Patents by Inventor Won-beom PARK

Won-beom PARK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANODISC COMPRISING ANGIOTENSIN CONVERTING ENZYME 2
    Publication number: 20250152681
    Abstract: The present invention relates to a nanodisc comprising angiotensin converting enzyme 2 (ACE2) and a membrane scaffold protein (MSP). In the present invention, the angiotensin converting enzyme 2 (ACE2) is included in the nanodisc, and it was confirmed that the antiviral efficacy and substrate conversion ability of the angiotensin converting enzyme 2 (ACE2) could be significantly improved.
    Type: Application
    Filed: February 10, 2023
    Publication date: May 15, 2025
    Applicants: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, MVRIX Co.,Ltd.
    Inventors: Dae Hyuk KWEON, Jae Hyeon HWANG, Kyeong Won KIM, Jeong Hyeon YOON, Won Beom PARK
  • Method for safely producing botulinum neurotoxin
    Patent number: 12171815
    Abstract: The present invention relates to a method for producing botulinum toxin in various fragments to then be reassembled, for safely producing same. In the present invention, devised is a method in which: botulinum toxin is produced in fragments by cleaving light and heavy chains thereof into two or three pieces, respectively, and then combined as a full-length toxin, thereby allowing high complexity in production, due to toxicity, as well as low safety and economic feasibility, to be overcome; production of water-soluble botulinum toxin is enabled by using bacteria, thereby markedly shortening the production time as compared to existing production methods; and conjugation of the produced fragments with other proteins and nanoparticles is also enabled, thereby increasing the pharmaceutical extensibility of the toxin.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: December 24, 2024
    Assignee: MVRIX CO., LTD.
    Inventors: Dae-Hyuk Kweon, Joon-Bum Park, Yong-Jun Kim, Min-Ju Kim, Won-beom Park
  • METHOD FOR SAFELY PRODUCING BOTULINUM NEUROTOXIN
    Publication number: 20220280617
    Abstract: The present invention relates to a method for producing botulinum toxin in various fragments to then be reassembled, for safely producing same. In the present invention, devised is a method in which: botulinum toxin is produced in fragments by cleaving light and heavy chains thereof into two or three pieces, respectively, and then combined as a full-length toxin, thereby allowing high complexity in production, due to toxicity, as well as low safety and economic feasibility, to be overcome; production of water-soluble botulinum toxin is enabled by using bacteria, thereby markedly shortening the production time as compared to existing production methods; and conjugation of the produced fragments with other proteins and nanoparticles is also enabled, thereby increasing the pharmaceutical extensibility of the toxin.
    Type: Application
    Filed: December 18, 2020
    Publication date: September 8, 2022
    Applicant: MVRIX CO., LTD.
    Inventors: Dae-Hyuk KWEON, Joon-Bum PARK, Yong-Jun KIM, Min-Ju KIM, Won-beom PARK