanol.
    Type: Grant
    Filed: April 8, 1993
    Date of Patent: September 13, 1994
    Assignee: Roehm Pharma GmbH
    Inventors: Wolfgang Wohlrab, Katrin Wellner