Abstract: The present disclosure relates to novel cell penetrating peptides and their applications in cosmetic compositions. These compositions include cell penetrating botulinum toxin recombinant proteins, which are fusion proteins of the cell-penetrating peptides and botulinum toxin. Also disclosed are polynucleotides encoding these recombinant proteins and recombinant expression vectors comprising these polynucleotides. The cell penetrating botulinum toxin recombinant proteins serve as active ingredients in the cosmetic compositions.

Abstract: Disclosed herein is a recombinant protein including botulinum toxin and cell penetrating peptides and cosmetic composition. The cell penetrating peptide according to the present disclosure may be actively used as a topical agent for various disease treatment, aesthetic, or cosmetic purposes, especially for a cosmetic composition, by securing better convenience as well as maximizing the intrinsic in vivo efficacy of the botulinum toxin through the cell penetrating recombinant proteins that combines the botulinum toxin and a cell penetrating peptide by making skin penetration and/or cell penetration for botulinum toxin more efficient.

Abstract: Disclosed herein is a cosmetic composition including novel cell penetrating peptides, cell penetrating botulinum toxin recombinant proteins in which the cell-penetrating peptide and botulinum toxin are fused, polynucleotides encoding the cell penetrating botulinum toxin recombinant proteins, recombinant expression vector comprising the polynucleotides, and the cell penetrating botulinum toxin recombinant protein as active ingredients.

Abstract: Disclosed herein is a recombinant protein including botulinum toxin and cell penetrating peptides and cosmetic composition. The cell penetrating peptide according to the present disclosure may be actively used as a topical agent for various disease treatment, aesthetic, or cosmetic purposes, especially for a cosmetic composition, by securing better convenience as well as maximizing the intrinsic in vivo efficacy of the botulinum toxin through the cell penetrating recombinant proteins that combines the botulinum toxin and a cell penetrating peptide by making skin penetration and/or cell penetration for botulinum toxin more efficient.

Abstract: An organic light emitting diode (OLED) display that includes a panel assembly outputting an image, an electrode part formed at one side of the panel assembly, and a connection member connected to the electrode part, wherein the connection member includes a body part having a plane shape, a plurality of first electrode lines and a plurality of second electrode lines extending in a longitudinal direction, being wire bonded to the electrode part, spaced apart from one another in a lateral direction in an alternating manner and electrically connecting an external device to the panel assembly.

Abstract: An organic light emitting diode (OLED) display that includes a panel assembly outputting an image, an electrode part formed at one side of the panel assembly, and a connection member connected to the electrode part, wherein the connection member includes a body part having a plane shape, a plurality of first electrode lines and a plurality of second electrode lines extending in a longitudinal direction, being wire bonded to the electrode part, spaced apart from one another in a lateral direction in an alternating manner and electrically connecting an external device to the panel assembly.