Patents by Inventor WonHyoung Ryu
WonHyoung Ryu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11697009Abstract: Disclosed are a microneedle patch and a method for fabricating the microneedle patch. The microneedle patch includes a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and a microneedle array disposed on the base layer. The method includes forming a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and forming a microneedle array on the base layer.Type: GrantFiled: September 4, 2020Date of Patent: July 11, 2023Assignee: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: WonHyoung Ryu, SeungHyun Park, JiYong Lee, Jae Ho Kim
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Publication number: 20230080643Abstract: There is provided a microneedle patch. The microneedle patch includes: a plurality of microneedles each having an upper end portion and a base portion and which are individualized from each other; and a base layer that is formed of a water-soluble material and includes linear portions that pass the base portions of the microneedles neighboring each other among the plurality of microneedles and are joined to the base portions of the microneedles neighboring each other.Type: ApplicationFiled: November 18, 2022Publication date: March 16, 2023Applicant: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: WonHyoung RYU, SeungHyun PARK, JiYong LEE, Jae Ho KIM
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Publication number: 20220142579Abstract: Provided are an apparatus for acquiring biological data and an apparatus for processing biological data. The apparatus for being inserted into a living body and acquiring biological information includes a balloon inserted into the living body to expand or contract, one or more electrodes disposed on a surface of the balloon, and one or more fine protrusions disposed on surfaces of the electrodes to come into contact with the living body.Type: ApplicationFiled: November 5, 2021Publication date: May 12, 2022Applicant: UIF (University Industry Foundation), Yonsei UniversityInventors: Wonhyoung RYU, Jiyong LEE, Jeong Min KIM
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Publication number: 20210069482Abstract: Disclosed are a microneedle patch and a method for fabricating the microneedle patch. The microneedle patch includes a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and a microneedle array disposed on the base layer. The method includes forming a base layer including a mesh structure or auxetic materials having a negative Poisson's ratio, and forming a microneedle array on the base layer.Type: ApplicationFiled: September 4, 2020Publication date: March 11, 2021Applicant: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: WonHyoung RYU, SeungHyun PARK, JiYong LEE, Jae Ho KIM
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Patent number: 9409772Abstract: A reaction hydrogen production control mechanism is provided that includes, a solid sodium borohydride mixture, a liquid fuel reactant, at least one liquid delivery medium (LDM), a movable boundary interface (MBI) and a reaction zone, where the MBI is disposed to provide a constant contact between a reacting surface of the solid fuel mixture and the primary LDM to form the reaction zone. A reaction in the reaction zone includes a hydrolysis reaction. The MBI moves according to a spring, gas pressure, or an elastic membrane. Product paths are disposed to transfer reactants from the system. The product paths can include a channel on a surface of the solid fuel mixture, a channel disposed through the solid fuel mixture, a channel disposed about the solid fuel mixture, a contained region disposed about the solid fuel mixture, or a conduit abutting the solid fuel mixture.Type: GrantFiled: April 22, 2014Date of Patent: August 9, 2016Assignee: Intelligent Energy LimitedInventors: Daniel Braithwaite, Wonhyoung Ryu, Courtney Aline Helland, Kei E Yamamoto, Andrew Philip Peterson, Matthieu Jonemann, Adam Naegeli Rodriguez, Gabriel Jose Parisi-Amon
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Publication number: 20140227170Abstract: A reaction hydrogen production control mechanism is provided that includes, a solid sodium borohydride mixture, a liquid fuel reactant, at least one liquid delivery medium (LDM), a movable boundary interface (MBI) and a reaction zone, where the MBI is disposed to provide a constant contact between a reacting surface of the solid fuel mixture and the primary LDM to form the reaction zone. A reaction in the reaction zone includes a hydrolysis reaction. The MBI moves according to a spring, gas pressure, or an elastic membrane. Product paths are disposed to transfer reactants from the system. The product paths can include a channel on a surface of the solid fuel mixture, a channel disposed through the solid fuel mixture, a channel disposed about the solid fuel mixture, a contained region disposed about the solid fuel mixture, or a conduit abutting the solid fuel mixture.Type: ApplicationFiled: April 22, 2014Publication date: August 14, 2014Applicant: Intelligent Energy LimitedInventors: Daniel Braithwaite, Wonhyoung Ryu, Courtney Aline Helland, Kei E. Yamamoto, Andrew Philip Peterson, Matthieu Jonemann, Adam Naegeli Rodriguez, Gabriel Jose Parisi-Amon
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Patent number: 8741004Abstract: A reaction hydrogen production control mechanism is provided that includes, a solid sodium borohydride mixture, a liquid fuel reactant, at least one liquid delivery medium (LDM), a movable boundary interface (MBI) and a reaction zone, where the MBI is disposed to provide a constant contact between a reacting surface of the solid fuel mixture and the primary LDM to form the reaction zone. A reaction in the reaction zone includes a hydrolysis reaction. The MBI moves according to a spring, gas pressure, or an elastic membrane. Product paths are disposed to transfer reactants from the system. The product paths can include a channel on a surface of the solid fuel mixture, a channel disposed through the solid fuel mixture, a channel disposed about the solid fuel mixture, a contained region disposed about the solid fuel mixture, or a conduit abutting the solid fuel mixture.Type: GrantFiled: July 9, 2010Date of Patent: June 3, 2014Assignee: Intelligent Energy LimitedInventors: Daniel Braithwaite, Wonhyoung Ryu, Courtney Aline Helland, Kei E. Yamamoto, Andrew Philip Peterson, Matthieu Jonemann, Adam Naegeli Rodriguez, Gabriel Parisi-Amon
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Publication number: 20110200495Abstract: A reaction hydrogen production control mechanism is provided that includes, a solid sodium borohydride mixture, a liquid fuel reactant, at least one liquid delivery medium (LDM), a movable boundary interface (MBI) and a reaction zone, where the MBI is disposed to provide a constant contact between a reacting surface of the solid fuel mixture and the primary LDM to form the reaction zone. A reaction in the reaction zone includes a hydrolysis reaction. The MBI moves according to a spring, gas pressure, or an elastic membrane. Product paths are disposed to transfer reactants from the system. The product paths can include a channel on a surface of the solid fuel mixture, a channel disposed through the solid fuel mixture, a channel disposed about the solid fuel mixture, a contained region disposed about the solid fuel mixture, or a conduit abutting the solid fuel mixture.Type: ApplicationFiled: July 9, 2010Publication date: August 18, 2011Inventors: Daniel Braithwaite, Wonhyoung Ryu, Courtney Aline Helland, Kei E. Yamamoto, Andrew Philip Peterson, Matthieu Jonemann, Adam Naegeli Rodriguez, Gabriel Jose Parisi-Amon
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Publication number: 20110020215Abstract: A chemical hydride liquid reactant distribution mixture is provided. The mixture includes a fuel mixture having at least one hydride and at least one activating agent. The invention further includes a liquid-distributing agent (LDA), a form-stabilizing agent, and at least one anti-caking agent. The liquid reactant distribution mixture reduces caking and precipitation while promoting liquid reactant distribution, where the chemical hydride liquid reactant distribution mixture generates hydrogen via hydrolysis.Type: ApplicationFiled: July 23, 2009Publication date: January 27, 2011Inventors: WonHyoung Ryu, Daniel Braithwaite, Tibor Fabian
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Publication number: 20090227938Abstract: Provided herein is a wound closure device comprising a plug adaptable to be inserted into an opening formed in two or more tissue layers, one tissue layer transposable relative to a second layer, the plug comprising a material having a first configuration and a second configuration, wherein the plug is adaptable to be inserted into the opening in the first configuration and further adaptable to transition from the first configuration to the second configuration after being inserted into the opening. The wound closure device can be used in cases where ocular surgery has been preformed.Type: ApplicationFiled: October 7, 2008Publication date: September 10, 2009Applicant: InSitu Therapeutics, Inc.Inventors: Rainer Fasching, WonHyoung Ryu, Darius Moshfeghi
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Patent number: 7557051Abstract: Methods for compression molding through holes in polymer layers are provided, as are the resulting patterned polymer layers. Two key aspects of the invention are provision of a mold and substrate having different mechanical hardness, and provision of room for local flow of material. These aspects of the invention facilitate formation of through holes by compression molding that are not blocked or partially blocked by undesirable material. These polymer layers can be formed into three dimensional patterned structures by bonding patterned layers together. Since the layers include through holes, a three-dimensional polymer pattern can be formed. These patterned polymer layers and three dimensionally patterned polymer constructs have a wide variety of applications. For example, these constructs can be used for fabrication of micro-fluidic devices, and/or can be used for various medical and biological applications including drug delivery devices and tissue engineering devices.Type: GrantFiled: March 11, 2005Date of Patent: July 7, 2009Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: WonHyoung Ryu, Seoung Jai Bai, Kyle Hammerick, Robert Lane Smith, Ralph S. Greco, Friedrich B. Prinz, Rainer J. Fasching
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Publication number: 20090087380Abstract: Multi-layered polymer devices having three-dimensional containers for holding a therapeutic and/or imaging agent are provided. The devices have a high loading ratio of agent to polymer material for effective treatment. Delivery wings or regions with channels connected to the containers are also incorporated in the devices. The delivery wings can be flexible and insertable into hollow instruments, such as a needle. Anchoring structures are also provided for fixing the position of the device after injection into a subject. The polymer layers of the device can be biodegradable. Biodegradable materials can also be used to provide controlled release of agents, such as for immunizations and other therapeutic or non-therapeutic applications.Type: ApplicationFiled: September 17, 2008Publication date: April 2, 2009Inventors: Rainer J. Fasching, WonHyoung Ryu
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Patent number: 7422191Abstract: A bistable minivalve includes a movable component, an actuator that is electrostatically, magnetically, or mechanically coupled to the movable component for controllably switching the movable component between open and closed states, and a casing providing structural support. The movable component has an actuation surface [300] movably positioned in the valve conduit and a bistable element attached to the actuation surface providing mechanical stability to the open and closed states of the movable component. The bistable element may be realized as a pair of elastic buckling beams [302, 304] attached at their midpoints to opposite sides of the actuation surface. Optionally, there may also be elastic support beams [306, 308] attached at their endpoints to the actuation surface and attached at their midpoints to the elastic buckling beams.Type: GrantFiled: June 10, 2005Date of Patent: September 9, 2008Assignees: The Board of Trustees of the Leland Stanford Junior University, Honda Motor Co., Ltd.Inventors: Dino Accoto, Friedrich B. Prinz, Tibor Fabian, WonHyoung Ryu, Jun Sasahara, Hideaki Tsuru, Georg Brasseur
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Publication number: 20060269475Abstract: Improved controlled therapy is provided with a polymer multi-layer structure having a predetermined micro-fabricated spatial pattern (e.g., reservoirs and channels). More specifically, all geometrical details of the spatial pattern are substantially predetermined. The increased control of pattern geometry provided by the invention allows for improved control of therapy. In preferred embodiments, the polymer multi-layer structure of the invention is biodegradable, but has an in vivo lifetime that is greater than the duration of the therapy being provided. Thus, the geometrical pattern of the polymer structure that controls delivery of the therapy persists without significant change during therapy, and the structure degrades after completion of therapy. In this manner, possible interference of degradation by-products with therapy is minimized, and delivery of therapy does not depend on details of how degradation proceeds.Type: ApplicationFiled: April 11, 2006Publication date: November 30, 2006Inventors: WonHyoung Ryu, Rainer Fasching, Friedrich Prinz, Ralph Greco
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Publication number: 20060017534Abstract: A bistable minivalve includes a movable component, an actuator that is electrostatically, magnetically, or mechanically coupled to the movable component for controllably switching the movable component between open and closed states, and a casing providing structural support. The movable component has an actuation surface [300] movably positioned in the valve conduit and a bistable element attached to the actuation surface providing mechanical stability to the open and closed states of the movable component. The bistable element may be realized as a pair of elastic buckling beams [302, 304] attached at their midpoints to opposite sides of the actuation surface. Optionally, there may also be elastic support beams [306, 308] attached at their endpoints to the actuation surface and attached at their midpoints to the elastic buckling beams.Type: ApplicationFiled: June 10, 2005Publication date: January 26, 2006Inventors: Dino Accoto, Friedrich Prinz, Tibor Fabian, WonHyoung Ryu, Jun Sasahara, Hideaki Tsuru, Georg Brasseur
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Publication number: 20050206048Abstract: Methods for compression molding through holes in polymer layers are provided, as are the resulting patterned polymer layers. Two key aspects of the invention are provision of a mold and substrate having different mechanical hardness, and provision of room for local flow of material. These aspects of the invention facilitate formation of through holes by compression molding that are not blocked or partially blocked by undesirable material. These polymer layers can be formed into three dimensional patterned structures by bonding patterned layers together. Since the layers include through holes, a three-dimensional polymer pattern can be formed. These patterned polymer layers and three dimensionally patterned polymer constructs have a wide variety of applications. For example, these constructs can be used for fabrication of micro-fluidic devices, and/or can be used for various medical and biological applications including drug delivery devices and tissue engineering devices.Type: ApplicationFiled: March 11, 2005Publication date: September 22, 2005Inventors: WonHyoung Ryu, Seoung Bai, Kyle Hammerick, Robert Smith, Ralph Greco, Friedrich Prinz, Rainer Fasching
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Publication number: 20050208271Abstract: Solvent bonding by exposure to a solvent vapor is provided. Vapor phase solvent bonding provides accurate and precise control of the amount of solvent provided to the polymer bodies or objects being bonded. Such precision control of solvent quantity enables solvent bonding to be performed in a manner that does not damage or destroy micro-patterns present in the polymer bodies being bonded. Vapor solvent bonding can be performed in two regimes: saturated and linear. In the saturated regime, the temperature of a polymer body surface is less than the condensation temperature of a polymer vapor. Thus, a liquid condensate will tend to form in this regime. In the linear regime, the temperature of a polymer body surface is greater than the condensation temperature of the polymer vapor. Although a liquid condensate will not form, bonding can still be performed.Type: ApplicationFiled: March 16, 2005Publication date: September 22, 2005Inventors: Rainer Fasching, WonHyoung Ryu, Friedrich Prinz