Abstract: A semiconductor device includes a first interlayer insulating film disposed on a substrate and having a first trench. A first lower conductive pattern fills the first trench and includes first and second valley areas that are spaced apart from each other in a first direction parallel to an upper surface of the substrate. The first and second valley areas are recessed toward the substrate. A second interlayer insulating film is disposed on the first interlayer insulating film and includes a second trench that exposes at least a portion of the first lower conductive pattern. An upper conductive pattern fills the second trench and includes an upper barrier film and an upper filling film disposed on the upper barrier film. The upper conductive pattern at least partially fills the first valley area.

Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating non-alcoholic fatty liver disease or dyslipidemia comprising an aminoalkylbenzothiazepine derivative or a pharmaceutically acceptable salt thereof as an active ingredient.

Abstract: An ECG sensor chip used in a wearable appliance includes; a switch controlled —by a switching signal, an amplifier that amplifies a difference between first and second ECG signals, and a location indicator that generates the switching signal. The switch passes either a first ECG signal or second ECG signal in response to the switching signal.

Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating non-alcoholic fatty liver disease or dyslipidemia comprising an aminoalkylbenzothiazepine derivative or a pharmaceutically acceptable salt thereof as an active ingredient.

Abstract: An ECG sensor chip used in a wearable appliance includes; a switch controlled by a switching signal, an amplifier that amplifies a difference between first and second ECG signals, and a location indicator that generates the switching signal. The switch passes either a first ECG signal or second ECG signal in response to the switching signal.

Abstract: An ECG sensor chip used in a wearable appliance includes; a switch controlled by a switching signal, an amplifier that amplifies a difference between first and second ECG signals, and a location indicator that generates the switching signal. The switch passes either a first ECG signal or second ECG signal in response to the switching signal.

Abstract: The present invention relates to a novel aminoalkylbenzothiazepine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing or treating constipation comprising the same as an active ingredient.

Abstract: The present invention relates to a pyrrolopyridazine derivative represented by Formula 1 of the detailed description, or a pharmaceutically acceptable salt thereof. The compound according to the present invention and a pharmaceutically acceptable salt thereof can inhibit the activity of protein kinase(s), and thus are useful for preventing or treating diseases related thereto.

Abstract: The present invention relates to a novel aminoalkylbenzothiazepine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for preventing or treating constipation comprising the same as an active ingredient.

Abstract: An ECG sensor chip used in a wearable appliance includes; a switch controlled by a switching signal, an amplifier that amplifies a difference between first and second ECG signals, and a location indicator that generates the switching signal. The switch passes either a first ECG signal or second ECG signal in response to the switching signal.

Abstract: A regulator circuit includes an OP-amp, buffer, power transistor, voltage divider, load, and feedback current generator. The OP-amp generates first voltage signal by amplifying a difference between an input voltage signal and a feedback voltage signal. The OP-amp drives a first node as the first voltage signal. The buffer drives a second node as a second voltage signal generated based on the first voltage signal. The power transistor includes a drain terminal receiving a supply voltage, a gate terminal connected to the second node, and a source terminal connected to a third node. The voltage divider generates the feedback voltage signal by dividing an output voltage signal of the third node. The load includes a terminal connected to the third node and another terminal receiving a ground voltage. The feedback current generator provides a first feedback current corresponding to a ripple of the output voltage signal to the first node for enhancing a speed at which the ripple reduced.

Abstract: An electrocardiogram (ECG) sensor includes a motion artifact detector configured to detect a motion artifact component from a first channel signal of a first channel and a second channel signal of a second channel using a channel offset coefficient. The channel offset coefficient indicates a difference between the first channel signal and the second channel signal. The ECG sensor includes an ECG filter configured to generate an ECG signal by performing a least mean square (LMS) filtering operation on the first channel signal to remove the motion artifact component.

Abstract: The present invention relates to a pyrrolopyridazine derivative represented by Formula 1 of the detailed description, or a pharmaceutically acceptable salt thereof. The compound according to the present invention and a pharmaceutically acceptable salt thereof can inhibit the activity of protein kinase(s), and thus are useful for preventing or treating diseases related thereto.

Abstract: An electrocardiogram (ECG) sensor includes a motion artifact detector configured to detect a motion artifact component from a first channel signal of a first channel and a second channel signal of a second channel using a channel offset coefficient. The channel offset coefficient indicates a difference between the first channel signal and the second channel signal. The ECG sensor includes an ECG filter configured to generate an ECG signal by performing a least mean square (LMS) filtering operation on the first channel signal to remove the motion artifact component.

Abstract: A mover assembly of a reciprocating motor includes: a mover body disposed at a gap between an inner stator and an outer stator; permanent magnets fixed at an outer circumferential surface of the mover body and reciprocally moved together with the mover body in a direction of an induction magnetic field between the inner stator and the outer stator; and a mixed member made of a fiber and a resin to cover and fix the permanent magnets. The permanent magnets are arranged at an outer circumferential face of the mover body, covered with the mixed member obtained by mixing a fiber and a resin, and hardened to be fixed. Therefore, the permanent magnets can be firmly and easily fixed at the mover body. In addition, by molding the mover body with a non-magnetic and non-conductive material, leakage of the magnetic force of the permanent magnets can be prevented.

Abstract: The present invention provides a novel process for preparing a compound represented by the above formula 7, which is an important intermediate for an oral thrombin inhibitor, by one-pot reaction. In accordance with the present invention, the above intermediate for the thrombin inhibitor may be obtained in a high yield.

Abstract: The present invention relates to a compound having formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I and pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagulants.

Abstract: The present invention relates to novel thrombin inhibitors that are useful as anticoagulants. More particularly, the present invention is directed to peptide derivatives having high antithrombotic activity and high oral bioavailability.

Abstract: The present invention provides a novel process for preparing a compound represented by the above formula 7, which is an important intermediate for an oral thrombin inhibitor, by one-pot reaction. In accordance with the present invention, the above intermediate for the thrombin inhibitor may be obtained in a high yield.