Abstract: A composition according to the present invention, when used alone, is capable of inhibiting the growth of anticancer drug-resistant cancer by overcoming anticancer drug resistance or enhancing anticancer drug sensitivity, and when co-administered with an anticancer drug, may be used very effectively for the prevention, alleviation or treatment of various cancers, especially anticancer drug-resistant cancer.

Abstract: The present invention relates to a novel naphthyridinone derivative compound, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof, which are each relevant to a compound for inhibiting ENPP1, a composition for inhibiting ENPP1, and a method for inhibiting ENPP1.

Abstract: A composition according to the present invention is capable of inhibiting the growth of cancer cells and cancer stem cells, and also is capable of very effectively inhibiting the metastasis of cancer cells to other tissues. Thus, the composition may be very effectively used not only for the prevention, amelioration or treatment of cancer, but also for the inhibition of cancer metastasis.

Abstract: The present disclosure relates to a serum exosomal SF3B4 marker composition for diagnosing early stage hepatocellular carcinoma for noninvasive in vitro diagnosis, wherein, by analyzing an expression level of SF3B4 in plasma proteins as well as expression of SF3B4 in exosomes present in sera of hepatocellular carcinoma patients, the possibility as the most suitable liquid biopsy marker was identified, and a new noninvasive biomarker with high diagnostic accuracy in early stage hepatocellular carcinoma for which no reliable biomarker exists at this present was discovered. As such, by using exosomes to identify cancer cell genomes and proteomes without biopsy, the exosomes are highly applicable in the future as a diagnostic biomarker that is useful in a disease group with a high risk in the biopsy such as hepatocellular carcinoma.

Abstract: The present disclosure relates to an LED board with a stacked structure, which includes: a metal plate; a printed circuit board attached onto an upper side of the metal plate and having at least one through-hole exposing a part of the upper side of the metal plate; at least one LED chip mounted on the metal plate exposed through the through-hole; a stacked portion having a phosphor-accommodating hole larger than the through-hole formed to include the LED chip and coupled onto the printed circuit board; and a phosphor filled in the phosphor-accommodating hole to cover the LED chip.

Abstract: Disclosed is a self-healing acrylic copolymer represented by Formula 1: The acrylic copolymer can self-heal structural damages such as scratches with the aid of heat and water and possesses excellent physical properties at room temperature. Also disclosed is a crosslinked copolymer prepared from the acrylic copolymer.

Abstract: Disclosed is a self-healing acrylic copolymer represented by Formula 1: The acrylic copolymer can self-heal structural damages such as scratches with the aid of heat and water and possesses excellent physical properties at room temperature. Also disclosed is a crosslinked copolymer prepared from the acrylic copolymer.

Abstract: A method for the biological control of Lasioderma serricorne and a method for the mass rearing of Anisopteromalus apiovorus are disclosed. The method for the biological control of Lasioderma serricorne includes introducing Anisopteromalus apiovorus, which is a natural enemy of Lasioderma serricorne, to a source of Lasioderma serricorne. The method for the mass rearing of Anisopteromalus apiovorus includes inducing Anisopteromalus apiovorus to lay eggs on larvae of Lasioderma serricorne, and allowing the eggs laid by the Anisopteromalus apiovorus to emerge into adult insects.

Abstract: A method of treating a surface of a substrate using modified urushiol derived from Toxicodendron vernicifluum is provided. More particularly, the reactivity of a hydroxyl group of urushiol extracted from fresh Toxicodendron vernicifluum is removed before the lacquer is used as a UV coating agent for a substrate such as a steel sheet. Therefore, the substrate may have high antibacterial activity, and excellent appearance and functionalities such as far-infrared radiation, blocking of electromagnetic waves, enhanced corrosion resistance, high crosslinking speed when a low content of a photoinitiator is used, excellent surface gloss and high scratch resistance.

Abstract: The present invention relates to an organic-inorganic nanocomposite comprising a polymer having temperature dependent volume phase transition characteristics, and magnetic particles embedded in the polymer, and a preparation method thereof. The present invention induces more rapid adsorption and desorption of metal ions and can effectively recover the used organic-inorganic nanocomposite.

Abstract: The present invention relates to a calcium carbonate having a surface charge, the preparing process thereof and filler for producing a paper using the same. The present invention provides the process of preparing a calcium carbonate having a surface charge, characterized in that it comprises the following steps of: preparing a solution mixture of one or more monomer selected from the group consisting of calcium hydroxide, acrylic acid, acrylamide, or [2-(acryloyloxy)ethyl]-trimethylammonium chloride; removing dissolved gases such as oxygen and carbon dioxide in the said solution by injecting nitrogen (N2) gas; adjusting pH of the said solution; and inducing a reaction by adding polymerization initiator of a high molecule while injecting carbon dioxide to the said mixture.

Abstract: The present invention relates to a calcium carbonate having a surface charge, the preparing process thereof and filler for producing a paper using the same. The present invention provides the process of preparing a calcium carbonate having a surface charge, characterized in that it comprises the following steps of: preparing a solution mixture of one or more monomer selected from the group consisting of calcium hydroxide, acrylic acid, acrylamide, or [2-(acryloyloxy)ethyl]-trimethylammonium chloride; removing dissolved gases such as oxygen and carbon dioxide in the said solution by injecting nitrogen (N2) gas; adjusting pH of the said solution; and inducing a reaction by adding polymerization initiator of a high molecule while injecting carbon dioxide to the said mixture.

Abstract: A method of treating a surface of a substrate using modified urushiol derived from Toxicodendron vernicifluum is provided. More particularly, the reactivity of a hydroxyl group of urushiol extracted from fresh Toxicodendron vernicifluum is removed before the lacquer is used as a UV coating agent for a substrate such as a steel sheet. Therefore, the substrate may have high antibacterial activity, and excellent appearance and functionalities such as far-infrared radiation, blocking of electromagnetic waves, enhanced corrosion resistance, high crosslinking speed when a low content of a photoinitiator is used, excellent surface gloss and high scratch resistance.

Abstract: The present invention relates to a method of preparing water-dispersible poly (urethane-urea) having aliphatic-aromatic isocyanate, more particularly to a method of preparing water-dispersible poly (urethane-urea) having aliphatic-aromatic isocyanate, with improved mechanical/thermal properties, such as heat resistance, chemical resistance and adhesion, good cost competitiveness and environmental friendliness, by reacting polyester polyol, dimethylol propionic acid and an aromatic isocyanate compound to obtain a hydroxyl (OH)-terminated prepolymer, adding an aliphatic isocyanate compound to said OH-terminated prepolymer to obtain an isocyanate (NCO)-terminated prepolymer wherein aromatic-aliphatic isocyanate is hybridized, neutralizing, water-dispersing and chain extending said NCO-terminated prepolymer.

Abstract: Provided is a small form factor optical/magnetic disk including an integrated metal hub and a disk plate. The integrated metal hub includes a circular upper metal hub and a circular lower metal hub integrally formed with and disposed under the upper metal hub. The circular lower metal hub has a smaller diameter smaller than the upper metal hub. A central hole is formed in central portions of the upper and lower metal hubs and passes through the upper and lower metal hubs. The disk plate has a through-hole that is formed in a central portion and is directly associated with the integrated metal hub, and a recess that is formed around the through-hole and allows the upper metal hub to be mounted therein. Since the central portion of the small form factor optical/magnetic disk is not thick, the small form factor optical/magnetic disk can contribute to an ultra thin small form factor information storage device. Also, since manufacturing processes are simple, price and quality competitiveness can be enhanced.

Abstract: Provided are a jig used in a forming a cover layer of a small form factor optical disk and a method forming a cover layer in a small form factor optical disk using the jig. The jig includes: a body; a cylindrical wall formed inside the body and mounting an optical disk plate to a predetermined depth; and a pin positioned in a center of the cylindrical wall and combined with a central hole of the optical disk plate.

Abstract: Provided is a method of manufacturing a form factor disk such as an optical or magnetic disk for use in electronic appliances and information appliances. The method includes forming a hub for readily mounting the disk to a magnetic rotational disk connected to a spindle motor of the information appliances by depositing or plating a magnetic material, whereby it is possible to minimize a thickness of the disk, simplifying a manufacturing process, allowing an ultra-small and ultra-slim form factor disk to be manufactured, and therefore, facilitating ultra-minimization and ultra-slim of the information appliances.

Abstract: Provided is a form factor disk such as an optical or magnetic disk used in electronic appliances and information appliances. The form factor disk includes: a circular plate having a first hole for inserting a rotational shaft, a plurality of second holes formed adjacent to the first hole, and an information storage region formed at a surface thereof; an upper metal hub located on the circular plate, and having a hole aligned with the first hole of the circular plate and column-shaped joints formed at portions corresponding to the second holes of the circular plate; and a lower metal hub located under the circular plate, and having a hole aligned with the first hole of the circular plate and column-shaped joints formed at portions corresponding to the second holes of the circular plate, wherein the joints of the upper and lower metal hubs are jointed through the second holes.

Abstract: Provided is an apparatus and method of initializing a recording layer used in manufacturing a phase-change optical disk for storing information. The optical disk is initialized using a UV lamp in order to initialize the recording layer of the phase-change optical disk capable of repeatedly writing information, without a separate optical head, whereby it is possible to increase productivity by remarkably reducing an initialization time of the optical disk since a large area is initialized using a UV beam.

Abstract: Provided is a method of manufacturing a thin film magnetic head.