Abstract: Systems, methods, and computer program products for estimating a Bayesian hierarchical regression model using parallelized and distributed Gibbs sampling are described. The techniques can be implemented to solve use cases where there is a response variable, e.g., number of store visits or web page visits, which is a variable of interest, and multiple explanatory variables, e.g., locations, temperatures, or prices, that may predict the response variable. The disclosed techniques build a model that explains and quantifies effects of the explanatory variables on the response variable on a distributed system. For instance, the disclosed techniques can build a model which has the capability to estimate that an X-degree increase in temperature at a certain time of year predicts a Y-percent increase in store visits. This estimation process is performed in parallel on multiple nodes of the distributed system.

Abstract: The present disclosure provides a composition containing a sweet potato stem and/or leaf extract for prevention, alleviation, or treatment of an ear disease. The composition according to the present disclosure can suppress hearing loss by effectively inhibiting the increase in hearing threshold due to hearing loss and the damage to hair cells, and is useful for the prevention or treatment of an ear disease, such as hearing loss or ringing in the ears, by having effects of reducing abnormal behavior caused by ringing in the ears and of returning the hearing amplitude to normal, and therefore, the composition can be advantageously used as a pharmaceutical composition or a health functional food.

Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.

Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.