Abstract: The present invention relates to a monoclonal antibody or a fragment thereof that recognizes and binds specifically to the extracellular domain of endothelin receptor type A as an antigen. The monoclonal antibody of the present invention is suitable for use in a therapeutic agent for hypertension or cancer associated with endothelin receptor type A.

Abstract: A method for accurately searching a target track of a disc in a disc drive is provided. The method includes the steps of: a) generating a reference signal having a predetermined period, b) moving a pickup across tracks from a starting point of a disc region where information is recorded to an end point thereof, c) counting the number of pulses of the reference signal generated during the movement and the number of tracks across which the pickup moves, d) dividing the counted number of tracks by the counted number of pulses of the reference signal, thereby obtaining the number of tracks per reference signal pulse, and e) searching a target track based on the number of tracks per reference signal pulse in the step d). Here, both the total number of tracks between a starting point of a program region and a starting point of a lead-out region and the number of pulses of a reference signal is obtained, and the number of tracks per reference signal pulse is obtained from the data.