Abstract: A gene amplification chip includes a chamber layer, a cover layer, a bottom layer, an inlet, and an outlet. The chamber layer has a first passage and through holes which are formed on one side of the first passage. The cover layer is disposed on one side of the chamber layer and has a cover channel formed to communicate with the first passage and the through holes, wherein the cover channel, the first passage and the through holes allow passage of liquids in a divided manner. The bottom layer is disposed on another side of the chamber layer and has a bottom channel formed to communicate with the first passage and the through holes. The inlet is formed in the cover layer and communicates with the cover channel. The outlet communicates with any one of the cover channel and the bottom channel.

Abstract: The present disclosure provides a caricature generation method capable of expressing detailed and realistic facial exaggerations and allowing a reduction of training labor and cost. A caricature generating method includes: providing a generation network comprising a plurality of layers connected in series including coarse layers of lowest resolutions and pre-trained to be suitable for synthesizing a shape of a caricature and fine layers of highest resolutions and pre-trained to be suitable for tuning a texture of the caricature; applying input feature maps representing an input facial photograph to the coarse layers to generate shape feature maps and deforming the shape feature maps by shape exaggeration blocks to generate deformed shape feature maps; applying the deformed shape feature maps to the fine layers to change a texture represented by the deformed shape feature maps and generate output feature maps; and generating a caricature image according to the output feature map.