Patents by Inventor WonSun Yoo

WonSun Yoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lyophilized DNA formulations for enhanced expression of plasmid DNA
    Patent number: 8389492
    Abstract: The present invention provides for a method of treating or preventing ischemic or liver disease in a subject by administering a composition reconstituted from a lyophilized hepatocyte growth factor (HGF) DNA formulation, where the DNA formulation comprises an HGF plasmid DNA, salt and a carbohydrate. The invention further provides for a method of making such a lyophilized DNA formulation that preserves or enhances gene expression both in vitro and in vivo, thus maintaining or stimulating the biological activity of the expressed protein. The invention also provides for the DNA formulation, or the lyophilized DNA formulation according to the methods disclosed.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: March 5, 2013
    Assignee: ViroMed Co., Ltd.
    Inventors: Jong-Mook Kim, Sujeong Kim, Woong Hahn, WonSun Yoo
  • LYOPHILIZED DNA FORMULATIONS FOR ENHANCED EXPRESSION OF PLASMID DNA
    Publication number: 20110166211
    Abstract: The present invention provides for a method of treating or preventing ischemic or liver disease in a subject by administering a composition reconstituted from a lyophilized hepatocyte growth factor (HGF) DNA formulation, where the DNA formulation comprises an HGF plasmid DNA, salt and a carbohydrate. The invention further provides for a method of making such a lyophilized DNA formulation that preserves or enhances gene expression both in vitro and in vivo, thus maintaining or stimulating the biological activity of the expressed protein. The invention also provides for the DNA formulation, or the lyophilized DNA formulation according to the methods disclosed.
    Type: Application
    Filed: March 10, 2011
    Publication date: July 7, 2011
    Inventors: JONG-MOOK KIM, Sujeong Kim, Woong Hahn, WonSun Yoo
  • Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA
    Publication number: 20090258932
    Abstract: The present invention provides for a method of treating or preventing ischemic or liver disease in a subject by administering a composition reconstituted from a lyophilized hepatocyte growth factor (HGF) DNA formulation, where the DNA formulation comprises an HGF plasmid DNA, salt and a carbohydrate. The invention further provides for a method of making such a lyophilized DNA formulation that preserves or enhances gene expression both in vitro and in vivo, thus maintaining or stimulating the biological activity of the expressed protein. The invention also provides for the DNA formulation, or the lyophilized DNA formulation according to the methods disclosed.
    Type: Application
    Filed: April 9, 2009
    Publication date: October 15, 2009
    Inventors: JONG-MOOK KIM, SUJEONG KIM, WOONG HAHN, WONSUN YOO