Patents by Inventor Wolfram Gaida

Wolfram Gaida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080009548
    Abstract: A method of treating acute pain in a patient in need thereof, the method comprising orally administering to the patient ambroxol or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: September 17, 2007
    Publication date: January 10, 2008
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Publication number: 20060258640
    Abstract: The invention relates to a method for the treatment of chronic pain comprising the administration of a therapeutically effective amount of flibanserin
    Type: Application
    Filed: May 4, 2006
    Publication date: November 16, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Angelo CECI, Franco BORSINI, Wolfram GAIDA
  • Publication number: 20060199867
    Abstract: The invention relates to the use of ambroxol and the pharmacologically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of diseases which are based on a powerful activation of voltage-dependent sodium channels, particularly for the treatment of chronic pain.
    Type: Application
    Filed: May 19, 2006
    Publication date: September 7, 2006
    Applicant: Boehringer Ingelheim Pharma GmbH
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Publication number: 20050014844
    Abstract: A method of treating acute pain in a patient in need thereof, the method comprising orally administering to the patient ambroxol or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: July 9, 2004
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Publication number: 20050014847
    Abstract: A method of treating chronic nociceptive pain, osteoarthritis, irritable bowel syndrome, fibromyalgia, visceral pain, or rheumatoid arthritis in a patient in need thereof, the method comprising administering to the patient ambroxol or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: July 9, 2004
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Publication number: 20050014845
    Abstract: A method of treating epilepsy, with the exception of epileptic states, in a patient in need thereof, the method comprising administering to the patient ambroxol or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: July 9, 2004
    Publication date: January 20, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Patent number: 6770636
    Abstract: Compounds of formula 1, wherein: R1 is hydrogen, hydroxy, CF3, NO2, CN, halogen, C1-C8-alkyl, or C1-C8-alkoxy; R2, R3, and R4 independently of one another are hydrogen, C1-C8-alkyl, hydroxy, NO2, CN, C1-C8-alkoxyl, CF3, or halogen; R5 and R6 independently of one another are hydrogen or a group consisting of C1-C8-alkyl, C2-C8-alkenyl, C3-C8-alkynyl, C3-C8-cycloalkyl, C3-C8-cycloalkyl-C1-C6-alkylene, C5-C8-cycloalkenyl, C5-C8-cycloalkenyl-C1-C6-alkylene, C6-C10-aryl, and C6-C10-aryl-C1-C6-alkylene, each optionally substituted by a group consisting of C1-C6-alkyl, C2-C6-alkenyl, halogen, C1-C6-alkyloxy, —NH2, —NH(C1-C4-alkyl), —N(C1-C4-alkyl)2, hydroxy, ═O, —COOH, —CO—OC1-C4-alkyl, —CONH2, —CONH(C1-C4-alkyl), —CON(C1-C4-alkyl)2, and CF3, or R5 and R6 together with the nitrogen atom are a saturated or unsaturated 5-, 6-, 7-, or 8-membered heterocyclic group optionally containing one or two further heteroatoms consisting of sulfur, o
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: August 3, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Klaus Fuchs, Werner Stransky, Matthias Grauert, Adrian Carter, Wolfram Gaida, Thomas Weiser, Helmut Ensinger
  • Publication number: 20030171391
    Abstract: The invention relates to the use of ambroxol and the pharmacologically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of diseases which are based on a powerful activation of voltage-dependent sodium channels, particularly for the treatment of chronic pain.
    Type: Application
    Filed: January 21, 2003
    Publication date: September 11, 2003
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Wolfram Gaida, Klaus Klinder, Thomas Weiser
  • Publication number: 20030114480
    Abstract: The invention relates to the use of anellated dihydropyridines according to the following formula I, and the salts thereof with physiologically acceptable acids, for the treatment of chronic pain, wherein A is benzo or thieno and Z, R1, R2, R3, R4, R5 and R6 are defined as in the specification: 1
    Type: Application
    Filed: September 11, 2002
    Publication date: June 19, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Dietrich Arndts, Walter Loesel, Wolfram Gaida, Klaus Klinder, Stefan Matthias Blech, Henning Draheim
  • Patent number: 6492377
    Abstract: New imidazotriazolopyrimidine derivatives of the formula Preferred are those compounds wherein: R1 denotes methyl, which is optionally substituted by phenyloxy or pyrrole; or R1 denotes benzyl which is optionally substituted by hydroxy, methoxy, dimethylaminoethoxy or fluorine; or R1 denotes cyclopentyl, furan or phenylethyl; R2 or R3 denote ethyl, n-propyl, allyl or propargyl; R4 or R6 denote hydrogen; and, R5 denotes methyl, n-propyl, tert.butyl, cyclopentyl or norbornenyl. These are adenosine antagonists are are useful for, inter alia, the treatment of senile dementia of the Alzheimer's type.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: December 10, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Stefan Blech, Adrian Carter, Wolfram Gaida, Matthias Hoffmann, Ulrike Kuefner-Muehl, Christopher John Montague Meade, Gerald Pohl, Werner Kummer, Erich Lehr, Joachim Mierau, Thomas Weiser
  • Patent number: 6476047
    Abstract: The invention relates to the use of anellated dihydropyridines according to the following formula I, and the salts thereof with physiologically acceptable acids, for the treatment of chronic pain, wherein A is benzo or thieno and Z, R1, R2, R3, R4, R5 and R6 are defined as in the specification: The inventions also relates to novel compounds of formula I and pharmaceutical compositions thereof.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: November 5, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Dietrich Arndts, Walter Loesel, Wolfram Gaida, Klaus Klinder, Stefan Matthias Blech, Henning Draheim
  • Publication number: 20020058676
    Abstract: Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines of general formula 1: 1
    Type: Application
    Filed: November 27, 2001
    Publication date: May 16, 2002
    Inventors: Matthias Grauert, Adrian Carter, Thomas Weiser, Helmut Ensinger, Wolfram Gaida, Joachim Mierau
  • Patent number: 6387921
    Abstract: Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines of general formula 1: wherein: R1 and R2, which are identical or different, are each hydrogen, C1-C6-alkyl, C1--C6-alkyloxy, OH, F, Cl, or Br; R3 is hydrogen, F, Cl, Br, methyl, ethyl, OH, or methoxy; R4 and R5, which are identical or different, are each hydrogen, methyl, or ethyl; R6 is hydrogen; X is NH2, NH—(C1-C6-alkyl), N(C1-C6-alkyl)2, the two C1-C6-alkyl groups of which are identical or different, NH—COH, NH—CO(C1-C6-alkyl), or F; A is —(CH2)3—, —CH2—CH2—O—, —CH2—O—CH2—, —(CH2)4—, —CH(C1-C6-alkyl)-O—CH2—, —(CH2)2—O—CH2—, —(CH2)3—O—, —(CH2)5—, —CH2—O—(CH2)3—, —(CH2)2—O—(CH2)2—, —(CH2)3—O—CH2—, —(CH2)4—O—, —CH2—O—CH2—CH2—O—,
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: May 14, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Matthias Grauert, Adrian Carter, Thomas Weiser, Helmut Ensinger, Wolfram Gaida, Joachim Mierau
  • Publication number: 20020045640
    Abstract: The invention relates to the use of anellated dihydropyridines according to the following formula I, and the salts thereof with physiologically acceptable acids, for the treatment of chronic pain, wherein A is benzo or thieno and Z, R1, R2, R3, R4, R5 and R6 are defined as in the specification: 1
    Type: Application
    Filed: July 19, 2001
    Publication date: April 18, 2002
    Inventors: Dietrich Arndts, Walter Loesel, Wolfram Gaida, Klaus Klinder, Stefan Matthias Blech, Hennig Draheim
  • Publication number: 20020042410
    Abstract: Compounds of formula 1, 1
    Type: Application
    Filed: July 24, 2001
    Publication date: April 11, 2002
    Inventors: Klaus Fuchs, Werner Stransky, Matthias Grauert, Adrian Carter, Wolfram Gaida, Thomas Weiser, Helmut Ensinger
  • Patent number: 6355652
    Abstract: Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines of general formula 1: wherein: R1 and R2, which may be identical or different, are each hydrogen, C1-C6-alkyl, C1-C6-alkyloxy, OH, F, Cl, or Br; R3 is hydrogen, F, Cl, Br, methyl, ethyl, OH, or methoxy; R4, R5, and R6, which may be identical or different, are each hydrogen, methyl, or ethyl; X is NH2, NH-(C1-C6-alkyl), N(C1-C6-alkyl)2, the two C1-C6-alkyl groups of which may be identical or different, NH—COH, NH—CO(C1-C6-alkyl), or F; A is —(CH2)3—, —CH2—CH2—O—, —CH2—O—CH2—, —(CH2)4—, —CH(C1-C6-alkyl)-O—CH2—, —(CH2)2—O—CH213 , —(CH2)3—O—, —(CH2)5—, —CH2—O—(CH2)3—, —(CH2)2—O—(CH2)2—, —(CH2)3—O—CH2—, —(CH2)4—O—, —CH2—O—CH2—CH2—O—,  the
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: March 12, 2002
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Matthias Grauert, Adrian Carter, Thomas Weiser, Helmut Ensinger, Wolfram Gaida, Joachim Mierau
  • Patent number: 6187780
    Abstract: Asymmetrically substituted xanthine derivatives having adenosine A1 antagonistic activity. These are useful as pharmaceuticals. Exemplary are: (a) 3-(2-(2-acetyloxyethyl)sulphonylethyl)-8-(1-noradamantyl)-1-n-propyl-xanthine; (b) 3-(2-(hydroxyethyl)sulphonylethyl)-8-(1-noradamantyl)-1-n-propyl-xanthine; and, (c) 3-(2-(carbamoylethyl)-8-(1-noradanantyl)-1-n-propyl-xanthine.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: February 13, 2001
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Stefan Blech, Adrian Carter, Wolfram Gaida, Ursula Gath, Matthias Hoffmann, Ulrike Kuefner-Muehl, Erich Lehr, Joachim Mierau, Gerald Pohl, Thomas Weiser
  • Patent number: 5599817
    Abstract: A method for stimulating diuresis comprising administering a composition comprising 8-(3-oxocyclopentyl)-1,3-di-n-propyl-7H-purine-2,6-dione and, optionally, a loop diuretic, is disclosed.
    Type: Grant
    Filed: July 6, 1995
    Date of Patent: February 4, 1997
    Assignee: Boehringer Ingelheim KG
    Inventors: Stefan Adamus, Wolfram Gaida, Christopher Meade, Ulrike K ufner-Muhl
  • Patent number: 5008273
    Abstract: Amino acid derivatives of general formula ##STR1## (the definitions of the various symbols being explained in the specification) are suitable for treating high blood pressure and for cardioprotection. The new compounds are prepared and used in the usual way.
    Type: Grant
    Filed: September 6, 1989
    Date of Patent: April 16, 1991
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gerd Schnorrenberg, Otto Roos, Walter Losel, Ingrid Wiedemann, Wolfram Gaida, Wolfgang Hoefke, Dietrich Arndts, Ilse Streller
  • Patent number: 4997833
    Abstract: Aryloxy-aminoalkanes useful as antihypertensive agents are described and disclosed.
    Type: Grant
    Filed: July 5, 1989
    Date of Patent: March 5, 1991
    Assignee: Boehringer Ingelheim K G
    Inventors: KoHerbert, Franz Esser, Wolfram Gaida, Wolfgang Hoefke, Georg Speck